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别名 p-BTK (Y223), p-BTK (Tyr223), BTK (p-Y223), BTK (p-Tyr223)
Anti-Phospho-BTK (Tyr223) Antibody (1E544) 是一种 Rabbit 抗体,靶向 Phospho-BTK (Tyr223)。Anti-Phospho-BTK (Tyr223) Antibody (1E544) 可用于 WB,IP。
Anti-Phospho-BTK (Tyr223) Antibody (1E544) 是一种 Rabbit 抗体,靶向 Phospho-BTK (Tyr223)。Anti-Phospho-BTK (Tyr223) Antibody (1E544) 可用于 WB,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-Phospho-BTK (Tyr223) Antibody (1E544) is a Rabbit antibody targeting Phospho-BTK (Tyr223). Anti-Phospho-BTK (Tyr223) Antibody (1E544) can be used in IP,WB. |
| 别名 | p-BTK (Y223), p-BTK (Tyr223), BTK (p-Y223), BTK (p-Tyr223) |
| Ig Type | IgG |
| 克隆号 | 1E544 |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of Phospho-BTK (Y223) on different lysates using anti-Phospho-BTK (Y223) antibody at 1/1,000 dilution. Positive control: Lane 1: K562 cells treated with pervanadate, Lane 2: Untreated K562 cell lysate. ![]() |
| 应用 | IPWB |
| 推荐剂量 | WB: 1:1000-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Emt (also known as Itk or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton’s disease. The Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | A synthesized phosphopeptide: human BTK around the phosphorylation site of Tyr223 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 76 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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