Name: Tesidolumab
Brand: TargetMol
SKU: T76831
Price: 1650 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 1,650

现货

2 mg

¥ 2,670

现货

5 mg

¥ 4,790

现货

10 mg

¥ 6,680

现货

25 mg

¥ 9,920

现货

50 mg

¥ 13,300

现货

100 mg

¥ 17,800

现货

生物活性

产品描述	Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cutting of C5 and preventing the subsequent formation of membrane attack complex, which can be used to study extravascular hemolysis.
体外活性	Tesidolumab（LFG316）在人体内的半衰期约为9天。与eculizumab和ravulizumab不同，Tesidolumab（LFG316）绑定到一个远离Arg 885的独特表位上[1]。
别名	特度鲁单抗, LFG316
反应种属	Human
验证活性	Immobilized Human Complement C5 Protein (His & Flag) (TMPY-05057) at 1 μg/mL (100 μL/well) can bind Tesidolumab. The EC50 is 1.61 ng/mL.
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型	Human IgG1 lambda2
推荐同型对照	Human IgG1 lambda2, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

基因ID	727
Uniprot ID	P01031
靶点	Complement C5

化学信息

分子量	144.16 kDa
CAS No.	1531594-08-7

储存&溶解度

存储	-20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Tesidolumab

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