|
TMPY-04815
|
C1 inhibitor Protein, Rat, Recombinant (His)
serpin peptidase inhibitor, clade G (C1 inhibit...
|
Rat
|
HEK293 Cells
|
|
C1 inhibitor Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.7 kDa and the accession number is A6HMR4. |
|
TMPH-03529
|
Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)
CHIPS,Chemotaxis inhibitory protein,chp
|
Staphylococcus aureus
|
P. pastoris (Yeast)
|
|
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Re... |
|
TMPH-03528
|
Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc)
chp,Chemotaxis inhibitory protein,CHIPS
|
Staphylococcus aureus
|
E. coli
|
|
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS... |
|
TMPY-01183
|
C1 inhibitor Protein, Human, Recombinant (His)
serpin peptidase inhibitor, clade G (C1 inhibit...
|
Human
|
HEK293 Cells
|
|
C1 inhibitor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.3 kDa and the accession number is E9KL26. |
|
TMPH-00554
|
Trypsin inhibitor DE-3 Protein, Erythrina caffra, Recombinant (His)
Trypsin inhibitor DE-3
|
Erythrina caffra
|
P. pastoris (Yeast)
|
|
Inhibition of trypsin. |
|
TMPH-02787
|
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His)
Anti-Muellerian hormone,Amh,Muellerian-inhibiting s...
|
Mouse
|
P. pastoris (Yeast)
|
|
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His) is expressed in Yeast. |
|
TMPH-00520
|
Host-nuclease inhibitor protein gam Protein, Enterobacteria phage lambda, Recombinant (His & Myc)
Host-nuclease inhibitor protein gam,gam
|
Escherichia phage lambda
|
E. coli
|
|
Binds to host RecBCD nuclease and inhibits it thereby protecting the viral DNA against recBCD mediated degradation. |
|
TMPH-02788
|
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His)
Amh,Anti-Muellerian hormone,Muellerian-inhibiting s...
|
Mouse
|
E. coli
|
|
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli. |
|
TMPJ-00779
|
TNF alpha Protein, Rabbit, Recombinant
TNF-a,Tumor Necrosis Factor,TNF-α,TNF α,Cachectin,肿瘤坏死因子,Tum...
|
Rabbit
|
E. coli
|
|
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other ... |
|
TMPJ-00603
|
TL1A/TNFSF15 Protein, Mouse, Recombinant
TNFSF15,Tumor Necrosis Factor Ligand Superfamily Member 15,V...
|
Mouse
|
E. coli
|
|
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ... |
|
TMPY-01009
|
TGFBI Protein, Human, Recombinant (His)
CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth factor, be...
|
Human
|
HEK293 Cells
|
|
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys... |
|
TMPY-01442
|
DMBT1 Protein, Human, Recombinant (His)
GP340,deleted in malignant brain tumors 1,muclin
|
Human
|
HEK293 Cells
|
|
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo... |
|
TMPY-04548
|
CDK4 Protein, Human, Recombinant (GST)
CMM3,PSK-J3,cyclin-dependent kinase 4
|
Human
|
Baculovirus Insect Cells
|
|
CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of CDK4 is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). CDK4 was shown to be responsible for the phosphorylation of retinoblastoma gene product. CDK4 is the ser... |
|
TMPH-02268
|
AGTR2 Protein, Human, Recombinant (His & SUMO)
AT2 receptor,Angiotensin II type-2 receptor,Type-2 angiotens...
|
Human
|
E. coli
|
|
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. |
|
TMPH-01589
|
KIR2DS3 Protein, Human, Recombinant (His)
KIR2DS3,Natural killer-associated transcript 7,Killer cell i...
|
Human
|
P. pastoris (Yeast)
|
|
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. |
|
TMPH-01588
|
KIR2DS1 Protein, Human, Recombinant (His)
KIR2DS1,CD158 antigen-like family member H,Killer cell immun...
|
Human
|
P. pastoris (Yeast)
|
|
Receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Does not inhibit the activity of NK cells. |
|
TMPH-02213
|
Tomoregulin-1 Protein, Human, Recombinant (E. coli, His)
H7365,TMEFF1,Tomoregulin-1,Transmembrane protein with EGF-li...
