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抗抑郁症化合物库

抗抑郁症化合物库

产品编号 L9860 Antidepressant Compound Library
  库化合物信息   Excel SDF

抑郁症是一种常见的精神障碍,世界卫生组织(WHO)发布的统计报告显示,世界上有超过3.5亿人受抑郁症困扰,并且还在快速增长中。抑郁症主要表现为注意力不集中、情绪低落、思维迟缓、睡眠紊乱,食欲体重变化等症状,还会产生悲观厌世甚至自杀想法,每年有超过80万人因抑郁症自杀身亡。 药物治疗作为抑郁症治疗的主要手段,近几十年来开发了一系列抗抑郁药物,但现有抗抑郁药物有一定的局限性,如临床效应滞后或低反应,以及一系列潜在的副作用,抗抑郁药物的发展和抑郁症的发病相比相对比较缓慢,开发抗抑郁症药物已被WHO 列入21世纪迫切开发的药物 TargetMol 抗抑郁症化合物库收集了1181 种与抑郁症相关的化合物,包括已经报道具有抑郁症治疗作用的化合物,以及靶向抑郁症相关靶点的化合物,是抗抑郁症药物研发的良好工具。

TargetMol的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。
TargetMol Compound Library
规格
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
如果上述化合物库无法满足您的需求,您可发送邮件至tech@targetmol.com咨询我们的技术专员,为您量身定制专属化合物库!
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产品描述

  • 1181种与抑郁症相关的化合物,可以用于高通量和高内涵筛选;
  • 部分化合物已上市或已进入临床期;
  • 详细的说明书,化合物结构、靶点信息、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

化合物库定制

TargetMol的化合物可以高度定制! 了解更多

包装和存储

  • 干粉或者DMSO溶液置于带二维码的储存管中,或排列于96孔板/384孔板;
  • 蓝冰运输
获取筛选库化合物信息 (L9860)
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TargetMol Library Books客户使用化合物库发表的文献

