10000+
1000+
22
91
408
Cat. No. | Product Name | ||
---|---|---|---|
L1100 | 蛋白酶抑制剂库 | 344 compounds | |
344 种已知的小分子蛋白酶抑制剂的特有集合,可用于高通量筛选和高内涵筛选; | |||
L9410 | 共价抑制剂库 | 1949 compounds | |
1949 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发; | |||
L1400 | MAPK 抑制剂库 | 367 compounds | |
367 种与MAPK 信号通路相关的生物活性小分子化合物的特有集合,可用于高通量筛选和高内涵筛选; | |||
L2200 | 酪氨酸激酶分子库 | 1033 compounds | |
1033 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L9400 | PPI抑制剂库 | 490 compounds | |
490 种已知活性的 PPI 相关的抑制剂,可用于高通量、高内涵筛选; | |||
L9100 | 磷酸酶抑制剂化合物库 | 80 compounds | |
80 种已知活性的磷酸酶抑制剂的集合,可用于化合物筛选、化学基因组学、药理分析等方面; | |||
L7600 | 趋化因子抑制剂库 | 59 compounds | |
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2000 | 抑制剂库 | 8418 compounds | |
8418 个小分子抑制剂的独特集合,主要用于细胞信号研究、新药筛选、高通量筛选和高内涵筛选; | |||
L1600 | 激酶抑制剂库 | 2720 compounds | |
2720 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L2010 | 高选择性抑制剂库 | 580 compounds | |
xunm种具有高选择性的抑制剂集合 | |||
L3600 | 细胞因子抑制剂库 | 613 compounds | |
613 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体; | |||
L1610 | FDA 上市激酶抑制剂库 | 266 compounds | |
266种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L2300 | 离子通道库 | 946 compounds | |
946 种与离子通道相关的生物活性小分子化合物的特有集合,用于离子通道相关的疾病和药物研究,可用于高通量筛选和高内涵筛选; | |||
L5400 | 抗心血管疾病化合物库 | 1428 compounds | |
1428 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6730 | 抗病毒中药单体化合物库 | 270 compounds | |
270 种具有抗病毒活性的中药单体集合,是药物开发、药理研究的有效工具; | |||
L1110 | 微管靶向化合物库 | 155 compounds | |
155 种靶向微管的分子集合,用于高通量筛选和高内涵筛选; | |||
L6120 | 黄酮类天然产物库 | 477 compounds | |
477 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2520 | 糖代谢化合物库 | 708 compounds | |
708 种糖代谢相关的化合物,可用于高通量和高内涵筛选; | |||
L4700 | 免疫/炎症分子化合物库 | 3483 compounds | |
3483 种具有抗炎症活性的化合物的特有集合,可用于高通量筛选和高内涵筛选; | |||
L9420 | 外泌体相关化合物库 | 80 compounds | |
80 种外泌体相关的化合物,可以用于高通量和高内涵筛选; | |||
L4020 | NO PAINS 化合物库 | 9555 compounds | |
TargetMol NO PAINS 化合物库包含 9555 个剔除了PAINS 的小分子活性化合物,可用于新药研发,信号通路研究,老药新用等研究。 | |||
L6740 | 抗结直肠癌中药单体化合物库 | 386 compounds | |
386 种抗结直肠癌相关的中药单体集合,是药物开发、药理研究的有效工具; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10599 |
BRAF inhibitor
|
Raf | MAPK |
BRAF inhibitor 是B-Raf 抑制剂。 | |||
T2072 |
BET bromodomain inhibitor
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
BET bromodomain inhibitor 是 BET 的一种有效抑制剂。 | |||
T14913 |
CD38 inhibitor 1
|
CD38 | Immunology/Inflammation |
CD38 inhibitor 1 是一种有效的 CD38抑制剂,能够作用于人类的 CD38 (IC50:7.3 nM)和小鼠的 CD38 (IC50:1.9 nM)。 | |||
T15146 |
DNA2 inhibitor C5
|
Others | Others |
DNA2 inhibitor C5 是竞争性特异性的DNA2 核酸酶活性抑制剂(IC50:20 μM)。它能够抑制DNA 依赖性 ATPase、 DNA2 的核酸酶、解旋酶和 DNA 结合活性。它可用于研究奥正癌症。 | |||
T11950 |
MAT2A inhibitor 2
|
Others; Methionine Adenosyltransferase (MAT) | Chromatin/Epigenetic; Others |
MAT2A inhibitor 2 是一种甲硫氨酸腺苷转移酶2A 的抑制剂。 | |||
T15051 |
Dansylamide
|
Others | Others |
Dansylamide 是活性荧光染料,可标记丹磺酰基团,常用于生物化学实验。 | |||
T19356 |
HTBA
|
Others | Others |
HTBA 是一种用于测定尿肌酐的低成本酶促纸基分析试剂 (enz-PAD)。 | |||
T6969 |
Imidacloprid
|
Others | Others |
Imidacloprid 是一种新烟碱类农药,广泛用于控制蔬菜,谷物,茶叶和棉花的害虫。 | |||
T40477 |
Dichlormid
|
Others | Others |
Dichlormid 是一种除草剂剂。它上调 ZmMRP1 和 ZmGST27 的表达并增加 ZmGT1。 | |||
