购物车
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Sclerostin Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12579

Anti-Sclerostin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Sclerostin。Anti-Sclerostin Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Sclerostin Polyclonal Antibody

Anti-Sclerostin Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12579

Anti-Sclerostin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Sclerostin。Anti-Sclerostin Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-Sclerostin Polyclonal Antibody is a Rabbit antibody targeting Sclerostin. Anti-Sclerostin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteeoblasts differentiated for 21 days.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Negative regulator of bone growth.Sclerostin (SOST) is a bone morphogenetic protein (BMP) antagonist, leading to the activation of BMP signaling. It negatively regulates the formation of bone by repressing the differentiation and/or function of osteoblasts induced by BMPs. It has been shown that Sclerostin binds BMP-5, -6, and -7 with high affinity and BMP-2 and -4 with low affinity. The noggin-sclerostin protein complex represents a novel mechanism for the fine-tuning of BMP activity in bone homeostasis. Evidence is accumulating that one of the important mechanisms of bone regulation by sclerostin is the modulation of Wnt/Beta-catenin signaling. Sclerostin also rapidly activated ERK-1/2 MAPK signaling, indicating the involvement of additional signaling pathways
抗原信息
免疫原
KLH conjugated synthetic peptide: human Sclerostin
抗原种属
Human
基因名称
SOST
基因ID
50964
蛋白名称
Sclerostin
Uniprot ID
Q9BQB4
功能
Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
化学信息
分子量Theoretical: 21 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
Related Tags: buy Anti-Sclerostin Polyclonal Antibody | purchase Anti-Sclerostin Polyclonal Antibody | Anti-Sclerostin Polyclonal Antibody cost | order Anti-Sclerostin Polyclonal Antibody | Anti-Sclerostin Polyclonal Antibody molecular weight