Name: (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin
Brand: TargetMol
SKU: T17339
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

100 mg

待询

500 mg

待询

生物活性

产品描述	(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin is a polyethylene glycol (PEG)-based PROTAC linker utilized for the synthesis of PROTACs.
体外活性	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

化学信息

分子量	2288.64
分子式	C₁₁₄H₁₆₂N₂₂O₂₈
Smiles	CN(C1=CC2=C(C(C3=CC=C(C(NCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCC(NCCOCCOCCOCCNC(CCCCC[C@@H]4[C@H](C)NC(N4)=O)=O)=O)=O)=O)C=C3C([O-])=O)=C5C=C/C(C=C5O2)=[N+](C)/C)C=C1)C.CN(C6=CC7=C(C(C8=CC(C(NCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCC(NCCOCCOCCOCCNC(CCCCC[C@@H]9[C@H](C)NC(N9)=O)=O)=O)=O)=O)=CC=C8C([O-])=O)=C%10C=C/C(C=C%10O7)=[N+](C)/C)C=C6)C
密度	1.31g/cm3