T15140 |
DLinDMA
|
Others | Others |
DLinDMA 是一种稳定的核酸脂质颗粒 (SNALPs) 中的关键脂质成分,是一种可电离的阳离子脂质。它可用于siRNA 递送的研究。 | |||
T5560 |
Dicyclanil
|
Others | Others |
Dicyclanil 是一种化学结构与环丙嗪相似的昆虫生长调节剂。 | |||
T6606 |
Nicaraven
|
Others | Others |
Nicaraven 是新型的、化学合成的羟基自由基清除剂。 | |||
T7421 |
Melperone
|
Others | Others |
Melperone 是一种丁酰苯,是一种具有睡眠诱导作用的抗精神病试剂,常用于研究精神类疾病。 | |||
T9751 |
Transfluthrin
|
Others | Others |
Transfluthrin 是一种挥发性拟除虫菊酯类杀虫剂,针对昆虫电压门控钠通道 (VGSC)。 | |||
T18919 |
Bathophenanthroline
|
Others | Others |
Bathophenanthroline 是一种能够通过染色法测量水,血清和尿液样中铁浓度的试剂。 | |||
T18934 |
Calmagite
|
Others | Others |
Calmagite 是络合指示剂,可用于多种样品中的钙和镁的检测。 | |||
T15352 |
FTBMT
|
GPR | Endocrinology/Hormones; GPCR/G Protein |
FTBMT 是一种选择性的GPR52激动剂(EC50:75 nM),具有抗精神病和促进认知的作用。 | |||
T19821 |
Methoxyfenozide
|
Others | Others |
Methoxyfenozide 是一种二酰基肼类杀虫剂,其与鳞翅类蜕皮激素受体 (EcRs) 结合 (Kd=0.5 nM) 比对二萜 EcRs 结合 (Kd=124 nM) 的选择性高。 | |||
TQ0013 |
BTTAA
|
Others | Others |
BTTAA 是 Cu(I)-稳定配体,能够的有效与泛素 Glu18AzF 反应。 | |||
T13098 |
TBOPP
|
Others | Others |
TBOPP 是DOCK1的选择性抑制剂(IC50:8.4 μM)。它以高亲和力与DOCK1DHR-2 结构域结合 (Kd 为 7.1 μM) ,对多种肿瘤均具有抗肿瘤活性。 | |||
T19561 |
Simetryn
|
Others | Others |
Simetryn 是一种稻田除草剂,可作为一种化学应激源,延缓蝌蚪的生长和发育,而不会破坏甲状腺功能,即使在 96 小时 LC50 值的 1/100 时也是如此。 | |||
T14527 | Benfluralin | ||
Benfluralin 是一种除草剂,是一种农用化学品,可用作芽前除草剂。 用于控制一系列粮食和非粮食作物中的草和其他杂草。 | |||
T14529 |
Bentiromide
|
Others | Others |
Bentiromide 是一种可被胰腺分泌的胰凝乳蛋白酶分解的多肽。Bentiromide 通过胰凝乳蛋白酶功能的体外试验确认胰腺外分泌功能。 | |||
T18981 |
DMA
|
Others | Others |
DMA 是一种荧光试剂 (λex=340 nm, λem=478 nm)。 | |||
T14353 |
Auxinole
|
Others | Others |
Auxinole 是TIR1/AFB 受体植物激素拮抗剂。它可与 TIR1 结合,阻断 TIR1-IAA-Aux/IAA 复合物的形成,抑制 auxin 应答基因的表达。 | |||
T17040 |
Terbutryn
|
Others | Others |
Terbutryn 是选择性除草剂和三嗪化合物,能够被根部和叶子吸收,抑制光合作用的发生。 | |||
T2554 |
Etofibrate
|
Others | Others |
Etofibrate 是烟酸和氯贝酸的醚二醇-1,2 二酯。它是动物和人类中一种有效的降血脂剂。 | |||
T39635 |
Obafistat
|
NADPH | Metabolism |
Obafistat 是醛酮还原酶 AKR1C3 的有效抑制剂,抑制人 AKR1C3 的IC50为 1.2 nM。 | |||
T5161 |
Gadodiamide
|
Others | Others |
Gadodiamide 是一种含钆造影剂,可用于医学成像。 | |||
T15106 |
DFHBI
|
Others | Others |
DFHBI 是类似于绿色荧光蛋白发色团的小分子。 Spinach-DFHBI 复合物在体外和活细胞中都具有明亮的荧光,而pinach 和 DFHBI 在未结合时基本不发荧光。 | |||
T7099 |
Gefarnate
|
Others | Others |
Gefarnate 是一种胃炎和胃溃疡的研究药物,目前也用于研究干眼症。 | |||
T40626 |
Curdlan
|
Others | Others |
Curdlan 是一种多糖,由细菌产生。 | |||
T38585 | Tetrachlorocatechol | Others | Others |
Tetrachlorocatechol (TCC) is a chlorinated catechol compound that serves as a metabolite of pentachlorophenol. It is prominently generated during the chlorobleaching process in pulp production and is commonly detected in effluents from kraft pulp mills [1] [2]. TCC stands out as one of the most highly toxic chlorinated catechols. | |||
T15136 | DiZPK | Others | Others |
DiZPK 是吡咯赖氨酸的类似物,可用作光交联剂。 | |||
T11050 |
Dipyrocetyl
|
Others | Others |
Dipycecetyl 是止痛及抗炎剂。 | |||
T15447 |
Guacetisal
|
Others | Others |
Guacetisal 是从乙酰水杨酸与愈创木酚的酯化反应中提取的,可用于治疗慢性支气管炎的相关研究。 | |||
T19586 |
TOPS
|
Others | Others |
TOPS 是一种高度溶于水的苯胺衍生物,在诊断和生物实验中有广泛运用。 | |||
T40515 |
Metamitron
|
||
Metamitron 是一种光合电子传递链抑制剂,可用作化学稀释剂。 | |||
T38655 |
Trifludimoxazin
