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顶部生物活性储存和溶解信息计算器

Anti-ICOS ligand Antibody (6Y133)

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产品编号 TMAY-01902

别名 LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2

Anti-ICOS ligand Antibody (6Y133) 是一种 Mouse 抗体，靶向 ICOS ligand。Anti-ICOS ligand Antibody (6Y133) 可用于 ELISA(Cap)。

Anti-ICOS ligand Antibody (6Y133)

Anti-ICOS ligand Antibody (6Y133)

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产品编号 TMAY-01902 别名 LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2

Anti-ICOS ligand Antibody (6Y133) 是一种 Mouse 抗体，靶向 ICOS ligand。Anti-ICOS ligand Antibody (6Y133) 可用于 ELISA(Cap)。

规格价格库存数量
20 μL
¥ 585
5日内发货
100 μL
¥ 1,689
5日内发货
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产品介绍

生物活性
产品描述
Anti-ICOS ligand Antibody (6Y133) is a Mouse antibody targeting ICOS ligand. Anti-ICOS ligand Antibody (6Y133) can be used in ELISA(Cap).
别名LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2
Ig Type
Mouse IgG1
克隆号
6Y133
交叉反应
Human
特异性
Human B7-H2/ICOSLG
应用ELISA(Cap)
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ICOSL / ICOS ligand / B7-h2 (rh ICOSL / ICOS ligand / B7-h2; TMPY-01672; NP_056074.1; Met1-Ser258). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. The present study shows that ICOSL displays a marked oligomerization potential, resembling more like B7-1 than B7-2. B7-H2-dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. The CD28/B7 and ICOS/B7-H2 pathways are both critical for costimulating T cell immune responses. Deficiency in either pathway results in defective T cell activation, cytokine production, and germinal center formation.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human ICOSL / ICOS ligand / B7-h2 Protein (TMPY-01672)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

GL-50GL 50CD-275CD 275

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4个月前
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