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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-VWF Antibody (9I145)

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货号 TMAB-14151

Anti-VWF Antibody (9I145) 是一种 Rabbit 抗体，靶向 VWF。Anti-VWF Antibody (9I145) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-VWF Antibody (9I145)

Anti-VWF Antibody (9I145)

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Rating icon 还可以
货号 TMAB-14151

Anti-VWF Antibody (9I145) 是一种 Rabbit 抗体，靶向 VWF。Anti-VWF Antibody (9I145) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-VWF Antibody (9I145) is a Rabbit antibody targeting VWF. Anti-VWF Antibody (9I145) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
9I145
反应种属
Human,Mouse
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:800-2000; IHC-Fr: 1:800-2000; IF: 1:800-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules.
组织特异性Plasma.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
浓度1mg/ml
研究背景Von Willebrand Factor (VWF) was previously known as Factor VIII related antigen. VWF is synthesized exclusively by endothelial cells and megakaryocytes, and stored in the intracellular granules or constitutively secreted into plasma. This glycoprotein functions as both an antihemophilic factor carrier and a platelet vessel wall mediator in the blood coagulation system. Important in the maintenance of homeostasis, it participates in platelet vessel wall interactions by forming a noncovalent complex with coagulation factor VIII at the site of vascular injury. The Von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. Mutations in this gene or deficiencies in this protein result in Von Willebrand's disease. VWD is characterized by frequent bleeding (gingival, minor skin quantitative lacerations, menorrhagia, etc.).
抗原信息
免疫原
Recombinant Protein: human VWF protein
抗原种属
Human
基因名称
VWF
基因ID
7450
蛋白名称
von Willebrand factor
Uniprot ID
P04275
功能
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
化学信息
分子量Theoretical: 309 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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