6673
1000+
34
56
663
Cat. No. | Product Name | ||
---|---|---|---|
L2550 | 谷氨酰胺代谢化合物库 | 565 compounds | |
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选; | |||
L4100 | TGF-β/Smad靶点化合物库 | 184 compounds | |
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L7300 | 钾通道分子库 | 152 compounds | |
152 种钾通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6740 | 抗结直肠癌中药单体化合物库 | 382 compounds | |
382 种抗结直肠癌相关的中药单体集合,是药物开发、药理研究的有效工具; | |||
L2194 | 抗结直肠癌化合物库 | 1545 compounds | |
1545 种与结直肠癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L2130 | 抗癌细胞代谢库 | 1268 compounds | |
1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合,用于肿瘤相关的研究以及抗肿瘤药物的筛选,用于高通量、高内涵筛选; | |||
L5200 | 抗代谢疾病化合物库 | 1544 compounds | |
1544 个代谢疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6001 | Mini真菌代谢天然产物筛选库 | Inquiry | |
L3700 | JAK-STAT 化合物库 | 252 compounds | |
252 个 JAK/STAT 靶点相关的小分子化合物的独特集合,用于高通量、高内涵筛选; | |||
L2700 | 肾上腺素能受体化合物库 | 193 compounds | |
193 种特异靶向肾上腺素受体的生物活性小分子化合物的集合,是相关疾病药物筛选的有效工具; | |||
L9100 | 磷酸酶抑制剂化合物库 | 79 compounds | |
79 种已知活性的磷酸酶抑制剂的集合,可用于化合物筛选、化学基因组学、药理分析等方面; | |||
L1520 | 膜蛋白靶向化合物库 | 4175 compounds | |
L2510 | 脂代谢化合物库 | 492 compounds | |
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选; | |||
L1120 | AMPK靶向分子库 | 80 compounds | |
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选; | |||
L1110 | 微管靶向化合物库 | 142 compounds | |
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选; | |||
L1310 | 细胞骨架化合物库 | 759 compounds | |
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选; | |||
L2195 | 抗前列腺癌化合物库 | 2070 compounds | |
2070 种与前列腺癌相关的化合物,可以用于高通量和高内涵筛选 | |||
L5300 | 线粒体靶向库 | 812 compounds | |
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究; | |||
L2500 | 人内源代谢化合物库 | 499 compounds | |
499 种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选; | |||
L2540 | 肠道微生物代谢化合物库 | 614 compounds | |
614 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选; | |||
L1380 | 转录因子库 | 695 compounds | |
695 种转录因子靶向、结构新颖的化合物; | |||
L3300 | 组胺&褪黑色素化合物库 | 153 compounds | |
153 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L9500 | 表型筛选靶点鉴定库 | 1796 compounds | |
1796 种靶点明确的已知活性化合物,适合表型筛选; | |||
L2560 | 代谢化合物库 | 2320 compounds | |
2320 种代谢途径相关的化合物,可用于高通量和高内涵筛选。 | |||
L2152 | 靶向治疗药物库 | 119 compounds | |
119 个肿瘤靶向治疗药物,可以用于高通量和高内涵筛选; | |||
L2520 | 糖代谢化合物库 | 702 compounds | |
702 种糖代谢相关的化合物,可用于高通量和高内涵筛选; | |||
L2530 | 小鼠代谢化合物库 | 218 compounds | |
218 种小鼠代谢化合物的集合,可用于高通量筛选和高内涵筛选; | |||
L2800 | 5-羟色胺分子库 | 268 compounds | |
268 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L5800 | 药物代谢杂质库 | 197 compounds | |
197 种药物异构体/代谢产物的特有集合,可用于高通量、高内涵筛选; | |||
L9820 | β-内酰胺类化合物库 | 97 compounds | |
97 种β-内酰胺类化合物的集合,可以用于高通量和高内涵筛选; | |||
L6210 | 藏药化合物库 | 747 compounds | |
747 种藏药来源的天然产物分子集合,可以用于高通量和高内涵筛选; | |||
L2570 | 人代谢物化合物库 | 4454 compounds | |
4454 种人代谢物的独特集合,用于高通量、高内涵筛选; | |||
L6020 | 天然产物单体化合物库 | 16627 compounds | |
