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IBTP is a lipophilic cation that is accumulated in mitochondria and forms stable thioether adducts in a thiol-specific manner. As a result, mitochondrial proteins that have changed thiol redox state following oxidative stress are selectively tagged with IBTP and can be separated by two-dimensional electrophoresis and isolated. IBTP-tagged proteins can also be evaluated by immunoblotting using an antibody directed against the triphenylphosphonium moiety of the IBTP molecule. IBTP has also been used as a mitochondria-targeted soft electrophile to inhibit mitochondrial oxidative phosphorylation.
IBTP is a lipophilic cation that is accumulated in mitochondria and forms stable thioether adducts in a thiol-specific manner. As a result, mitochondrial proteins that have changed thiol redox state following oxidative stress are selectively tagged with IBTP and can be separated by two-dimensional electrophoresis and isolated. IBTP-tagged proteins can also be evaluated by immunoblotting using an antibody directed against the triphenylphosphonium moiety of the IBTP molecule. IBTP has also been used as a mitochondria-targeted soft electrophile to inhibit mitochondrial oxidative phosphorylation.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥ 1,290 | 35日内发货 | |
| 10 mg | ¥ 2,450 | 35日内发货 | |
| 25 mg | ¥ 5,680 | 35日内发货 |
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该分子属于定制产品。TargetMol拥有优秀的合成团队,经验和能力,可以为您提供高性价比的产品。 但由于客观因素,研发中会存在小概率合成不成功的情况,还请理解,
如您有任何问题,欢迎咨询,我们将竭诚为您服务。| 产品描述 | IBTP is a lipophilic cation that is accumulated in mitochondria and forms stable thioether adducts in a thiol-specific manner. As a result, mitochondrial proteins that have changed thiol redox state following oxidative stress are selectively tagged with IBTP and can be separated by two-dimensional electrophoresis and isolated. IBTP-tagged proteins can also be evaluated by immunoblotting using an antibody directed against the triphenylphosphonium moiety of the IBTP molecule. IBTP has also been used as a mitochondria-targeted soft electrophile to inhibit mitochondrial oxidative phosphorylation. |
| 分子量 | 572.209 |
| 分子式 | C22H23I2P |
| CAS No. | 159085-21-9 |
| Smiles | [I-].ICCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1 |
| 密度 | no data available |
| 存储 | |
| 溶解度信息 | DMSO: Soluble |
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