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Anti-CD14 Antibody (6R885)

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产品编号 TMAH-00168
别名 monocyte differentiation antigen CD14, CD14 molecule, CD14 antigen

Anti-CD14 Antibody (6R885) 是一种抗体,靶向 CD14。Anti-CD14 Antibody (6R885) 可用于 ELISA, IHC。

Anti-CD14 Antibody (6R885)

Anti-CD14 Antibody (6R885)

Rating icon 还可以
产品编号 TMAH-00168 别名 monocyte differentiation antigen CD14, CD14 molecule, CD14 antigen

Anti-CD14 Antibody (6R885) 是一种抗体,靶向 CD14。Anti-CD14 Antibody (6R885) 可用于 ELISA, IHC。

规格价格库存数量
50 μL
¥ 1,310
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100 μL
¥ 2,180
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD14 Antibody (6R885) is an antibody targeting CD14. Anti-CD14 Antibody (6R885) can be used in ELISA, IHC.
别名monocyte differentiation antigen CD14, CD14 molecule, CD14 antigen
Ig Type
hIgG1
克隆号
6R885
交叉反应
Human
验证活性
IHC image of TMAH-00168 diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
应用
ELISA, IHC
推荐剂量
IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CD14 Protein
抗原种属
Human
基因ID
929
Uniprot ID
研究领域
Immunology, Stem cells
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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