16627 种精选天然产物集合,结构多样,遍布多种动植物与微生物; | |||
L2501 | 人内源代谢化合物库 Plus | 1283 compounds | |
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8585 |
TA-03
7-Methoxytacrine,7-Meota |
AChE | Neuroscience |
TA-03 (7-Meota) 是一种有效的 AChE 抑制剂,可治疗 AD 的认知表现。 | |||
T4645 |
TA-01
|
p38 MAPK; Casein Kinase; Autophagy | Autophagy; MAPK; Metabolism; Stem Cells |
TA01 是一种心源性抑制剂,有效抑制CK1和p38 MAPK,其对 CK1ε,CK1δ 和 p38 MAPK 的IC50值分别为 6.4 nM,6.8 nM 和 6.7 nM。 | |||
T4646 |
TA-02
|
p38 MAPK; Autophagy | Autophagy; MAPK |
TA02 是一种Adezmapimod 类似物,是p38 MAPK 的抑制剂,其IC50值为 20 nM。它和Adezmapimod、SB 202190 具有相似的心源活性,可抑制 TGFBR-2。 | |||
T13072 |
Taltirelin acetate
TA-0910 acetate |
Thyroid hormone receptor(THR) | Endocrinology/Hormones |
Taltirelin acetate (TA-0910 acetate) 是促甲状腺激素释放激素受体(TRH-R)超激动剂(IC50:910 nM),能够刺激细胞溶质Ca2+浓度增加 (Ca2+释放) ,其EC50值为 36 nM。 | |||
T2587 |
Ecabet Sodium
TA-2711E,TA-2711,伊卡倍特钠 |
Reactive Oxygen Species; Antibacterial | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Ecabet Sodium (TA-2711) 可通过抑制活性氧的产生,促进幽门螺杆菌的根除,可用于胃肠道疾病的相关研究。 | |||
T34767 |
TA-1887
TA 1887,TA1887 |
||
TA-1887 is a new type of selective inhibitor of sglt2 for the treatment of type 2 diabetes. It has a significant hypoglycemic effect in KK (HF-KK) mice fed a high-fat diet. TA-1887 has good pharmacokinetic characteristics and significantly increases UGE | |||
T1782L |
Canagliflozin hemihydrate
JNJ28431754,TA 7284,TA7284,TA-7284,JNJ 28431754,JNJ-28431754 |
SGLT | GPCR/G Protein |
Canagliflozin hemihydrate (TA 7284) (JNJ28431754 hemihydrate) 是一种选择性的 SGLT2 抑制剂,作用于表达 mSGLT2,rSGLT2 和 hSGLT2 的 CHO 细胞,IC50 分别为 2 nM,3.7 nM 和 4.4 nM。 | |||
T28908 |
TA-606
TA-606 free,TA606 |
||
TA-606 is an angiotensin type 1 receptor antagonist with antihypertensive activity. | |||
T28909 |
TA-993 maleate
TA 993,TA993,TA-993 |
||
TA-993 is a calcium channel antagonist. TA-993 has an antithrombotic effect. | |||
T13909 | TA-1801 | Others | Others |
TA-1801 is an agent of hypolipidemic. | |||
T13910 |
TA-7552
|
Others | Others |
TA-7552 is a potent agent of cholesterol-lowering. | |||
T6542 |
Imidapril hydrochloride
Novaloc,Imidapril HCl,盐酸咪达普利,Tanapril,TA-6366 |
RAAS | Endocrinology/Hormones |
Imidapril hydrochloride (Tanapril) 是一种血管紧张素转换酶 (ACE) 抑制剂,具有抗高血压活性。 | |||
T28225 |
Obicetrapib
TA8995,AMG899,Obicetrapib (free base),AMG 899,AMG-899,Obicetrapib,TA-8995 |
CETP | Metabolism |
Obicetrapib (AMG-899) 是胆固醇酯转移蛋白的抑制剂。 | |||
T1782 |
Canagliflozin
卡格列净,JNJ 24831754ZAE,JNJ 28431754AAA,TA 7284,JNJ 28431754 |
SGLT | GPCR/G Protein |
Canagliflozin (JNJ 28431754AAA) 是SGLT2的选择性抑制剂,在表达 mSGLT2,rSGLT2 和 hSGLT2 的 CHO 细胞上,IC50分别为 2 nM,3.7 nM 和 4.4 nM。 | |||
T28907 |
TA-270
LS-123351,LS123351 |
||
TA-720, a 5-lipoxygenase inhibitor, is used potentially for the treatment of asthma. | |||
T13769 |
TA-316
Megakaryocytes/platelets inducing agent |
Others | Others |
