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顶部产品介绍化学信息储存和溶解信息计算器

N-butyryl-L-Homocysteine thiolactone

货号 T37342Cas号 202284-85-3 一键复制产品信息
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Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, the small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism. N-butyryl-L-Homocysteine thio-lactone induces violacein expression in C. violaceum mutants usually not able to produce AHLs.

N-butyryl-L-Homocysteine thiolactone

一键复制产品信息
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货号 T37342Cas号 202284-85-3

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, the small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism. N-butyryl-L-Homocysteine thio-lactone induces violacein expression in C. violaceum mutants usually not able to produce AHLs.

N-butyryl-L-Homocysteine thiolactone
规格价格库存数量
5 mg
¥ 1,080
35日内发货
10 mg
¥ 2,130
35日内发货
25 mg
¥ 4,880
35日内发货
50 mg
¥ 8,130
35日内发货
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产品介绍

生物活性
产品描述
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, the small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism. N-butyryl-L-Homocysteine thio-lactone induces violacein expression in C. violaceum mutants usually not able to produce AHLs.
化学信息
分子量187.26
分子式C8H13NO2S
CAS No.202284-85-3
SmilesCCCC(=O)N[C@H]1CCSC1=O
储存&溶解度
存储
溶解度信息
DMF: 50 mg/mL (267.01 mM), Sonication is recommended.
Ethanol: 25 mg/mL (133.5 mM), Sonication is recommended.
DMSO: 30 mg/mL (160.21 mM), Sonication is recommended.
PBS (pH 7.2): 0.5 mg/mL (2.67 mM), Sonication is recommended.
溶液配制表
PBS (pH 7.2)/Ethanol/DMSO/DMF
1mg5mg10mg50mg
1 mM5.3402 mL26.7008 mL53.4017 mL267.0084 mL
Ethanol/DMSO/DMF
1mg5mg10mg50mg
5 mM1.0680 mL5.3402 mL10.6803 mL53.4017 mL
10 mM0.5340 mL2.6701 mL5.3402 mL26.7008 mL
20 mM0.2670 mL1.3350 mL2.6701 mL13.3504 mL
50 mM0.1068 mL0.5340 mL1.0680 mL5.3402 mL
100 mM0.0534 mL0.2670 mL0.5340 mL2.6701 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

N-butyryl-L-Homocysteine thiolactoneNbutyrylLHomocysteine thiolactoneN butyryl L Homocysteine thiolactone
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