|
Others | Others |
Trifludimoxazin 可用作除草剂,是一种原卟啉原氧化酶的抑制剂。 | |||
T22135 |
PPIase-Parvulin Inhibitor
|
Others | Others |
PPIase-Parvulin Inhibitor 是一种抑制剂,可以抑制PPlase Pin1 和Pin4的细胞渗透。 | |||
T5206 |
DAAO inhibitor-1
|
Others | Others |
DAAO inhibitor-1是 D-氨基酸氧化酶抑制剂(IC50:0.12 μM)。 | |||
T40505 | Pendimethalin | Others | Others |
Pendimethalin 是一种特异性除草剂,防除一年生禾本科和某些一年生阔叶杂草。 | |||
T19060 |
SPQ
|
Others | Others |
SPQ 可用于测量膜氯化物传输机制。 | |||
T9416 |
Dansylglycine
|
Others | Others |
Dansylglycine 是一种荧光探针,用于特异性测定髓过氧化物酶和嗜酸性粒细胞过氧化物酶的卤化活性。 | |||
T18913 |
ADOS
|
Others | Others |
ADOS 是一种显色试剂。 | |||
T8455 |
Spinorphin
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Spinorphin 是一种脑非肽降解酶抑制剂,能够抑制氨基肽酶、二肽基氨基肽酶III、血管紧张素转换酶和脑非肽酶。它可用于研究疼痛的缓解。 | |||
T16537 |
Pimonidazole
|
Others | Others |
Pimonidazole 是缺氧标记物,能够与大分子的共价结合或被还原形成还原性代谢物后在缺氧细胞中积累,可用于定性和定量评估肿瘤缺氧。它可用于瘤内缺氧和细胞增殖的补充性研究。 | |||
T19533 |
Pyraclonil
|
Others | Others |
Pyraclonil, a herbicide agent, effectively controls susceptible (S) and multiple-herbicide-resistant (MHR) E. indica populations as it acts as a proporphyrinogen oxidase (PPO) inhibitor. | |||
T5123 |
Pirozadil
|
Others | Others |
Pirozadil 是降血脂药。 | |||
T19353 |
HDAOS
|
Others | Others |
HDAOS 是一种新型Trinder's 试剂,是苯胺衍生物,具有高水溶性,被广泛用于诊断检测和生化试验。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1453 |
Bruceantinol
|
Anti-infection | Microbiology/Virology |
Bruceantinol 是一种quassinol 化合物,分离自Brucea javanica 的 CH3OH 提取物。它能够将系统性寄主植物中灭活。有效的抑制浓度为 10 μM。 | |||
T14961 |
Chrysene
䓛,屈 |
Others | Others |
Chrysene 是高分子量 (HMW) 多环芳烃,有极强的顽固性和致癌性。 | |||
TN2058 |
Persicogenin
|
Anti-infection | Microbiology/Virology |
Persicogenin 是分离自 Rhus retinorrhoea 中,具有抗癌作用。 | |||
TWS1563 |
Incensole
|
Others | Others |
Incensole 是一种 14-membered 二萜类化合物,分离自烯属植物的香精油和乳香树脂中。它能够激活脑中离子通道,并可以缓解焦虑或抑郁,从而显示出抗炎和抗抑郁的特性。 | |||
T6S1676 |
Cimigenoside
|
Others | Others |
Cimigenoside 是升麻属中的一种成分。 | |||
T5777 |
Phaseoloidin
|
Others | Others |
Phaseoloidin 是来自烟草细毛虫的高纯酸苷,有助于植物抵抗鳞翅目草食动物。它能够抑制Manduca sexta 和Spodoptera littoralis 的幼虫生长。它具有抗补体特性。 | |||
T5813 |
BYAKANGELICIN
|
Reductase | Endocrinology/Hormones; Metabolism |
Byakangelicin 是发现于当归根中的一种活性化合物,可作为调节剂,改善各种活性化合物 (Umb,Cur 和 Dox) 的脑积累,增强研究效果。它提高所有PXR 靶基因 (如MDR1) 的表达,并广泛的诱导药物-药物相互作用。它可抑制性激素的作用,可能会增加内源激素的分解代谢。 | |||
T8208 |
androsin
|
Others | Others |
Androsin 分离于印度胡黄连中,具有抗哮喘作用。 | |||
TN1982 |
Neoglycyrol
|
Others | Others |
Neoglycyrol 是分离自甘草的根中的化合物。它是由传统专利药通脉养心丸中筛选得到,具有潜在心肌保护作用。 | |||
T3931 |
Isobavachin
|
Others | Others |
Isobavachin 是一种分离自Psoralea morisiana 中的抗氧化剂,在A 环的8号位置有一个prenyl 基团,具有潜在的促进神经元的分化和其蛋白异戊烯化作用。 | |||
T19431 |
Moluccanin
|
Others | Others |
Moluccanin 是来自 Aleurites moluccana 的香豆素类。 | |||
T3873 |
griffonilide
|
Others | Others |
Griffonilide 是一种提取自Semiaquilegia adoxoides 根中的丁烯内酯类化合物,常与紫草甙一起出现。它是一种传统抗癌药草。 | |||
T8077 |
Dihydrojasmone
|
Others | Others |
Dihydrojasmone 是一种重要的香料成分,是佛手柑油的成分。 | |||
T5S1331 |
Herbacetin
|
c-Met/HGFR; Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
Herbacetin 是一种亚麻籽中的天然类黄酮,具有多种药理活性,如抗氧化、抗炎、抗癌作用。 它是鸟氨酸脱羧酶Ornithine decarboxylase (ODC)变构抑制剂,能够直接与 ODC 上的 Asp44,Asp243 和 Glu384 结合。其中鸟氨酸脱羧酶是多胺生物合成中的限速酶。 | |||