Megakaryocytes/platelets inducing agent being useful in treating diseases involving thrombopenia. Megakaryocytes/platelets inducing agent is an inducing agent for megakaryocytes and/or platelets from pluripotent stem cells. | |||
T16972 | TA 0910 acid-type | Others | Others |
TA 0910 acid-type is a metabolite of TA 0910. TA-0910 is a metabolically stable analog of thyrotropin-releasing hormone. | |||
T24849 |
TachypleginA-2
tA 2,tA-2,tA2 |
||
TachypleginA-2 is a parasite motility and invasion inhibitor. | |||
T32305 |
JNJ-39933673
JNJ-39933673 hemihydrate,TA 1887,TA-1887 |
||
JNJ-39933673 is a bio-active chemical. | |||
T34762 |
T-0201
T 0201,TA0201,TA-0201,TA 0201 |
||
T-0201 (TA 0201) is a highly potent, long-acting, orally active, and selective ETA receptor antagonist. T-0201 also inhibited ET-1-induced pulmonary artery contraction in isolated rabbits. | |||
T25027 |
Albocycline
TA-2407,Ingramycin |
||
Albocycline is a Macrolide antibiotic from Streptomyces bruneogriseus nov. sp. MCRL-0129; specifically anti-staphylococcal, including antibiotic-resistant strains. | |||
T2334 |
Avanafil
阿伐那非,TA1790 |
PDE | Metabolism |
Avanafil (TA1790) 是一种高活性PDE-5抑制剂,IC50=5.2 nM,对PDE1,PDE6和PDE11活性较低。 | |||
T6885 |
Marimastat
BB2516,马立马司他,KB-R8898,TA2516 |
MMP | Proteases/Proteasome |
Marimastat (BB2516) 是一种血管生成和转移抑制剂,限制血管的生长和生成。它是一种广谱的,具有口服活性的MMPs 抑制剂,有效抑制 MMP-9 , MMP-1, MMP-2, MMP-14, MMP-7,用于癌症的研究。 | |||
T7590 |
Taltirelin
TA-0910,他替瑞林 |
Thyroid hormone receptor(THR) | Endocrinology/Hormones |
Taltirelin (TA-0910) 是促甲状腺激素释放激素受体(TRH-R)超激动剂(IC50:910 nM),能够刺激细胞溶质 Ca2+浓度增加 (Ca2+释放) (EC50:36 nM)。 | |||
T19794 |
Temafloxacin
替马沙星,Omniflox |
Antibiotic | Microbiology/Virology |
Temafloxacin (Omniflox) 是一种喹诺酮类广谱抗菌剂,对革兰氏阳性菌、革兰氏阴性菌和厌氧菌均有效。 | |||
T68220 |
Clentiazem maleate
|
||
Clentiazem maleate is a calcium channel antagonist . | |||
T124207 |
AAL Toxin TA1
|
||
AAL Toxin TA1 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124207。 | |||
T124208 |
AAL Toxin TA2
|
||
AAL Toxin TA2 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124208。 | |||
T38344 |
Lalistat 1
ZINC795230 |
Antibacterial | Microbiology/Virology |
Lalistat 1是溶酶体酸性脂肪酶(LAL)抑制剂(IC50 = 68 nM)和流感病毒IgA1蛋白酶的抑制剂。Lalistat 1可用于有关尼曼-皮克C 型疾病的研究。 | |||
T3283 |
Cetilistat
新利司他,ATL-962 |
Lipid | Metabolism |
Cetilistat (ATL-962) 是胰腺脂肪酶 (pancreatic lipase) 抑制剂,能够抑制大鼠脂肪酶(IC50:54.8 nM)和人胰脂肪酶(IC50:5.95 nM)的活性,可用作有效的抗肥胖药。 | |||
T6897 |
Monomethyl auristatin E
一甲基澳瑞他汀E,Vedotin,MMAE |
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Monomethyl auristatin E (MMAE) 是海兔毒素 10 的合成衍生物,是一种抗有丝分裂剂,通过阻断微管蛋白的聚合来抑制细胞分裂,并且还具有抑制抗体-药物偶联物的活性。 | |||
T12632L |
(S)-Mirtazapine
(S)-6-Azamianserin,(S)-Org3770 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
(S)-Mirtazapine ((S)-Org3770) 是 Mirtazapine 的 S(+)-对映体。(S)-Mirtazapine 是一种选择性 5-HT2 受体拮抗剂,具有促痛觉作用,常与Mirtazapine 的 R(-)-对映体混合使用来研究抑郁症。 | |||
T1425 |
Pemirolast potassium
