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Anti-Caspase-14 Antibody (2C577)
还可以产品编号 TMAY-02111
别名 caspase 14, apoptosis-related cysteine peptidase, ARCI12
Anti-Caspase-14 Antibody (2C577) 是一种 Mouse 抗体，靶向 Caspase-14。Anti-Caspase-14 Antibody (2C577) 可用于 IHC-P。
Anti-Caspase-14 Antibody (2C577)
Anti-Caspase-14 Antibody (2C577)
还可以产品编号 TMAY-02111 别名 caspase 14, apoptosis-related cysteine peptidase, ARCI12
Anti-Caspase-14 Antibody (2C577) 是一种 Mouse 抗体，靶向 Caspase-14。Anti-Caspase-14 Antibody (2C577) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,689 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Caspase-14 Antibody (2C577) is a Mouse antibody targeting Caspase-14. Anti-Caspase-14 Antibody (2C577) can be used in IHC-P. |
| 别名 | caspase 14, apoptosis-related cysteine peptidase, ARCI12 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2C577 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human CASP14 in human stomach with mouse monoclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human CASP14 in human skin with mouse monoclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:500-1:3000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Caspase-14/CASP14 (rh Caspase-14/CASP14; TMPY-01824; NP_036246.1; Ser2-Gln242). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Caspase-14/CASP14 Protein (TMPY-01824) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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