st

Lith-O-Asp is a sialytransferase (ST) inhibitor,(IC50s:12-37 μM).

ST 1535 是有效的，具有口服活性的 A2A 腺苷受体拮抗剂。ST 1535 显示出抗帕金森病活性和抗震颤作用。

ST-1006是一种强效组胺 H4受体激动剂（pKi：7.94）。ST-1006具有抗炎作用。ST-1006是一种有效的嗜碱性粒细胞迁移诱导剂，可诱导嗜碱性粒细胞迁移。 ST-1006 具有抗炎作用和止痒作用。

ST-193是一种 arenavirus 的广谱抑制剂。它抑制 Guanarito, Junin, Lassa 和 Machupo 病毒的 IC50值分别为0.44, 0.62, 1.4 和3.1 nM。

ST-91 是一种 α2-肾上腺素能受体激动剂，具有混合的 α-肾上腺素能受体类型 亚型选择特征。

ST1936 oxalate 是一种 5-HT6 受体的选择性纳摩尔亲和激动剂，对人5-HT6、5-HT7和 5-HT2B 受体的 Ki 值分别为 13、168 和 245 nM。

ST3932 is a ST1535 metabolite, is a adenosine A2A receptor antagonist(Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively).

ST-836 is a dopamine receptor ligand; Antiparkinsonian agent .

ST-836 hydrochloride is a dopamine receptor ligand; Antiparkinsonian agent .

ST4206 is an antagonist of adenosine A2A. For adenosine A2A receptor and adenosine A1 receptor, the Kis values are 12 nM and 197 nM , respectively.

ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 inhibition of IL-1β-mediated activation of NF-κB transcriptional activity.

ST034307 是一种选择性 adenylyl cyclase 1抑制剂，IC50值为 2.3 μM。

FCHFHS-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].

MAC-VC-PABC-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].

ST-IN-1 (compound (R)-1) 作为一种有效的ST抑制剂，展现出显著的抗肿瘤活性（Ki=70 nM, rat a-2,6-ST; Ki=19 nM, hST6GAL1）。该化合物能够通过去脂化肿瘤细胞表面，阻断肿瘤的生长与转移。

ST-539是去泛素化酶USP30的抑制剂，具有0.37 μM的IC50值。它能促进线粒体蛋白的泛素化，诱导线粒体自噬 (autophagy)，从而调节线粒体稳态。ST-539可用于神经退行性疾病的研究。

ST638 是有效的酪氨酸激酶抑制剂（IC50=370 nM）。

ST1936 (ST 1936 oxalate) 是一种具有选择性和高效性的 5-HT6 受体激动剂，抑制人 5-HT6、5-HT7 和 5-HT2B 受体，通过完全激活克隆的人 5-HT6 受体来刺激 cAMP、Ca2+、ERK1 2 和 Fyn 激酶。

ST-1892 is a soluble partial FXR agonist.

ST7710AA1 is a PARP-1 inhibitor that acts by showing significant in vitro target inhibition and capability to substantially bypass the multidrug resistance mediated by Pgp.

ST-148 is a potent inhibitor for Dengue virus capsid. ST-148-enhanced capsid protein self-interaction perturbs assembly and disassembly of DV nucleocapsids, probably by inducing structural rigidity.

ST-168 is a potent inhibitor of PI3K and MEK. ST-168 displays improved PI3K and MEK1 isoform inhibition. ST-168 demonstrated a 2.8-, 2.7-, 23-, and 2.5-fold improved inhibition toward the PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ isoforms and a 2.2-fold improvement

ST-198 is a dopamine D3 receptor antagonist.

ST362, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.