BMY 26517,TWT-8152,吡嘧司特钾 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Pemirolast potassium (TWT-8152) 是 H1组胺受体拮抗剂和肥大细胞稳定剂,是一种具有抗过敏特性的嘧啶酮衍生物。 | |||
T7057 |
Methylstat
|
Histone Demethylase; Others | Chromatin/Epigenetic; Others |
Methylstat 是一种含有 Jumonji C 结构域的组蛋白去甲基化酶 (JMJD) 抑制剂的甲酯前药,具有良好的细胞渗透性。在体外试验中,methylstat 的游离酸可抑制 JMJD2A、JMJD2C、JMJD2E、PHF8 和 JMJD3,IC50 值分别约为 4.3、3.4、5.9、10 和 43 µM。 Methylstat 抑制 JMJD2C 敏感的食管癌细胞系 KYSE150 的生长,GI50 为 5.1 µM,而 methylstat 的游离酸在高达 100 µM 时不抑制细胞生长。 Methylstat 以浓度依赖性方式在多个位点诱导组蛋白高甲基化(KYSE150 细胞中 H3K4me3 和 H3K9me3 的 EC50 = 10.3 和 8.6 µM,MCF-7 细胞中的 EC50 分别为 6.7 和 6.3 µM)。 | |||
T8748 |
Exendin-4 acetate
|
Glucagon Receptor | GPCR/G Protein |
Exendin-4 acetate 是一种长效的 glucagon-likepeptide-1 受体激动剂(IC50:3.22 nM),是一种由39个氨基酸组成的多肽。。 | |||
T10056 |
Neurokinin antagonist 1
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Neurokinin antagonist 1是一种有效的是神经肽拮抗剂,可用于研究神经系统疾病。 | |||
T17842 |
DOTA-NHS-ester
|
Others | Others |
DOTA-NHS-ester 是 affibody 分子的接头,应用于小动物 PET、SPECT 和 CT。 它可用于标记放射治疗剂或成像探针以检测肿瘤。 | |||
TP1060 |
GPRP acetate (67869-62-9 free base)
Pefabloc FG,Pefa 6003,GPRP acetate |
Others | Others |
GPRP acetate (Pefabloc FG) 是纤维蛋白聚合抑制剂,可抑制纤维蛋白原与血小板膜糖蛋白 Ⅱb/IIIa 复合物(糖蛋白 IIb/IIIa 受体)之间的相互作用。 | |||
T77749 |
Upifitamab
|
Others | Others |
Upifitamab 是 upifitamab rilsodotin 的裸抗,可用于合成抗体偶联活性分子 UPRI,可用用于研究癌症。 | |||
TP2337 |
Ganirelix Acetate
|
GNRH Receptor | GPCR/G Protein |
Ganirelix Acetate 是一种促性腺激素释放激素 (GnRH) 受体拮抗剂。 | |||
T78108 |
µ-Conotoxin-CnIIIC acetate
|
Sodium Channel | Membrane transporter/Ion channel |
µ-Conotoxin-CnIIIC acetate 是一种高效的 NaV1.4 钠通道拮抗剂,是由22个氨基酸组成的芋螺肽,可用于肌肉松弛和缓解疼痛。 | |||
T16756 |
Risarestat
CT 112 |
Reductase | Endocrinology/Hormones; Metabolism |
Risarestat (CT-112)是一种有效的醛糖还原酶抑制剂和甲状腺激素受体 (TR) 拮抗剂,可用于治疗低血糖症。 | |||
T50031 |
Virstatin
|
Others | Others |
Virstatin 是一种新型抗病毒药物,是一种有效的病毒复制抑制剂,已被证明对多种病毒有效,包括单纯疱疹病毒(HSV)、人类免疫缺陷病毒(HIV)和流感病毒等。 | |||
T37637 |
4,4-Dimethoxy-2-butanone
|
Endogenous Metabolite | Metabolism |
4,4-Dimethoxy-2-butanone 对大鼠实验中显示出亚急性口服毒性。 | |||
T13074 |
TAM-IN-2
|
TAM Receptor | Tyrosine Kinase/Adaptors |
TAM-IN-2 是一种 TAM 抑制剂,吡咯并三嗪化合物 0904。 | |||
T22328 |
Ethyl potassium malonate
Potassium 3-ethoxy-3-oxopropanoate,Malonic Acid Monoethyl Ester Potassium Salt,丙二酸单乙酯钾盐 |
Others | Others |
Ethyl potassium malonate 是琥珀酸脱氢酶的竞争性抑制剂,可作为生产丙二酸(三甲基甲硅烷基)乙酯的前体,丙二酸乙酯用于通过酰化制备 β-酮酯,并作为制备丙二酸叔丁酯的中间体。 | |||
T28226 |
Octahydroaminoacridine succinate
|
Others | Others |
Octahydroaminoacridine succinate 是一种乙酰胆碱酯酶抑制剂,可用于治疗阿尔茨海默病。 | |||
T14342 |
Atorvastatin lactone
|
HMG-CoA Reductase | Metabolism |
Atorvastatin lactone 是一种 Atorvastatin 的前药。其中 Atorvastatin 是口服具有活力的 3- 羟基 -3- 甲基戊二酰辅酶 A 还原酶抑制剂。 | |||
T13219 |
TTA-Q6
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
TTA-Q6 是一种选择性 T 型 Ca2+ 通道拮抗剂,具有潜在的抗肿瘤和免疫调节活性,可抑制肿瘤细胞摄取细胞外钙离子,诱导细胞内钙缺乏和内质网(ER)应激,用于治疗神经系统疾病。 | |||
T65232 |
HEDTA
N-(2-Hydroxyethyl)ethylenediaminetriacetic acid |