TN6723 |
Lactiflorin
|
Others | Others |
Lactiflorin 是一种具有肾脏保护作用的单萜苷。 | |||
T14291 |
Anisindione
|
Others | Others |
Anisindione 是合成的抗凝血剂,对活性促凝因子II,VII,IX 和X 的形成具有抑制作用。 | |||
T3S0693 |
Blinin
|
Others | Others |
Blinin 是一种二萜,分离自植物 Conyza blinii 中。 | |||
T8195 |
Lotusine
|
Others | Others |
Lotusine 是一种提取自Nelumbo nucifera Gaertn 的绿色种胚中的纯生物碱。它能够作用于心肌中动作电位及心脏浦肯野纤维缓慢内向电流。 | |||
TN1028 |
Militarine
|
Others | Others |
Militarine 是一种糖苷化合物,分离自 Bletilla striata,能够抑制植物生长。 | |||
T39049 |
Yubeinine
|
Others | Others |
Yubeinine 是一种生物碱类天然产物,可以起到气管松弛作用。 | |||
T8194 |
Isoflavone
|
Antioxidant | oxidation-reduction |
Isoflavone 是大豆植物雌激素和生物活性成分,存在于大豆、青豆、花生、鹰嘴豆和苜蓿等几种重要的豆类作物中。 | |||
TN1455 |
Bryodulcosigenin
|
Immunology/Inflammation related | Immunology/Inflammation |
Bryodulcosigenin 是一种 Bryoniadioica 根的提取物,具有抗炎活性。 | |||
TN1785 |
Isomagnolone
|
Others | Others |
Isomagnolone 是一种分离自八角茴香中的天然产物,具有抗炎作用。 | |||
TN3548 |
Bulleyanin
|
Others | Others |
Bulleyanin 是从 isodon species (Labiatae) 中分离出来的一种物质。 | |||
T5747 |
ISOBERGAPTEN
|
Others | Others |
Isobergapten 是一种化感抑制剂,分离自Hevacleum laciniatum 种子。 | |||
T3S2019 |
Lathyrol
|
Others | Others |
Lathyrol 是一种具有抗癌功能的天然产物。 | |||
TN6712 |
yibeissine
|
Others | Others |
Yibeissine 是一种甾体生物碱,分离自贝母球茎中。 | |||
T13350 |
Wushanicaritin
|
Others | Others |
Wushanicaritin 在 DPPH 自由基清除活性测试中显示出显著的抗氧化活性 ,其IC50值为35.3 μM,具有抗肿瘤作用和抗炎活性。 | |||
TN1833 |
Karacoline
|
NF-κB | NF-κB |
Karacoline 是发现于植物Aconitum kusnezoffii 中的一种二萜生物碱,通过 NF-κB 信号通路,抑制椎间盘退变中细胞外基质的降解。 | |||
T6S2252 |
Sweroside
|
Others | Others |
Sweroside 是分离自Lonicera japonica 中,具有细胞保护、抗骨质疏松和保护肝脏活性。 | |||
T16943 |
Stigmastanol
|
Endogenous Metabolite | Metabolism |
Stigmastanol 是分离自Hypericum riparium 的 6-氨基衍生物。Hypericum riparium 是属于杜仲科的药用植物。 | |||
T3S1850 |
Bayogenin
|
Others | Others |
Bayogenin 是紫花苜蓿皂苷,一定程度上能够抑制糖原磷酸化酶的活性。 | |||
T3S1729 |
Dihydrolycorine
|
Others | Others |
Dihydrolycorine 是分离自Lycoris radiate 草药中,是一种真核细胞中蛋白质合成的抑制剂。 | |||
T5789 |
XYLOTRIOSE
|
Others | Others |
Xylotriose 是双歧杆菌促生因子,是天然的低聚木糖。 | |||
T8169 |
Decursinol
|
Others | Others |
Decursinol 是一种分离自Angelica gigas 的根中的、口服具有活性的抗伤害药物。它具有抗肿瘤和抗转移作用。 | |||
T8203 |
Gentianose
|
Others | Others |
Gentianose 是一种碳水化合储备物,来源于多年生黄龙胆贮藏根中。 | |||
TQ0096 |
Scabertopin
|
Others | Others |
Scabertopin 是一种从地胆草中分离得到倍半萜内酯,具有抗癌和抑菌活性。 | |||
TN1002 |
Blumeatin
|
ROS | Immunology/Inflammation |
Blumeatin 是从Blumea balsamiferaDC 中分离得到,对 CCl4 和硫代乙酰胺 (TAA) 所致的肝损伤表现出保护活性。 | |||
T7032 |
Eupatorin
|
Others; P450 | Metabolism; Others |
Eupatorin 是天然存在的黄酮,可捕获 G2-M 细胞周期,激活多个 caspase、细胞色素 C 的释放、多聚 (ADP-核糖) 聚合酶的裂解,促使凋亡细胞死亡。 | |||
Fr13711 |
Tropinone
|
Others | Others |
Tropinone 是一种可用作合成 Atropine 中间体的生物碱。 | |||
TN1829 |
Kakkalide
|
Dehydrogenase | Metabolism |
Kakkalide 是提取自葛根花中的一种异黄酮。它可以抑制活性氧相关炎症,并改善内皮细胞胰岛素抵抗作用。 | |||
TJS0851 |
Plantagoside
|
Others | Others |
Plantagoside 是α-mannosidase 的非竞争性特异性抑制剂(IC50:5 μM),分离自Plantago asiatica 种子中。 | |||
T8212 |
Dichotomitin
|
Others | Others |
Dichotomitin 是一种提取自Belamcanda chinensis 根茎中的异黄酮。 | |||
TN1111 |
Arnidiol
|
Immunology/Inflammation related | Immunology/Inflammation |
