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Anti-Phospho-GYS1 (S641) Antibody (6Y642) 是一种 Rabbit 抗体,靶向 Phospho-GYS1 (S641)。Anti-Phospho-GYS1 (S641) Antibody (6Y642) 可用于 WB,ICC,IHC,IP。
Anti-Phospho-GYS1 (S641) Antibody (6Y642) 是一种 Rabbit 抗体,靶向 Phospho-GYS1 (S641)。Anti-Phospho-GYS1 (S641) Antibody (6Y642) 可用于 WB,ICC,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-Phospho-GYS1 (Ser641) Antibody (6Y642) 是一种 Rabbit 抗体,靶向 Phospho-GYS1 (Ser641)。Anti-Phospho-GYS1 (Ser641) Antibody (6Y642) 可用于 WB,ICC,IHC,IP。 |
别名 | Phospho-GYS1 (S641), p-GYS1 (Ser641), p-GYS1 (S641), muscle, GYS1 (p-Ser641), GYS1 (p-S641), Gys 1, GYS, GSY, Glycogen synthase 1, Glycogen [starch] synthase |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of Phospho-Glycogen synthase 1 (S641) on different lysates using anti-Phospho-Glycogen synthase 1 (S641) antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse liver lysate, untreated, Lane 2: Mouse liver lysate, treated with AP. 2. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Phospho-Glycogen synthase 1 (S641) antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-Phospho-Glycogen synthase 1 (S641) antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse smooth muscle tissue using anti-Phospho-Glycogen synthase 1 (S641) antibody. Counter stained with hematoxylin. 5. ICC staining Phospho-Glycogen synthase 1 (S641) in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining Phospho-Glycogen synthase 1 (S641) in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; ICC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Glycogen [starch] synthase belongs to the mammalian/fungal glycogen synthase family of proteins. Two forms of this protein exist, a liver form and a muscle form, both of which have the same function in the glycogen biosynthesis pathway. Glycogen synthase transfers the glycosyl residue from UDP-Glucose to the nonreducing end of ?-1,4-glucan. The liver glycogen synthase protein is truncated by 34 amino acids compared to the muscle form. However, these enzymes differ significantly in their amino- and carboxyl-terminal regions. Muscle glycogen synthase serves to fuel muscular activity only and is regulated by muscle contraction and by catecholamines. Liver glycogen synthase mediates blood glucose homeostasis in response to nutritional cues. Defects in the gene encoding liver glycogen synthase results in glycogen storage disease type 0 (GSD0), a rare form of fasting ketotic hypoglycemia. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human Glycogen synthase 1 around the phosphorylation site of Ser641 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 85 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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