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Anti-SIRT2 Antibody (2O767)

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货号 TMAB-12814

Anti-SIRT2 Antibody (2O767) 是一种 Rabbit 抗体,靶向 SIRT2。Anti-SIRT2 Antibody (2O767) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-SIRT2 Antibody (2O767)

Anti-SIRT2 Antibody (2O767)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12814

Anti-SIRT2 Antibody (2O767) 是一种 Rabbit 抗体,靶向 SIRT2。Anti-SIRT2 Antibody (2O767) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-SIRT2 Antibody (2O767) is a Rabbit antibody targeting SIRT2. Anti-SIRT2 Antibody (2O767) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
2O767
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Colocalizes with microtubules.
组织特异性Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
抗原信息
免疫原
A synthesized peptide: human SIRT2
抗原种属
Human
基因名称
SIRT2
基因ID
蛋白名称
NAD-dependent protein deacetylase sirtuin-2
Uniprot ID
功能
NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton.
化学信息
分子量Theoretical: 36 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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