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Anti-ST13 Antibody (3J526)

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货号 TMAB-13176

Anti-ST13 Antibody (3J526) 是一种 Rabbit 抗体,靶向 ST13。Anti-ST13 Antibody (3J526) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-ST13 Antibody (3J526)

Anti-ST13 Antibody (3J526)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13176

Anti-ST13 Antibody (3J526) 是一种 Rabbit 抗体,靶向 ST13。Anti-ST13 Antibody (3J526) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-ST13 Antibody (3J526) is a Rabbit antibody targeting ST13. Anti-ST13 Antibody (3J526) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
克隆号
3J526
反应种属
Human,Mouse
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).
抗原信息
基因名称
ST13
基因ID
蛋白名称
Hsc70-interacting protein
功能
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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