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别名 Tecvayli, teclistamab-cqyv
Anti-Teclistamab Antibody (2P677) 是一种 Mouse 抗体,靶向 Teclistamab。Anti-Teclistamab Antibody (2P677) 可用于 ELISA, Sandwich ELISA, Competitive ELISA。
Anti-Teclistamab Antibody (2P677) 是一种 Mouse 抗体,靶向 Teclistamab。Anti-Teclistamab Antibody (2P677) 可用于 ELISA, Sandwich ELISA, Competitive ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 40 μg | ¥ 1,609 | 5日内发货 |
| 产品描述 | Anti-Teclistamab Antibody (2P677) is a Mouse antibody targeting Teclistamab. Anti-Teclistamab Antibody (2P677) can be used in ELISA, Sandwich ELISA, Competitive ELISA. |
| 别名 | Tecvayli, teclistamab-cqyv |
| Ig Type | IgG1, κ |
| 克隆号 | 2P677 |
| 特异性 | Teclistamab |
| 应用 | ELISASandwich ELISACompetitive ELISA |
| 推荐剂量 | ELISA: 0.01-1 µg/ml; Sandwich ELISA: 0.5-2 μg/ml; Competitive ELISA: 1-10 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 纯化方式 | Protein A affinity column |
| 性状 | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| 缓冲液 | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| 研究背景 | Teclistamab, also known as Tecvayli, is a therapeutic monoclonal antibody specifically designed to address relapsed and refractory multiple myeloma. It is a bispecific antibody that effectively targets both the CD3 receptor found on T-cells and the B-cell maturation antigen (BCMA) expressed on malignant multiple myeloma B-lineage cells. Teclistamab is composed of two arms, one targeting BCMA and the other targeting CD3. These arms are connected by two interchain disulfide bonds, enabling the drug to engage CD3-expressing T cells and direct them towards BCMA-expressing cells. This mechanism facilitates T cell-mediated cytotoxicity to combat the targeted cells. |
| 偶联 | Unconjugated |
| 免疫原 | Teclistamab |
| 储存方式 | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | -20°C for 1 year |