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顶部生物活性储存和溶解信息计算器

Anti-HLA-E Antibody (6I53)

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Anti-HLA-E Antibody (6I53)
产品编号 TMAC-01974
别名 MHC class I antigen E, HLA-E, HLAE, HLA-6.2, HLA class I histocompatibility antigen, alpha chain E, alpha chain E

Anti-HLA-E Antibody (6I53) 是一种 Mouse 抗体，靶向 HLA-E。Anti-HLA-E Antibody (6I53) 可用于 WB,IP,FCM。

Anti-HLA-E Antibody (6I53)

Anti-HLA-E Antibody (6I53)

Rating icon 还可以
Anti-HLA-E Antibody (6I53)
产品编号 TMAC-01974 别名 MHC class I antigen E, HLA-E, HLAE, HLA-6.2, HLA class I histocompatibility antigen, alpha chain E, alpha chain E

Anti-HLA-E Antibody (6I53) 是一种 Mouse 抗体，靶向 HLA-E。Anti-HLA-E Antibody (6I53) 可用于 WB,IP,FCM。

规格价格库存数量
50 μL
¥ 1,990
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-HLA-E Antibody (6I53) is a Mouse antibody targeting HLA-E. Anti-HLA-E Antibody (6I53) can be used in WB,IP,FCM.
别名MHC class I antigen E, HLA-E, HLAE, HLA-6.2, HLA class I histocompatibility antigen, alpha chain E, alpha chain E
交叉反应
Human
验证活性
1. Western blot analysis of HLA-E expression in human PBL (A), BJAB (B), CCRF- CEM (C) and AML-193 (D) whole cell lysates.
应用
WB
IP
FCM
推荐剂量
WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) FCMM: 1 μg per 1 x 106 cells; FCM: 1 μg per 1 x 106 cells
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Major histocompatibility complex (MHC) molecules, which include human leukocyte antigens (HLAs), form an integral part of the immune response system. They are cell surface receptors that bind foreign peptides and present them to cytotoxic T lymphocytes (CTLs). MHC class I molecules consist of two polypeptide chains, an α or heavy chain and a non-covalently associated pro- tein, β-2-Microglobulin. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. HLA-A is a MHC class I heavy chain molecule that plays a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. HLA-B and HLA-C are proteins encod- ed by closely related genes that also exist in the MHC class I. HLA-E belongs to the HLA class I heavy chain paralog. HLA-E is a heterodimer consisting of a heavy chain and a light chain; the heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant HLA-E of human origin
抗原种属
human
Uniprot ID
P13747
化学信息
分子量Theoretical: 40 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

α-chain Eαchain Eα chain EHLA6.2HLA class I histocompatibility antigen, α chain EHLA class I histocompatibility antigen, a chain Ealpha-chain Ea-chain Ea chain E

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