Arnidiol 是一种五环三萜烯,从Barleria Longiflora LinnF. 中提取得到。 | |||
TN2197 |
Secoisolariciresinol
|
TNF | Apoptosis |
Secoisolariciresinol 是一种属于苯丙素类的木脂素。 | |||
T2O2770 |
Agarotetrol
|
Others | Others |
Agarotetrol 是一种色酮衍生物,从沉香中分离得到。 | |||
TN1984 |
Neoisoliquiritin
|
Others | Others |
Neoisoliquiritin 是一种提取自甘草中的活性物质。 | |||
TN1075 |
Adynerin
|
Others | Others |
Adynerin 是一种发现于夹竹桃中的天然类固醇。 | |||
TN1800 |
Isosakuranin
|
Others | Others |
Isosakuranin 是一种提取自Paliurus ramosissimus 果实中的天然产物。 | |||
TN1137 |
Isobutylshikonin
|
Others | Others |
Isobutylshikonin 是分离自Lithospermum canescens 毛状根培养的一种紫草素色素。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04815 |
C1 inhibitor Protein, Rat, Recombinant (His)
serpin peptidase inhibitor, clade G (C1 inhibit... |
Rat | HEK293 |
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides ... | |||
TMPH-00520 |
Host-nuclease inhibitor protein gam Protein, Enterobacteria phage lambda, Recombinant (His & Myc)
|
Escherichia phage lambda | E. coli |
Binds to host RecBCD nuclease and inhibits it thereby protecting the viral DNA against recBCD mediated degradation. | |||
TMPH-02788 |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His)
|
Mouse | E. coli |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPH-02787 |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His)
|
Mouse | Yeast |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His) is expressed in Yeast. | |||
TMPH-03528 |
Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc)
chp,Chemotaxis inhibitory protein,CHIPS |
Staphylococcus aureus | E. coli |
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. | |||
TMPH-03529 |
Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)
CHIPS,Chemotaxis inhibitory protein,chp |
Staphylococcus aureus | Yeast |
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. | |||
TMPY-01183 |
C1 inhibitor Protein, Human, Recombinant (His)
serpin peptidase inhibitor, clade G (C1 inhibit... |
Human | HEK293 |
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides ... | |||
TMPH-00554 |
Trypsin inhibitor DE-3 Protein, Erythrina caffra, Recombinant (His)
|
Erythrina caffra | Yeast |
Inhibition of trypsin. | |||
TMPY-04508 |
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc)
insulin-like growth factor binding protein 7,Mac25,AGM,Fstl2 |
Mouse | HEK293 |
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have bee... | |||
TMPY-02533 |
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His)
insulin-like growth factor binding protein 7,PSF,IGFBP-7,FST... |
Human | HEK293 |
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have bee... | |||
TMPY-02295 |
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc)
IGFBP-7,IGFBPRP1,IBP-7,TAF,FSTL2,PSF,insulin-like growth fac... |
Human | HEK293 |
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have bee... | |||
TMPJ-00779 |
TNF alpha Protein, Rabbit, Recombinant
TNF-a,Tumor Necrosis Factor,TNF-α,TNF α,Cachectin,肿瘤坏死因子,Tum... |
Rabbit | E. coli |
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other ... | |||
TMPY-04645 |
TL1A Protein, Human, Recombinant (hFc)
