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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Progestin Receptor Beta Polyclonal Antibody

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货号 TMAB-11774

Anti-Progestin Receptor Beta Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Progestin Receptor Beta。Anti-Progestin Receptor Beta Polyclonal Antibody 可用于 WB。

Anti-Progestin Receptor Beta Polyclonal Antibody

Anti-Progestin Receptor Beta Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11774

Anti-Progestin Receptor Beta Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Progestin Receptor Beta。Anti-Progestin Receptor Beta Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Progestin Receptor Beta Polyclonal Antibody is a Rabbit antibody targeting Progestin Receptor Beta. Anti-Progestin Receptor Beta Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane. Multi-pass membrane protein. Note: Colocalizes with a lysosomal protein cathepsin D.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Five distinct groups, designated Alpha, Beta, Gamma, Delta, comprise the mPR gene family. mPR Alpha, also designated progestin and adipo Theta receptor family member VII (PAQR7), consists of an extracellular N-terminus, an intracellular C-terminus and seven transmembrane domains. mPR Alpha is expressed in ovary, testis, placenta, uterus and bladder. mPR Beta, or progestin and adipo Theta receptor family member VIII (PAQR8), consists of eight putative transmembrane regions and an intracellular N-terminus that contains a leucine-rich motif. mPR Beta is a 354 amino acid protein expressed in brain and spinal cord. Both mPR Alpha and mPR Beta may be G protein-coupled receptors and may be involved in oocyte maturation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Progestin Receptor Beta
抗原种属
Human
基因名称
PAQR8
基因ID
85315
蛋白名称
Membrane progestin receptor betaPAQR8
Uniprot ID
Q8TEZ7
功能
MPRb (Membrane progestin receptor beta) is a steroid membrane receptor and binds progesterone. MPRb may be involved in oocyte maturation. MPRb is an integral membrane protein and is expressed in brain and testis. It belongs to the ADIPOR family.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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