|
Human
|
E. coli
|
|
May inhibit NODAL and BMP signaling during neural patterning. May be a tumor suppressor in brain cancers. |
|
TMPH-00546
|
Epstein-Barr virus (strain GD1) BARF1 Protein (His)
33 kDa early protein,BARF1,p33,Secreted protein BARF1
|
EBV
|
E. coli
|
|
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro. |
|
TMPH-00892
|
A1AR Protein, Human, Recombinant (His)
Adenosine receptor A1,ADORA1
|
Human
|
E. coli
|
|
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. A1AR Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 39.3 kDa and the accession number is P30542. |
|
TMPH-00819
|
Pro-hevein Protein, Hevea brasiliensis, Recombinant (His)
HEV1,Pro-hevein,Major hevein
|
Hevea brasiliensis
|
E. coli
|
|
N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin. Can inhibit fungal growth. Pro-hevein Protein, Hevea brasiliensis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.1 kDa and the accession number is P02877. |
|
TMPY-01363
|
Serpin A11 Protein, Mouse, Recombinant (His)
serpin peptidase inhibitor, clade A (α-1 antiprotei...
|
Mouse
|
HEK293 Cells
|
|
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhi... |
|
TMPH-00547
|
Epstein-Barr virus (strain B95-8) BARF1 Protein (His & Myc)
33 kDa early protein,p33,Secreted protein BARF1
|
EBV
|
E. coli
|
|
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro. |
|
TMPH-01201
|
DRD2 Protein, Human, Recombinant (His & Myc)
Dopamine D2 receptor,D(2) dopamine receptor,DRD2
|
Human
|
E. coli
|
|
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5. |
|
TMPH-01590
|
KIR2DS3 Protein, Human, Recombinant (His & Myc)
KIR2DS3,Natural killer-associated transcript 7,Killer cell i...
|
Human
|
E. coli
|
|
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. KIR2DS3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.7 kDa and the accession number is Q14952. |
|
TMPH-01587
|
KIR2DS1 Protein, Human, Recombinant (E. coli, His)
CD158 antigen-like family member H,MHC class I NK cell recep...
|
Human
|
E. coli
|
|
Receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Does not inhibit the activity of NK cells. KIR2DS1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.8 kDa and the accession number is Q14954. |
|
TMPY-01855
|
Serpin A10 Protein, Mouse, Recombinant (His)
serpin peptidase inhibitor, clade A (alpha-1 antipr...
|
Mouse
|
HEK293 Cells
|
|
Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPINA1 / Serpin-A1 inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because ... |
|
TMPH-00430
|
VxXIIC Protein, Conus vexillum, Recombinant (His & Myc & SUMO)
Alpha-conotoxin VxXXC,VxXIIC
|
Conus vexillum
|
E. coli
|
|
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes. VxXXA and VxXXB inhibit alpha-7/CHRNA7 and alpha-3-beta-2/CHRNA3-CHRNB2 nAChR more efficiently than VxXXC. VxXXB is the most effective at inhibiting alpha-4-beta-2/CHRNA4-CHRNB2 nAChR, followed by VxXXC and VxXXA. VxXII... |
|
TMPH-02408
|
SPI Protein, Lentinula edodes, Recombinant (His)
Serine protease inhibitor
|
Lentinula edodes
|
E. coli
|
|
Serine protease inhibitor. Active against beta-trypsin and alpha-chymotrypsin with dissociation constants of 0.35 nM and 40 nM respectively. Inhibits factor XIa, but not other enzymes involved in coagulation and fibrinolysis. Does not inhibit subtilisin, lysyl endopeptidase, arginyl endopeptidase or papain. |
|
TMPK-01480
|
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
IAP4,Survivin,API4,BIRC5,MHC,MHC I,EPR-1,survivin variant 3 ...
|
Human
|
HEK293 Cells
|
|
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target. |
|
TMPH-02358
|
Influenza B (strain B/Lee/1940) Non-structural protein 1 (His)
NS1A,Non-structural protein 1,NS
|
Influenza B
|
E. coli
|
|
Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins. Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response. Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR. Also binds poly(A) and U6 snRNA. |
|
TMPH-02693
|
GNAI2 Protein, Mouse, Recombinant (His)
Guanine nucleotide-binding protein G(i) subunit alpha-2,Gnai...
|
Mouse
|
E. coli
|
|
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. |
|
TMPY-03498
|
ING4 Protein, Human, Recombinant (His)
inhibitor of growth family, member 4,p29ING4,my036
|
Human
|
E. coli
|
|
ING4 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. ING4 contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. ING4 protein can bind TP53 and EP3/p3, a component of the histone acetyltransferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. ING4 is a component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activi... |
|
TMPJ-00697
|
NOL3 Protein, Human, Recombinant (GST)
Nop30,Myp,NOP,Apoptosis Repressor With CARD,Nucleolar Protei...
