Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Camonagrel 是一种化合物,对Prostaglandin E2具有抑制作用。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 2,960 | 现货 | ||
5 mg | ¥ 6,860 | 现货 | ||
10 mg | ¥ 9,430 | 现货 | ||
25 mg | ¥ 13,800 | 现货 | ||
50 mg | ¥ 18,900 | 现货 | ||
100 mg | ¥ 25,500 | 现货 |
产品描述 | Camonagrel is a compound that has inhibitory effects on Prostaglandin E2. |
体内活性 |
In cats camonagrel (10 mg/kg i.v.) produced not only a fall in TXB2 but also a rise in 6-keto-PGF1 alpha and no change in cyclic-GMP plasma levels.[1] camonagrel (800 mg orally) suppressed TXA2 generation by 99.5% and doubled the plasma level of 6-keto-PGF1 alpha.[1] The greatest reduction in percentage subendothelial surface occupied by platelets (mainly in the thrombi) after blood perfusion was seen after incubation with camonagrel in the range of concentrations that inhibited collagen-induced platelet aggregation. In conclusion, camonagrel reduced platelet-subendothelium interaction under flow conditions, showing this effect in a range of concentrations lower than in inhibition of platelet aggregation.[2] |
分子量 | 272.3 |
分子式 | C15H16N2O3 |
CAS No. | 105920-77-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (73.45 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.6724 mL | 18.3621 mL | 36.7242 mL | 91.8105 mL |
5 mM | 0.7345 mL | 3.6724 mL | 7.3448 mL | 18.3621 mL | |
10 mM | 0.3672 mL | 1.8362 mL | 3.6724 mL | 9.1811 mL | |
20 mM | 0.1836 mL | 0.9181 mL | 1.8362 mL | 4.5905 mL | |
50 mM | 0.0734 mL | 0.3672 mL | 0.7345 mL | 1.8362 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Camonagrel 105920-77-2 Inhibitor inhibitor inhibit