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Anti-ICOS ligand Antibody (6Y133)
还可以产品编号 TMAY-01902
别名 LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2
Anti-ICOS ligand Antibody (6Y133) 是一种 Mouse 抗体，靶向 ICOS ligand。Anti-ICOS ligand Antibody (6Y133) 可用于 ELISA(Cap)。
Anti-ICOS ligand Antibody (6Y133)
Anti-ICOS ligand Antibody (6Y133)
还可以产品编号 TMAY-01902 别名 LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2
Anti-ICOS ligand Antibody (6Y133) 是一种 Mouse 抗体，靶向 ICOS ligand。Anti-ICOS ligand Antibody (6Y133) 可用于 ELISA(Cap)。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 585 | 5日内发货 | |
| 100 μL | ¥ 1,689 | 5日内发货 |
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产品介绍
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抗原信息
| 产品描述 | Anti-ICOS ligand Antibody (6Y133) is a Mouse antibody targeting ICOS ligand. Anti-ICOS ligand Antibody (6Y133) can be used in ELISA(Cap). |
| 别名 | LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6Y133 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ICOSL / ICOS ligand / B7-h2 (rh ICOSL / ICOS ligand / B7-h2; TMPY-01672; NP_056074.1; Met1-Ser258). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. The present study shows that ICOSL displays a marked oligomerization potential, resembling more like B7-1 than B7-2. B7-H2-dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. The CD28/B7 and ICOS/B7-H2 pathways are both critical for costimulating T cell immune responses. Deficiency in either pathway results in defective T cell activation, cytokine production, and germinal center formation.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human ICOSL / ICOS ligand / B7-h2 Protein (TMPY-01672) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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