Others | Others |
HEDTA 是一种螯合剂,常与柠檬酸联合用药来研究血液疾病和脑部血液应激。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T65128 |
Tartaric acid disodium dihydrate
Disodium L-(+)-Tartrate Dihydrate |
Phosphatase; Endogenous Metabolite | Metabolism |
Tartaric acid disodium dihydrate (Disodium L-(+)-Tartrate Dihydrate) 常用来制作分子生物学和细胞培养中的缓冲液,。Tartaric acid disodium dihydrate 是酸性磷酸酶抑制剂, 可增加秋水仙碱结合 tubulin1的概率。 | |||
T21665 |
DL-α-Hydroxyglutaric acid disodium salt
disodium 2-hydroxypentanedioate,DL-Α-羟基戊二酸二钠 |
Others | Others |
DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) 是一种 α-羟基酸,由 (R) -5-oxy-2-tetrahydrofuran 羧酸水解形成,在人类神经代谢疾病 D-α-羟基戊二酸尿症中过量产生。 | |||
T4727 |
Taurolithocholic acid sodium salt
牛磺石胆酸钠,Sodium taurolithocholate |
Others; Calcium Channel | Membrane transporter/Ion channel; Metabolism; Others |
Taurolithocholic acid sodium salt (Sodium taurolithocholate) 是抑胆剂和 Ca2+激动剂,可抑制放射性配体与毒蕈碱 M1 结合。 | |||
TP1180 |
Dolastatin 10
尾海兔素10,NSC 376128,DLS 10 |
Microtubule Associated | Cytoskeletal Signaling |
Dolastatin 10 (DLS 10) 是一种多肽,可以抑制微管蛋白聚合,显示除抗有丝分裂的活性。 | |||
TQ0024 |
3-Hydroxyglutaric acid
|
Endogenous Metabolite | Metabolism |
3-Hydroxyglutaric acid 是一种戊二酸的衍生物。 | |||
T8155 |
Maltoheptaose
|
Phospholipase | Metabolism |
Maltoheptaose 是一种含有七个葡萄糖单元的麦芽低聚糖。它是一种磷酸化酶 B (phosphorylase B) 的活化剂,可用于 2-磷酸庚糖的制备。 | |||
T75319 |
Taurodeoxycholic acid
Taurodeoxychloic acid |
Apoptosis; Calcium Channel; Caspase | Apoptosis; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome |
Taurodeoxycholic acid (Taurodeoxychloic acid) 是脱氧胆酸的胆汁酸牛磺酸共轭物,是一种人体代谢物,可稳定线粒体膜,减少自由基形成。Taurodeoxycholic acid 通过阻断钙介导的凋亡通路以及 Caspase-12 激活来抑制凋亡 (apoptosis)。Taurodeoxycholic acid具有神经保护活性,可用于研究 3-硝基丙酸诱导或稳定遗传的亨廷顿舞蹈病 (HD) 。 | |||
T3603 |
Sodium lauryl sulfoacetate
月桂醇磺基乙酸酯钠,鱼腥草,新鱼腥草素钠,Sodium houttuyfonate |
NF-κB; MAPK | MAPK; NF-κB |
Sodium lauryl sulfoacetate (Sodium houttuyfonate) 是一种植物来源的固体阴离子表面活性剂,也是一种具有抗免疫抑制作用的免疫佐剂。 | |||
T10935 |
D-Glutamic acid
(R)-Glutamic acid,D-谷氨酸 |
Endogenous Metabolite | Metabolism |
D-Glutamic acid ((R)-Glutamic acid) 是一种广泛用于药物和食品中的L-glutamic acid 对映异构体。 | |||
TJS1382 |
Taraxerone
蒲公英赛酮 |
Dehydrogenase | Metabolism |
Taraxerone 是分离自景天的天然产物。它可以增强乙醇脱氢酶和乙醛脱氢酶活性,EC50分别为 512.42 μM 和 500.16 μM。 | |||
T5781 |
taraxasteryl acetate
蒲公英甾醇醋酸酯,醋酸蒲公英酯 |
Antibacterial | Microbiology/Virology |
Taraxasteryl acetate 是分离自矢状疟原虫中,具有广谱的抗炎活性。它能够改善右旋糖酐、酵母聚糖及花生四烯酸诱导的大鼠后爪水肿。它可用于研究局部炎症。 | |||
T6534 |
Histamine dihydrochloride
组胺二盐酸盐,peremin,Ceplene,Histamine 2HCl |
Endogenous Metabolite; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience |
Histamine dihydrochloride (Ceplene) 是 Histamine 的二盐酸形式。Histamine 是一种有机氮化合物,是一种强效的胃分泌兴奋剂,支气管平滑肌收缩剂,血管舒张剂,也是一种中枢作用的神经递质。 | |||
TN1438 |
beta-Amyrin acetate
beta-香树脂醇乙酸酯 |
Antioxidant; HMG-CoA Reductase; Epoxide Hydrolase; Antifungal | Metabolism; Microbiology/Virology; oxidation-reduction |