TL1,tumor necrosis factor (ligand) superfamily, member 15,TL... |
Human | HEK293 |
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. TL1A is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It mediates activation of NF-kappa-B. It also inhibits vascular endothelial growth and angiogenesis (in vitro). TL1A promotes ac... | |||
TMPJ-00603 |
TL1A Protein, Mouse, Recombinant
TNFSF15,Tumor Necrosis Factor Ligand Superfamily Member 15,V... |
Mouse | E. coli |
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ... | |||
TMPY-02647 |
IFNAR1 Protein, Human, Recombinant (His)
interferon (alpha, beta and omega) receptor 1,IFN-α-REC,IFRC... |
Human | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Tyk2 slows down IFNAR1 degradation and that this is due, at least in part, to inhibition of IFNAR1 endocytosis. Mutant versions of IFNAR... | |||
TMPY-01009 |
TGFBI Protein, Human, Recombinant (His)
CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth factor, be... |
Human | HEK293 |
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys... | |||
TMPY-00586 |
CLEC-2 Protein, Mouse, Recombinant (hFc)
1810061I13Rik,Clec2,C-type lectin domain family 1, member B,... |
Mouse | HEK293 |
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and... | |||
TMPY-00875 |
Leptin Protein, Human, Recombinant
OBS,leptin,OB,LEPD |
Human | E. coli |
Leptin is one of the most important hormones secreted by adipocytes, as an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine, and pro-inflammatory immune responses. The circulating leptin levels serve as a gauge of energy stores, thereby directing the regulation of energy homeostasis, neuroendocrine function, and metabolism. Recent studies suggest that leptin is physiologically more important as an indicator of energy deficienc... | |||
TMPY-03072 |
IFN-omega Protein, Human, Recombinant (His)
IFN-ω,IFN-ω 1,interferon omega-1,IFNW1,interferon ω-1,interf... |
Human | HEK293 |
IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide sequence. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type II IFN and is specific for the type II IFN receptor. Human IFN-ω, was identified by three independent groups in 1985 and is structurally related to IFN-α and -β.... | |||
TMPY-01055 |
IL-4R Protein, Human, Recombinant (His)
interleukin 4 receptor,IL4RA,IL4R,CD124,IL-4RA |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ... | |||
TMPY-05277 |
IL-4R Protein, Human, Recombinant (hFc)
IL4R,IL4RA,CD124,IL-4RA,interleukin 4 receptor |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ... | |||
TMPY-01829 |
CD83 Protein, Human, Recombinant (His)
BL11,HB15,CD83 molecule |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... | |||
TMPY-02019 |
CD59 Protein, Human, Recombinant (His)
MIN2,MAC-IP,G344,EL32,FLJ92039,HRF-20,EJ30,HRF20,MSK21,MGC23... |
Human | HEK293 |
CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assemb... | |||
TMPY-02031 |
B7-H3 Protein, Human, Recombinant (His)
CD276 molecule,B7-H3,4Ig-B7-H3,B7RP-2,B7H3 |
Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally relat... | |||
TMPY-01429 |
