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Astaxanthin

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纯度: 99.79%

货号 T3138Cas号 472-61-7

别名 虾青素, β-Carotene-4,4'-dione, trans-Astaxanthin, Ovoester, AstaREAL

Astaxanthin (trans-Astaxanthin) 是可从雨生红球藻等多种海洋生物中提取得到的红色类胡萝卜素,是过氧化物酶体增殖物活化受体γ 的调节剂,具有抗增殖、神经保护作用和抗炎活性。它是一种抗氧化剂,有用于癌症和心血管疾病的研究潜力,作为颜色添加剂用于动物食品中。

Astaxanthin

Astaxanthin

一键复制产品信息
Rating icon 很棒

纯度: 99.79%

货号 T3138 别名 虾青素, β-Carotene-4,4'-dione, trans-Astaxanthin, Ovoester, AstaREALCas号 472-61-7

Astaxanthin (trans-Astaxanthin) 是可从雨生红球藻等多种海洋生物中提取得到的红色类胡萝卜素,是过氧化物酶体增殖物活化受体γ 的调节剂,具有抗增殖、神经保护作用和抗炎活性。它是一种抗氧化剂,有用于癌症和心血管疾病的研究潜力,作为颜色添加剂用于动物食品中。

规格价格库存数量
2 mg
¥ 235
现货
5 mg
¥ 413
现货
10 mg
¥ 578
现货
25 mg
¥ 963
现货
50 mg
¥ 1,420
现货
100 mg
¥ 2,120
现货
500 mg
¥ 4,970
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产品介绍


生物活性
产品描述
Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aquatic organisms. Astaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions. It may be found in fish feed or some animal food as a color additive.
别名虾青素, β-Carotene-4,4'-dione, trans-Astaxanthin, Ovoester, AstaREAL
化学信息
分子量596.84
分子式C40H52O4
CAS No.472-61-7
SmilesC\C(\C=C\C=C(/C)\C=C\C1=C(C)C(=O)[C@@H](O)CC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C(=O)[C@@H](O)CC1(C)C
密度1.071 g/cm3
储存&溶解度
存储store at low temperature,keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
DMSO: 5.97 mg/mL (10 mM), Sonication is recommended.
DMF: 1 mg/mL (1.68 mM), Sonication is recommended.
溶液配制表
DMF/DMSO
1mg5mg10mg50mg
1 mM1.6755 mL8.3775 mL16.7549 mL83.7745 mL
DMSO
1mg5mg10mg50mg
5 mM0.3351 mL1.6755 mL3.3510 mL16.7549 mL
10 mM0.1675 mL0.8377 mL1.6755 mL8.3775 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
TargetMol | Animal experiments 比如您的给药剂量是10 mg/kg,每只动物体重20g,给药体积100 μLTargetMol | Animal experiments 一共给药动物10只,您使用的配方为5%TargetMol | reagent DMSO + 30%PEG300 + 5%Tween 80 + 60%Saline/PBS/ddH2O, 那么您的工作液浓度为2mg/mL
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent ( 母液浓度为 40 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:50μLDMSOTargetMol | reagent 母液,添加 300 μLPEG300TargetMol | reagent 混匀澄清,再加 50μLTween80, 混匀澄清,再加 600μLSaline/PBS/ddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如: DMSOPEG300 / PEG400Tween 80SBE-β-CD玉米油 等, 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

TargetMol AI Summary
Astaxanthin exhibits diverse pharmacological activities including antiradical, antiplasmodial, hypoglycemic, antidiabetic, antiviral, and inhibitory effects on specific proteins. It acts as a DPPH radical scavenger with a 52.0% activity at a concentration of 1500 µM. It shows antiplasmodial activity against Plasmodium falciparum strains W2, 7G8, and GB4 with IC50 values of 7943.28 nM for the W2 and 7G8 strains, and 12589.25 nM for the GB4 strain. In mouse models, at a dosage of 10 mg/kg, it reduces plasma glucose levels, demonstrating hypoglycemic activity by lowering glucose levels by 6.02 mmol/L and 6.14 mmol/L in oral glucose tolerance tests, and antidiabetic activity by reducing glucose levels by 10.11 mmol/L and 13.03 mmol/L in an alloxan-induced diabetic model. Astaxanthin inhibits the activity of OATP1B1 and OATP1B3 in CHO cells with inhibition rates of 95.25% and 87.19% respectively at 10 µM. It also shows antiviral activity by reducing SARS-CoV-2 induced cytotoxicity in Caco-2 cells by approximately 29.9% at a concentration of 10 µM after 48 hours and slightly inhibits SARS-CoV-2 3CL-Pro protease by 17.74% at a concentration of 20 µM. Furthermore, it inhibits the cytotoxicity of SARS-CoV-2 in VERO-6 cells by 2.6% at 10 µM concentration after 48 hours and shows a 10.39% inhibitory activity against human HDAC6 with a commercial peptide substrate, although it does not inhibit with a custom peptide substrate..
Note: Summary generated by AI, AI may be wrong some times, we do not provide any medical advice and only sell our product to accredited institution, Please cross-check with other sources, data source: chembl
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