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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ABCG2 Polyclonal Antibody 2

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货号 TMAB-02163

Anti-ABCG2 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ABCG2。Anti-ABCG2 Polyclonal Antibody 2 可用于 ICC/IF,FCM。

Anti-ABCG2 Polyclonal Antibody 2

Anti-ABCG2 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-02163

Anti-ABCG2 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ABCG2。Anti-ABCG2 Polyclonal Antibody 2 可用于 ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-ABCG2 Polyclonal Antibody 2 is a Rabbit antibody targeting ABCG2. Anti-ABCG2 Polyclonal Antibody 2 can be used in ICC/IF,FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用ICC/IFFCM
推荐剂量
ICC/IF: 1:100-500; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Highly expressed in placenta. Low expression in small intestine, liver and colon.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123. Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ABCG2
抗原种属
Human
基因名称
ABCG2
基因ID
9429
蛋白名称
Broad substrate specificity ATP-binding cassette transporter ABCG2
Uniprot ID
Q9UNQ0
功能
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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