规格

价格

库存

数量

10 mg

待询

10-14周

50 mg

待询

10-14周

生物活性

产品描述

Dimephosphon is an anti-inflammatory agent exhibiting both antihistamine and antiserotonin activities. It aids in maintaining spinal cord conduction function and reduces the excitability of motor neurons around lesion areas. Additionally, Dimephosphon directly stimulates lymph vessel movement, enhancing lymph circulation. This compound is useful for studying inflammatory edema, acute spinal cord injuries, and lymphatic circulation disorders.

体内活性

Dimephosphin 的抗组胺和抗血清素活性已在通过足底注射炎症介质和调节剂诱导的爪水肿模型中得到验证。Dimephosphin (2.5% Dimephosphin 溶液，1 mL，每日一次，连续 10 天) 促进了脊髓损伤杂种犬的脊髓传导功能恢复，其机制可能涉及抗水肿、血管保护以及降低神经元过度兴奋。 Dimephosphin (50 mg/kg，腹腔注射，一次给药) 通过直接激活大鼠淋巴管收缩 (刺激管壁和瓣膜肌细胞) 增强淋巴循环。