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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ATG3 Antibody (2X547)

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货号 TMAB-02917

Anti-ATG3 Antibody (2X547) 是一种 Rabbit 抗体，靶向 ATG3。Anti-ATG3 Antibody (2X547) 可用于 WB,ICC/IF。

Anti-ATG3 Antibody (2X547)

Anti-ATG3 Antibody (2X547)

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Rating icon 还可以
货号 TMAB-02917

Anti-ATG3 Antibody (2X547) 是一种 Rabbit 抗体，靶向 ATG3。Anti-ATG3 Antibody (2X547) 可用于 WB,ICC/IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-ATG3 Antibody (2X547) is a Rabbit antibody targeting ATG3. Anti-ATG3 Antibody (2X547) can be used in WB,ICC/IF.
Ig Type
IgG
克隆号
2X547
反应种属
Human,Mouse,Rat
应用WBICC/IF
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Widely expressed, with a highest expression in heart, skeletal muscle, kidney, liver and placenta.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景E2 conjugating enzyme that catalyzes the covalent conjugation of the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to the amino group of phosphatidylethanolamine (PE)-containing lipids in the membrane resulting in membrane-bound ATG8-like proteins which is one of the key steps in the development of autophagic isolation membranes during autophagosome formation.
抗原信息
免疫原
A synthesized peptide: human ATG3
抗原种属
Human
基因名称
ATG3
基因ID
64422
蛋白名称
Ubiquitin-like-conjugating enzyme ATG3
Uniprot ID
Q9NT62
功能
E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
化学信息
分子量Theoretical: 36 kDa. Actual: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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