beta-Amyrin acetate 抑制 HMG-CoA 还原酶 (HMGCR) 和 sEH 活性,IC50 为 3.4 μM。 beta-Amyrin acetate 具有抗炎、抗真菌、抗氧化和抗高血脂活性。 | |||
T4927 |
4-Guanidinobutanoic acid
4-GBA,4-胍基丁酸,4-Guanidinobutyric acid |
Endogenous Metabolite | Metabolism |
4-Guanidinobutanoic acid (4-GBA) 是一种 L-精氨酸代谢物,已用于肠道转运研究。 它已专门用于人质子偶联氨基酸转运蛋白 hPAT1。 | |||
T8092 |
Taurohyodeoxycholic acid sodium salt
Sodium taurohyodeoxycholate hydrate |
Caspase | Apoptosis; Proteases/Proteasome |
Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) 通过阻断钙介导的细胞凋亡途径以及 Caspase-12 活化来防止细胞凋亡 | |||
TN1039 |
Tamarixetin
柽柳黄素,4'-O-Methyl Quercetin |
Endogenous Metabolite; Immunology/Inflammation related | Immunology/Inflammation; Metabolism |
Tamarixetin (4'-O-Methyl Quercetin) 是一种槲皮素的天然类黄酮衍生物,具有抗氧化、抗炎作用,能够防止心肌肥厚。 | |||
T11811 |
Laetanine
|
Parasite | Microbiology/Virology |
Laetanine 是从Litsea laeta 提取到的一种去甲马飞生物碱,有抗疟原虫活性。 | |||
T2972 |
Rutaecarpine
Rutacarpine,吴茱萸次碱,Rhetine,Rutecarpine |
COX | Immunology/Inflammation; Neuroscience |
Rutaecarpine (Rhetine) 是从槐木中提取的一种生物碱,是 COX-2的抑制剂,IC50值为0.28 μM。 | |||
T5082 |
Calcium 2-hydroxy-4-(methylthio)butanoate
羟基蛋氨酸钙,calcium hydroxymethionine,2-Hydroxy-4-(methylthio)butyric acid calcium salt |
Others; Endogenous Metabolite | Metabolism; Others |
Calcium 2-hydroxy-4-(methylthio)butanoate (Calcium 2-hydroxy-4-(calcium hydroxymethionine)) 是内源性代谢产物的一种。 | |||
T2S0690 |
Ecliptasaponin A
早莲苷 A,旱莲苷A,Echinocystic acid-3-o-glucoside |
Others | Others |
Ecliptasaponin A (Echinocystic acid-3-o-glucoside) 是一种墨旱莲 (Eclipta prostrate) 中分离得到的五环三萜皂苷。其中墨旱莲是一种具有多效作用的滋补草药,如抗炎、保肝、抗氧化和免疫调节。 | |||
T5704 |
Entadamide-A-β-D-glucopyranoside
(E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-,榼藤子酰胺A-Β-D-吡喃葡萄糖苷,榼藤子酰胺A-β-D-吡喃葡萄糖 |
Others | Others |
Entadamide-A-β-D-glucopyranoside ((E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-) 是一种菜豆虫种子的主要成分,具有抗补体作用。 | |||
TN3500 |
beta-Amyrone
β-Amyron,β-香树脂酮 |
COX; AChR; PPAR; Antifection | DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
beta-Amyrone (β-Amyron) 对基孔肯雅病毒复制具有抗真菌活性,EC50 为 86 uM。 beta-Amyrone 通过抑制 COX-2 的表达而具有抗炎活性。 beta-Amyrone 表现出抗α-葡萄糖苷酶抑制活性和中等 AChE 活性。 β-Amyrone 可用于炎症、感染和肥胖等疾病的研究。 | |||
T1373 |
AC-Beta-ALA-OH
|
Amino Acids and Derivatives | Metabolism |
AC-Beta-ALA-OH 是单 N-保护氨基酸 (MPAA) 配体,也是异常氨基酸代谢物。 | |||
T4S1469 |
Cucurbitacin IIb
葫芦素IIB,雪胆素乙 |
Apoptosis; Others | Apoptosis; Others |
Cucurbitacin IIb 是一种雪胆中的活性成分。它阻碍 STAT3,JNK 和 Erk1/2 的磷酸化,提高 IκB 和 NF-κB (p65) 的磷酸化水平,抑制 NF-κB (p65) 的核转位,降低 IκBα 和 TNF-α 的 mRNA 水平。它能够诱导细胞凋亡,具有抗炎作用。 | |||
TC0027 |
beta-Sitosterol acetate
|
Others | Others |
beta-Sitosterol acetate 是几种被称为植物甾醇的植物性物质之一。 | |||
TN5443 |
Kaempferol 3,4',7-triacetate
Kaempferol 3,4,7-triacetate,3,7-Bis(acetyloxy)-2-[4-(acetyloxy)phenyl]-5-hydroxy-4H-1-benzopyran-4-one,3,7,4'-Tri-O-acetylkaempferol,[4-(3,7-diacetyloxy-5-hydroxy-4-oxochromen-2-yl)phenyl] acetate |
Others | Others |
Kaempferol 3,4',7-triacetate (3,7,4'-Tri-O-acetylkaempferol) 是椴木草本植物的天然产物。 | |||
