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Anti-CD14 Antibody (6R885) 是一种抗体,靶向 CD14。Anti-CD14 Antibody (6R885) 可用于 ELISA, IHC。
Anti-CD14 Antibody (6R885) 是一种抗体,靶向 CD14。Anti-CD14 Antibody (6R885) 可用于 ELISA, IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,310 | 5日内发货 | |
100 μL | ¥ 2,180 | 5日内发货 |
产品描述 | Anti-CD14 Antibody (6R885) is an antibody targeting CD14. Anti-CD14 Antibody (6R885) can be used in ELISA, IHC. |
别名 | monocyte differentiation antigen CD14, CD14 molecule, CD14 antigen |
Ig Type | hIgG1 |
克隆号 | 6R885 |
交叉反应 | Human |
验证活性 | IHC image of TMAH-00168 diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB. |
应用 | ELISA, IHC |
推荐剂量 | IHC:1:50-1:200. |
抗体种类 | Monoclonal |
亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
研究背景 | Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-). |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: Human CD14 Protein |
抗原种属 | Human |
基因ID | 929 |
Uniprot ID | |
研究领域 | Immunology, Stem cells |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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