RELT/TNFRSF19L Protein, Human, Recombinant (His)
TRLT,TNFRSF19L,RELT tumor necrosis factor receptor |
Human | HEK293 |
Receptor expressed in lymphoid tissues (RELT), also known as tumor necrosis factor receptor superfamily, member 19-like (TNFRSF19L), is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1. RELT/TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. REL... | |||
TMPY-02827 |
IFN gamma Protein, Rat, Recombinant (hFc)
interferon, γ,干扰素,interferon, gamma,IFN γ |
Rat | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-01714 |
IFN gamma Protein, Human, Recombinant
IFI,interferon, γ,IFN γ,IFG,IFN gamma,interferon, gamma,干扰素,... |
Human | CHO |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-06983 |
IFN gamma Protein, Human, Recombinant (E. coli)
Interferon Gamma,IFN γ,IFN gamma,IFG,IFI,干扰素,Interferon γ |
Human | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-04262 |
B7-H3 Protein, Human, Recombinant (His), Biotinylated
B7H3,4Ig-B7-H3,CD276 molecule,B7RP-2,B7-H3 |
Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally relat... | |||
TMPY-04064 |
B7-H3 Protein, Mouse, Recombinant (His)
6030411F23Rik,B7RP-2,B7h3,CD276 molecule,AU016588 |
Mouse | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally relat... | |||
TMPY-05641 |
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
4Ig-B7-H3,B7-H3,B7H3,CD276 molecule,B7RP-2 |
Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally relat... | |||
TMPY-03356 |
IFN gamma Protein, Mouse, Recombinant
IFN γ,interferon, γ,interferon, gamma,Ifg,IFN-g,干扰素 |
Mouse | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-01442 |
DMBT1 Protein, Human, Recombinant (His)
GP340,deleted in malignant brain tumors 1,muclin |
Human | HEK293 |
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo... | |||
TMPY-02118 |
IGFBP-6 Protein, Mouse, Recombinant (His)
IGFBP-6,insulin-like growth factor binding protein 6 |
Mouse | HEK293 |
Insulin-like growth factor-binding protein 6 (IGFBP6) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) bindin... | |||
TMPY-03670 |
PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His)
CD274 molecule |
Cynomolgus,Rhesus | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 fa... | |||
TMPY-05208 |
PD-L1 Protein, Human, Recombinant
CD274 molecule,PDCD1L1,PD-L1,PDL1,PDCD1LG1,B7H1,B7-H,B7-H1 |
Human | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 fa... | |||
TMPY-01155 |
PD-L1 Protein, Mouse, Recombinant (His)
Pdcd1l1,CD274 molecule,B7h1,A530045L16Rik,Pdl1,Pdcd1lg1 |
Mouse | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 fa... | |||
TMPY-04774 |
ALK-2/ACVR1 Protein, Human, Recombinant (His)
TSRI,ACVRLK2,FOP,activin A receptor, type I,ACTRI,ACVR1A,SKR... |
Human | Baculovirus-Insect Cells |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been demonstrated that ALK-2 forms complex with either the BMP-2/7-bound BMPR-II or ACVR2A /ACVR2B. ALK-1 and ALK-2 presenting in the yeast Saccharomyces cerevisiae are two haspin homologues. Both ALK-1 and ALK-2 exhibit a weak auto-kinase activity in vitro, and are phosphoproteins i... | |||
TMPY-00237 |
