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Anti-PTPN2 Antibody (2V471) 是一种 Mouse 抗体,靶向 PTPN2。Anti-PTPN2 Antibody (2V471) 可用于 WB,IHC-P,IHC-Fr,IF,FCM,FCM。
Anti-PTPN2 Antibody (2V471) 是一种 Mouse 抗体,靶向 PTPN2。Anti-PTPN2 Antibody (2V471) 可用于 WB,IHC-P,IHC-Fr,IF,FCM,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-PTPN2 Antibody (2V471) is a Mouse antibody targeting PTPN2. Anti-PTPN2 Antibody (2V471) can be used in WB,IHC-P,IHC-Fr,IF,FCM,FCM. |
| Ig Type | IgG1, Kappa |
| 克隆号 | 2V471 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrIFFCMFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | [Isoform 2]: Nucleus. Cytoplasm. Cell membrane. Note=Predominantly localizes to chromatin (By similarity). Able to shuttle between the nucleus and the cytoplasm and to dephosphorylate plasma membrane receptors (PubMed:9488479). Recruited by activated ITGA1 at the plasma membrane. {ECO:0000250, ECO:0000269|PubMed:9488479}. |
| 组织特异性 | Ubiquitously expressed. Isoform 2 is probably the major isoform. Isoform 1 is expressed in T-cells and in placenta. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011] |
| 基因名称 | PTPN2 |
| 基因ID | |
| 蛋白名称 | Tyrosine-protein phosphatase non-receptor type 2 |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |