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Anti-Phospho-STAT5b (Ser731) Polyclonal Antibody 2

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货号 TMAB-11326

Anti-Phospho-STAT5b (Ser731) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-STAT5b (Ser731)。Anti-Phospho-STAT5b (Ser731) Polyclonal Antibody 2 可用于 FCM。

Anti-Phospho-STAT5b (Ser731) Polyclonal Antibody 2

Anti-Phospho-STAT5b (Ser731) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-11326

Anti-Phospho-STAT5b (Ser731) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-STAT5b (Ser731)。Anti-Phospho-STAT5b (Ser731) Polyclonal Antibody 2 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-STAT5b (Ser731) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-STAT5b (Ser731). Anti-Phospho-STAT5b (Ser731) Polyclonal Antibody 2 can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human STAT5b around the phosphorylation site of Ser731
抗原种属
Human
基因名称
STAT5B
基因ID
6777
蛋白名称
Signal transducer and activator of transcription 5B
Uniprot ID
P51692
功能
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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