2,6-Dimethylbenzoquinone

Name: 2,6-Dimethylbenzoquinone
Brand: TargetMol
SKU: T4406
Price: 99 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.98%

货号 T4406Cas号 527-61-7

别名 m-Xyloquinone, 2,6-二甲基苯醌, 2,6-Dimethylquinone

2,6-Dimethylbenzoquinone (2,6-Dimethylquinone) 是一种苯醌，一种存在于呕吐萝芙木和 Tibouchina pulchra 中的化合物。在生理浓度下 2, 6-Dimethoxy-p-benzoquinone 是一种抗菌物质。

2,6-Dimethylbenzoquinone

一键复制产品信息

很棒

纯度: 99.98%

货号 T4406 别名 m-Xyloquinone, 2,6-二甲基苯醌, 2,6-DimethylquinoneCas号 527-61-7

规格	价格	库存	数量
100 mg	¥ 99	现货
1 mL x 10 mM (in DMSO)	¥ 99	现货

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产品介绍

2,6-Dimethylbenzoquinone AI Summary

2,6-Dimethylbenzoquinone exhibits a range of biological activities and physicochemical properties. It shows in vitro cytotoxicity against Human Chronic Leukemia K562 cells with an IC50 of 1250.0 nM but demonstrates no interstrand DNA cross-linking efficiency at both 10 µM and 100 µM concentrations. The compound's HPLC capacity factor (logK) is 0.136, with a partition coefficient (logP) of 1.22, indicating its retention time in HPLC and its ability to partition between two immiscible phases, respectively. In various enzyme assays, 2,6-Dimethylbenzoquinone affects the maximum rate of reaction (Vmax) in Escherichia coli WrbA and Bacillus subtilis Succinate-ubiquinone oxidoreductase, and demonstrates substrate affinity (Km) and Vmax alteration in Rhodobacter capsulatus NADH-ubiquinone oxidoreductase. The compound also reacts with glutathione, retaining 22.0% activity at 1 mM concentration in the presence of PBS and EDTA buffer at pH 7.4. It exhibits anticancer activities with IC50 values ranging from 2900.0 nM to 5200.0 nM against cell lines A2780, OVCAR8, and A2780cis after 72 hours, and an antiplasmodial activity with an IC50 of 10400.0 nM against Plasmodium falciparum Dd2. The selectivity index between SV-40 immortalized human ovarian epithelial cells and A2780cis cells is 1.7. 2,6-Dimethylbenzoquinone has an aqueous solubility of 5043.0 μg/mL in phosphate buffer at pH 7.4 after 24 hours..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	2,6-Dimethylbenzoquinone (2,6-Dimethylquinone) is a benzoquinone, a chemical compound found in Rauvolfia vomitoria and in Tibouchina pulchra.At physiological concentrations 2, 6-Dimethoxy-p-benzoquinone is an antibacterial substance
别名	m-Xyloquinone, 2,6-二甲基苯醌, 2,6-Dimethylquinone

化学信息

分子量	136.15
分子式	C₈H₈O₂
CAS No.	527-61-7
Smiles	CC1=CC(=O)C=C(C)C1=O
密度	1.115g/cm3
颜色	White
物理性状	Viscous

储存&溶解度

存储

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 50 mg/mL (367.24 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.3448 mL	36.7242 mL	73.4484 mL	367.2420 mL
5 mM	1.4690 mL	7.3448 mL	14.6897 mL	73.4484 mL
10 mM	0.7345 mL	3.6724 mL	7.3448 mL	36.7242 mL
20 mM	0.3672 mL	1.8362 mL	3.6724 mL	18.3621 mL
50 mM	0.1469 mL	0.7345 mL	1.4690 mL	7.3448 mL
100 mM	0.0734 mL	0.3672 mL	0.7345 mL	3.6724 mL