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化合物库组成

NF-κB (185)
PI3K (169)
Apoptosis (156)
5-HT Receptor (141)
Autophagy (137)
mTOR (89)
Akt (87)
Dopamine Receptor (84)
NMDAR (70)
AMPK (66)
Endogenous Metabolite (61)
GSK-3 (55)
Reactive Oxygen Species (48)
iGluR (41)
GABA Receptor (41)
Adrenergic Receptor (40)
Antibacterial (38)
Monoamine Oxidase (38)
DNA-PK (37)
Serotonin Transporter (36)
ERK (31)
CDK (30)
COX (30)
S6 Kinase (29)
Norepinephrine (29)
MAO (27)
IκB/IKK (27)
p38 MAPK (26)
ATM/ATR (23)
AChR (23)
TNF (22)
GluR (21)
Parasite (21)
PDK (19)
JNK (19)
Histamine Receptor (19)
Potassium Channel (15)
Caspase (15)
P450 (15)
STAT (15)
Mitophagy (15)
HIV Protease (14)
PI4K (13)
Sodium Channel (13)
Influenza Virus (13)
Antifungal (12)
RIP kinase (12)
Calcium Channel (12)
IL Receptor (12)
PKC (11)
Antibiotic (11)
BCL (10)
NO Synthase (10)
PKA (10)
Src (10)
Ferroptosis (10)
MAPK (9)
NOD (9)
NOD-like Receptor (NLR) (9)
Opioid Receptor (9)
Antioxidant (9)
MEK (9)
DNA/RNA Synthesis (9)
PTEN (8)
Casein Kinase (8)
VEGFR (8)
p53 (7)
Lipoxygenase (7)
FLT (7)
Interleukin (7)
MMP (7)
Beta Amyloid (6)
Bcr-Abl (6)
Microtubule Associated (6)
NOS (6)
Dehydrogenase (6)
Chk (6)
PPAR (6)
SIK (6)
ROCK (6)
IRAK (6)
Chloride channel (5)
Histone Demethylase (5)
HDAC (5)
IGF-1R (5)
JAK (5)
PARP (5)
Topoisomerase (5)
HSV (5)
Aurora Kinase (5)
Antiviral (5)
E1/E2/E3 Enzyme (5)
MELK (5)
Mitochondrial Metabolism (5)
ROS (5)
AChE (4)
CaMK (4)
Nrf2 (4)
Epigenetic Reader Domain (4)
Carbonic Anhydrase (4)
Proteasome (4)
Virus Protease (4)
Aryl Hydrocarbon Receptor (4)
Phosphatase (4)
PDGFR (4)
PDE (4)
FAK (4)
Wnt/beta-catenin (4)
TLR (4)
EGFR (3)
SGK (3)
Glucosidase (3)
Melatonin Receptor (3)
FGFR (3)
Prostaglandin Receptor (3)
PGE Synthase (3)
MT Receptor (3)
P-gp (3)
Sigma receptor (3)
Tyrosinase (3)
Raf (3)
ATPase (3)
Amino Acids and Derivatives (3)
transporter (3)
HIF/HIF Prolyl-Hydroxylase (3)
HIF (3)
PLK (3)
Transferase (3)
Integrin (3)
TRP/TRPV Channel (3)
HCV Protease (3)
TGF-beta/Smad (3)
RAAS (3)
OX Receptor (2)
Adenosine Receptor (2)
Neuropeptide Y Receptor (2)
BACE (2)
Androgen Receptor (2)
c-RET (2)
MRP (2)
Leukotriene Receptor (2)
Rho (2)
Cannabinoid Receptor (2)
HSP (2)
IAP (2)
Anti-infection (2)
Imidazoline Receptor (2)
Guanylate cyclase (2)
HER (2)
GPR (2)
Trk receptor (2)
Tyrosine Kinases (2)
Serine Protease (2)
SARS-CoV (2)
Gamma-secretase (2)
FAAH (2)
Estrogen/progestogen Receptor (2)
Estrogen Receptor/ERR (2)
Drug Metabolite (2)
BCRP (1)
CCR (1)
Tie-2 (1)
PKM (1)
STING (1)
Telomerase (1)
Syk (1)
RSV (1)
Beta-Secretase (1)
Sirtuin (1)
c-Fms (1)
Serine/threonin kinase (1)
RANKL/RANK (1)
Adenosine deaminase (1)
S1P Receptor (1)
Reductase (1)
Reverse Transcriptase (1)
Pim (1)
NADPH-oxidase (1)
AhR (1)
Hck (1)
Liver X Receptor (1)
Kinesin (1)
DNA (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
Immunology/Inflammation related (1)
IFNAR (1)
HMG-CoA Reductase (1)
ATP Citrate Lyase (1)
Histone Methyltransferase (1)
Hedgehog/Smoothened (1)
HBV (1)
LRRK2 (1)
GTPase (1)
GST (1)
DUB (1)
GRK (1)
GlyT (1)
Glutathione Peroxidase (1)
DYRK (1)
Glucokinase (1)
Glucocorticoid Receptor (1)
FXR (1)
Fatty Acid Synthase (1)
LPA Receptor (1)
LTR (1)
Phospholipase (1)
c-Myc (1)
PERK (1)
PAK (1)
cholecystokinin (1)
c-Kit (1)
P2X Receptor (1)
Oxytocin Receptor (1)
ALK (1)
c-Met/HGFR (1)
OCT (1)
NPC1L1 (1)
Aminopeptidase (1)
lysosomal autophagy (1)
NADPH (1)
Myosin (1)
CRFR (1)
Monocarboxylate transporter (1)
Monoamine Transporter (1)
Antifection (1)
MLK (1)
CRISPR/Cas9 (1)
Melanin-concentrating Hormone Receptor (MCHR) (1)
Mdm2 (1)
DAPK (1)
YAP (1)

化合物库信息示例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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