Name: Strictosidinic acid
Brand: TargetMol
SKU: TN2240
Price: 4980 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 4,980

现货

生物活性

产品描述	Strictosidinic acid is a glycosylated indole monoterpene alkaloid isolated from the leaves of Psychotria myriantha. Strictosidinic acid exhibits oral bioactivity, inhibiting the precursor enzymes involved in 5-HT biosynthesis and reducing 5-HT levels. Strictosidinic acid possesses analgesic and antipyretic activity.
体外活性	方法：大鼠脑线粒体与不同浓度 Strictosidinic acid(0.1–500 μg/mL)，在37°C预孵育30分钟，荧光法检测MAO-A和MAO-B的活性抑制率。结果：Strictosidinic acid浓度依赖性地抑制MAO-A活性，IC50 = 150.1 ± 1.25 μg/mL，最大抑制率为 68.67% 。[1]
体内活性	方法：雄性Wistar大鼠腹腔注射 Strictosidinic acid (10 mg/kg)，给药后60分钟处死，取海马组织。结果：与对照组相比，Strictosidinic acid 处理组海马内 5-HT水平降低63.4%，DOPAC水平降低67.4% 。[1]
别名	异胡豆苷酸

化学信息

分子量	516.54
分子式	C₂₆H₃₂N₂O₉
CAS No.	150148-81-5
Smiles	C([C@H]1C2=C(C=3C(N2)=CC=CC3)CCN1)[C@H]4[C@@H](C=C)[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)OC=C4C(O)=O
密度	1.50 g/cm3 (Predicted)

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Strictosidinic acid