PD-L1 Protein, Canine, Recombinant (hFc)
CD274 molecule |
Canine | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 fa... | |||
TMPY-00836 |
IGFBP-4 Protein, Human, Recombinant (His)
HT29-IGFBP,IBP4,BP-4,IGFBP-4,insulin-like growth factor bind... |
Human | HEK293 |
Insulin-like growth factor-binding protein 4 (IGFBP-4) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) bindi... | |||
TMPY-03802 |
IL-17F Protein, Human, Recombinant (aa 31-163)
ML1,ML-1,IL-17F,interleukin 17F,CANDF6 |
Human | E. coli |
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with allergic responses. IL-17F is expressed by activated T cells and was expressed only in activated CD4+ T cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines, including IL6 and IL8. This cytokine is also found to inhibit the an... | |||
TMPY-04345 |
PD-L1 Protein, Rat, Recombinant (His)
CD274 molecule |
Rat | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 fa... | |||
TMPY-04343 |
PD-L1 Protein, Human, Recombinant (His)
PDL1,B7-H,B7H1,PDCD1LG1,CD274 molecule,PD-L1,PDCD1L1,B7-H1 |
Human | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 fa... | |||
TMPY-04949 |
PD-L1 Protein, Human, Recombinant (His), Biotinylated
PDCD1LG1,B7H1,PD-L1,B7-H1,B7-H,CD274 molecule,PDL1,PDCD1L1 |
Human | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 fa... | |||
TMPY-04548 |
CDK4 Protein, Human, Recombinant (GST)
CMM3,PSK-J3,cyclin-dependent kinase 4 |
Human | Baculovirus-Insect Cells |
CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of CDK4 is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). CDK4 was shown to be responsible for the phosphorylation of retinoblastoma gene product. CDK4 is the ser... | |||
TMPY-00853 |
IL-1RA Protein, Human, Recombinant
DIRA,IL1RA,interleukin 1 receptor antagonist,ICIL-1RA,MVCD4,... |
Human | E. coli |
Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of this protein-encoding gene is reported to be associated with an increased risk of osteoporotic fractures and gastric cancer. IL-1RA/IL1RN may inhibit the activity of IL-1 by binding to... | |||
TMPY-01928 |
IL-18 Protein, Rhesus, Recombinant (His)
白细胞介素,interleukin 18,白介素 |
Rhesus | E. coli |
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its bi... | |||
TMPY-03273 |
IL-18 Protein, Mouse, Recombinant
interleukin 18,白细胞介素,白介素,Il-18,Igif |
Mouse | E. coli |
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its bi... | |||
TMPY-00277 |
IL-18 Protein, Human, Recombinant
IGIF,IL-18,IL1F4,IL-1g,Interleukin 18 |
Human | E. coli |
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its bi... | |||
TMPY-01278 |
Apolipoprotein H/APOH Protein, Human, Recombinant (His)
BG,apolipoprotein H (beta-2-glycoprotein I),B2G1,apolipoprot... |
Human | HEK293 |
Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. It is an essential cofactor for the binding of certain antiphospholipid antibodies (APA) to anionic phospholipid. APOH binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. APOH may prevent activation of the intrinsi... | |||
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