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Anti-SEPT2 Antibody (3M4)

Name: Anti-SEPT2 Antibody (3M4)
Brand: TargetMol
SKU: TMAB-12661
Rating: 4.5 (1 reviews)

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货号 TMAB-12661

Anti-SEPT2 Antibody (3M4) 是一种 Mouse 抗体，靶向 SEPT2。Anti-SEPT2 Antibody (3M4) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-SEPT2 Antibody (3M4)

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货号 TMAB-12661

Anti-SEPT2 Antibody (3M4) 是一种 Mouse 抗体，靶向 SEPT2。Anti-SEPT2 Antibody (3M4) 可用于 WB,IHC-P,IHC-Fr,IF。

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生物活性

产品描述	Anti-SEPT2 Antibody (3M4) is a Mouse antibody targeting SEPT2. Anti-SEPT2 Antibody (3M4) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type	IgG1, Kappa
克隆号	3M4
反应种属	Human (predicted:Mouse,Rat)
应用	WB IHC-P IHC-Fr IF
推荐剂量	WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类	Monoclonal
宿主来源	Mouse
亚细胞定位	Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cleavage furrow. Midbody. Cytoplasm, cell cortex.
组织特异性	Widely expressed. Up-regulated in liver cancer.
构建方式	Recombinant Antibody
纯化方式	Protein G purified
性状	Liquid
缓冲液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度	1mg/ml
研究背景	The septins are a family of cytoskeletal GTPases that play an essential role in cytokinesis in mammalian cells. Septin 2 (Nedd5) is a mammalian septin known to associate with actin based structures such as the contractile ring and stress fibers. It is involved in cytokinesis and may assemble into a multicomponent structure.

抗原信息

基因名称	SEPTIN2
基因ID	4735
蛋白名称	Septin-2
功能	Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

储存&溶解度

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式	Shipping with blue ice.
存储	store at low temperature \| -20°C for 1 year

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