TC0019 |
Pregnenolone acetate
孕烯醇酮醋酸酯,3β-Hydroxy-5-pregnen-20-one acetate |
Cannabinoid Receptor; Endogenous Metabolite | GPCR/G Protein; Metabolism |
Pregnenolone acetate 是一种强大的神经类固醇,是各种类固醇激素(包括类固醇酮)的主要前体。它作为大麻素 CB1 受体的信号特异性抑制剂,抑制由 CB1 受体介导的四氢大麻酚 (THC) 的作用。它可以保护大脑免受大麻中毒。 | |||
T3S1692 |
Octahydrocurcumin
|
Anti-infection; NF-κB; Reactive Oxygen Species; ROS | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Octahydrocurcumin 是一种姜黄素的氢化衍生物,是姜黄素的代谢物。 | |||
TN7071 |
Ergosterol Acetate
Ergosta-5,7,22-trien-3-beta-yl acetate |
Others | Others |
Ergosterol Acetate (Ergosta-5,7,22-trien-3-beta-yl acetate) 是来自红曲霉的 Ergosterol 的乙酸酯衍生物之一。 | |||
T1243 |
Hydrocortisone acetate
Cortisol 21-acetate,Hydrocortisone 21-acetate,醋酸氢化可的松 |
Glucocorticoid Receptor; Annexin A; Endogenous Metabolite | Endocrinology/Hormones; GPCR/G Protein; Metabolism |
Hydrocortisone acetate (Cortisol 21-acetate) 是皮质类固醇,能够减少轻微皮肤刺激或痔疮引起的肿胀、搔痒和疼痛。 | |||
T3S1873 |
Talatisamine
塔拉乌头胺,塔拉萨敏 |
Potassium Channel | Membrane transporter/Ion channel |
Talatisamine 是一种乌头生物碱,对K+通道有特异性阻滞作用。它能减弱 beta- 淀粉样低聚物对培养的皮层神经元的毒性。 | |||
T0186 |
Docetaxel trihydrate
RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate,多西他赛三水合物 |
Apoptosis; BCL; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Docetaxel trihydrate (RP-56976 Trihydrate) 是一种抗肿瘤试剂,抑制微管解聚的IC50值为 0.2 μM。它是紫杉醇的半合成类似物,能减弱 bcl-2 和 bcl-xL 基因表达的影响。它阻滞G2/M 细胞周期,导致细胞凋亡。 | |||
T11589 |
Hydroxycitric acid tripotassium hydrate
柠檬酸钾一水合物,三水合钾柠檬酸,Potassium citrate monohydrate |
ATP Citrate Lyase; HIF/HIF Prolyl-Hydroxylase; HIF | Angiogenesis; Chromatin/Epigenetic; Metabolism |
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) 是一种藤黄果的主要活性成分,也是一种柠檬酸的衍生物。它可竞争性抑制柠檬酸裂解酶 (ATP citrate lyase) ,并具有减肥作用。它有效抑制结石形成,并抑制HIF,具有抗氧化,抗炎和抗肿瘤活性。 | |||
T5248 |
(R)-3-Hydroxybutanoic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
(R)-3-Hydroxybutanoic acid 是一种代谢物,在 3-羟基丁酸脱氢酶催化下由乙酸乙酯转化而成。它可以作为营养来源和抗生素、维生素和信息素的前体。 | |||
T6212 |
Combretastatin A4
CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09 |
Microtubule Associated | Cytoskeletal Signaling |
Combretastatin A4 (CA4) 是一种微管靶向剂,可结合 β-tubulin,Kd 值为 0.4 μM。 | |||
TCP2830 |
Neryl acetate
Nerol acetate,Acetic acid neryl ester,(Z)-3,7-二甲基-2,6-辛二烯-1-醇乙酸酯,cis-Geranyl acetate |
Others | Others |
Neryl acetate (Acetic acid neryl ester) 是一种分离自柑桔油中的物质。 | |||
TQ0196 |
Cucurbitacin I
NSC-521777,JSI-124,Elatericin B,葫芦素 I |
JAK; STAT | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Cucurbitacin I (JSI-124) 是从曲莲中提取的一种天然产物,是 JAK2/STAT3选择性抑制剂,有抗肿瘤活性。 | |||
T7068 |
Eicosapentaenoic acid ethyl ester
Icosapent ethyl,顺-二十碳五烯酸乙酯,EPA ethyl ester,Ethyl eicosapentaenoate |
Others; Endogenous Metabolite | Metabolism; Others |
Eicosapentaenoic acid ethyl ester (Ethyl eicosapentaenoate) 是 一种ω-3 脂肪酸剂和人内源性代谢物。 | |||
T19493 |
Octadecanal
十八烷醛,stearaldehyde |
Endogenous Metabolite | Metabolism |