|
Human
|
E. coli
|
|
Nucleolar Protein 3 is encoded by NOL3 gene; multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in RNA splicing.Isoform 2 may inhibit apoptosis.It has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. |
|
TMPK-01517
|
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)
survivin variant 3 alpha,MHC I,BIRC5,EPR-1,IAP4,Survivin,API...
|
Human
|
HEK293 Cells
|
|
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target. |
|
TMPH-01654
|
MAGEA1 Protein, Human, Recombinant (His)
Antigen MZ2-E,MAGE-1 antigen,Cancer/testis antigen 1.1,Melan...
|
Human
|
P. pastoris (Yeast)
|
|
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. MAGEA1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 36.3 kDa and the accession number... |
|
TMPH-03315
|
IGFBP-1 Protein, Rat, Recombinant
Insulin-like growth factor-binding protein 1,Igfbp1
|
Rat
|
E. coli
|
|
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. IGFBP-1 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26.9 kDa and the accession number is P21743. |
|
TMPH-00837
|
BjaIT Protein, Hottentotta judaicus, Recombinant (His & Myc)
Alpha-insect toxin BjaIT,Bj-alpha-IT
|
Hottentotta judaicus
|
E. coli
|
|
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against insects (para/tipE). BjaIT Protein, Hottentotta judaicus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.4 kDa and the accession number is Q56TT9. |
|
TMPK-01516
|
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)
IAP4,survivin variant 3 alpha,BIRC5,Survivin,EPR-1,API4,MHC ...
|
Human
|
HEK293 Cells
|
|
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target. |
|
TMPY-02712
|
Serpin B3 Protein, Human, Recombinant (His)
T4-A,HsT1196,serpin peptidase inhibitor, clade B (o...
|
Human
|
Baculovirus Insect Cells
|
|
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be... |
|
TMPH-02188
|
Tenascin-X Protein, Human, Recombinant (His & Myc)
TNXB,Tenascin-X,Hexabrachion-like protein
|
Human
|
E. coli
|
|
Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors. Tenascin-X Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 81.5 kDa and the accession number is P22105. |
|
TMPY-01841
|
Serpin I2 Protein, Human, Recombinant (His)
PI14,TSA2004,PANCPIN,MEPI,Serpin I2,serpin peptidase inh...
|
Human
|
HEK293 Cells
|
|
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chy... |
|
TMPY-01843
|
SEMA6A Protein, Human, Recombinant (His)
HT018,VIA,sema domain, transmembrane domain (TM), and cytopl...
|
Human
|
HEK293 Cells
|
|
SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SEMA6A may be a potential prognostic biomarker in the treatment of GBM. Among different semaphorins tested by reverse transcriptase-polymerase chain reaction in human immune cells, the expression of class 6 transmembrane semaphorin SEMA6A was restricted to dendritic cells (DCs). |
|
TMPY-04417
|
DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)
DAPK,death-associated protein kinase 1,ROCO3
|
Human
|
Baculovirus Insect Cells
|
|
Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK1 contains tenANK repeats, onedeath domain and oneprotein kinase domain. DAPK1 is a calcium / calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. DAPK1 gene is a candidate tumor suppressor (TSG) and the abnormal methylation of DAPK1 g... |
|
TMPH-01672
|
Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc)
M,Matrix protein,M protein
|
HMPV
|
E. coli
|
|
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer. |
|
TMPH-01673
|
Human metapneumovirus (strain CAN97-83) Matrix protein (His)
M,Matrix protein,M protein
|
HMPV
|
P. pastoris (Yeast)
|
|
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer. |
|
TMPK-00610
|
SIRP alpha V2 Protein, Human, Recombinant (hFc)
PTPNS1,MYD-1,MFR,SHPS1,SIRPalpha2,SIRPα2,SIRPA,SIRP α V2/CD1...
|
Human
|
HEK293 Cells
|
|
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.... |
|
TMPH-02650
|
FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO)
Fas apoptotic inhibitory molecule 3,Immunoglobulin ...
|
Mouse
|
E. coli
|
|
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. |
|
TMPJ-01016
|
INHBC Protein, Human, Recombinant (N-His)
Activin Beta-C Chain,INHBC,Inhibin β C Chain,Activin β-C Cha...
|
Human
|
E. coli
|
|
Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins,Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary... |
|
TMPK-00489
|
TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
TNFSF15,TNF superfamily member 15,TL1,VEGI192A,TL1A,VEGI-251...
|
Cynomolgus,Rhesus
|
HEK293 Cells
|
|
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weigh... |
|
TMPJ-01313
|
HIV-1 gp120 Protein (His)
Envelope glycoprotein gp120,Surface protein gp120,Glycoprote...
|
HIV
|
HEK293 Cells
|
|
Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequ... |
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