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Anti-Streptolysin O Polyclonal Antibody

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货号 TMAB-13246

Anti-Streptolysin O Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Streptolysin O。Anti-Streptolysin O Polyclonal Antibody 可用于 WB。

Anti-Streptolysin O Polyclonal Antibody

Anti-Streptolysin O Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13246

Anti-Streptolysin O Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Streptolysin O。Anti-Streptolysin O Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Streptolysin O Polyclonal Antibody is a Rabbit antibody targeting Streptolysin O. Anti-Streptolysin O Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Streptococcus
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted; Host cell membrane.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Streptolysin is a streptococcal hemolytic exotoxin. Types include streptolysin O (SLO), which is oxygen-labile, and streptolysin S (SLS), which is oxygen-stable. An antibody, antistreptolysin O, can be detected in an antistreptolysin O titre. Streptolysin O is hemolytically active only in a reversibly reduced state, unlike streptolysin S, which is stable in the presence of oxygen. Another difference is that SLO is antigenic, while SLS is not antigenic due to its small size. The main function of streptolysin O is to cause hemolysis (the breaking open of red blood cells) — in particular, beta-hemolysis. Increased levels of aso titre in the blood could cause damage to the heart and joints. In most cases, penicillin is used to treat patients with increased levels of aso titre.
抗原信息
免疫原
Recombinant Protein: Streptolysin O
功能
Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).
化学信息
分子量Theoretical: 64 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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