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PD-L1 Protein, Human, Recombinant (hFc) V2

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产品编号 TMPY-00676U

PD-L1 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q9NZQ7-1.

PD-L1 Protein, Human, Recombinant (hFc) V2

一键复制产品信息

产品编号 TMPY-00676U

PD-L1 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q9NZQ7-1.

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生物活性	Immobilized Human PD-1, mFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human PD-L1, hFc Tag with the EC50 of 0.17 μg/ml determined by ELISA (QC Test). Human PD-L1, hFc Tag captured on CM5 Chip via Protein A can bind Biotinylated Human PD-1, His-Avi Tag with an affinity constant of 2.356 μM as determined in SPR assay (Biacore T200).
产品描述	PD-L1 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q9NZQ7-1.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q9NZQ7-1
蛋白构建	Phe19-Arg238
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	52 kDa (Predicted); 68-80 kDa (Due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.