Octadecanal (stearaldehyde) 是存在于大腿和胸部肌肉中的一种长链醛。 | |||
T2977 |
Vanillin acetate
Acetovanillin,乙酰香兰酯,Acetylvanillin,4-Formyl-2-methoxyphenyl acetate,乙酰香兰素,4-Acetoxy-3-methoxybenzaldehyde |
Others | Others |
Acetylvanillin 可由香草醛用乙酸酐处理后得到。 | |||
T1126 |
Penicillin V Potassium
青霉素V钾,Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt |
Antibacterial; Antibiotic | Microbiology/Virology |
Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) 是一种有口服活性的抗生素。它可抑制链球菌,艰难梭菌和金黄色葡萄球菌的生长,可研究中耳炎,鼻窦炎,咽炎和扁桃体炎。 | |||
T5071 |
4-Methyl-2-oxopentanoic acid
4-甲基-2-氧代戊酸,4-Methyl-2-oxovaleric acid |
Others; Endogenous Metabolite | Metabolism; Others |
4-Methyl-2-oxopentanoic acid (4-Methyl-2-oxovaleric acid) 是一种非正常代谢物,是一种神经毒素和代谢毒素。 | |||
T2S0157 |
Methyl palmitate
Methyl hexadecanoate,软脂酸甲酯,十六烷酸甲酯,Palmitic acid methyl ester,十六酸甲酯 |
Others | Others |
Methyl palmitate (Palmitic acid methyl ester) 是存在于绿色核桃壳中的杀螨化合物,具有抗炎和抗纤维化作用,可抑制吞噬活性和免疫应答。 | |||
T8008 |
2-Methylheptanoic Acid
|
Others | Others |
2-Methylheptanoic acid 是一种调味剂,分离自蜂蜜中。 | |||
T3S2390 |
Caftaric acid
trans-Caftaric acid,单咖啡酰洒石酸 |
Others | Others |
Caftaric acid (trans-Caftaric acid) 是一种具有抗氧化和抗炎作用的天然产物,具有抗致突变性,也是Src 家族激酶介导的蛋白质-蛋白质相互作用的抑制剂。 | |||
T7930 |
Linalyl Acetate
|
Others | Others |
Linalyl acetate 是多种植物精油的主要成分,具有潜在的抗炎活性。 | |||
T73772 |
Estrone sulfate potassium
|
Endogenous Metabolite | Metabolism |
Estrone sulfate potassium 是一种雌激素酯和共轭物,是一种天然内源性类固醇。 | |||
TN6901 |
Methyl myristate
肉豆蔻酸甲酯,methyl tetradecanoate |
Others | Others |
Methyl myristate (methyl tetradecanoate) 是一种肉豆蔻酸经酯化反应得到的饱和脂肪酸甲酯。对 B16F10 黑色素瘤具有显著的诱导作用。 | |||
T0683 |
Mevastatin
Compactin,ML236B,美伐他汀 |
Apoptosis; Antibacterial; Antibiotic; HMG-CoA Reductase; Autophagy; Lipid | Apoptosis; Autophagy; Metabolism; Microbiology/Virology |
Mevastatin (ML236B) 是他汀类 HMG-CoA 还原酶抑制剂。它是一种降脂药,可诱导细胞凋亡,将癌细胞阻滞在 G0/G1期。它还可增加内皮型一氧化氮合酶的 mRNA 和蛋白质水平。它有抗肿瘤活性,用于心血管疾病的研究。 | |||
TN1342 |
8-Epidiosbulbin E acetate
8-表黄药子素E乙酸酯 |
Anti-infection; Antibacterial | Microbiology/Virology |
8-Epidiosbulbin E acetate 是从 Dioscorea bulbifera L.中发现的呋喃类化合物,对耐多药细菌具有广谱的质粒治疗活性。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01580 |
PRSS2 Protein, Mouse, Recombinant (His)
Tesp4,protease, serine 2,Try2,Ta,TRY8,TRYP,Prss2 |
Mouse | HEK293 Cells |
Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247). PRSS2 contains one peptidase S1 domain. It is secreted into the duodenum, hydrolysing peptides into their smaller building blocks, which is necessary ... | |||
TMPY-02869 |
MMP-12 Protein, Human, Recombinant (catalytic domain)
HME,ME,MMP-12,MME,matrix metallopeptidase 12 |
Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ... | |||
TMPY-03425 |
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ... |
Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... | |||
TMPY-00570 |
Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
ALPI,PALP,PLAP,PLAP-1,alkaline phosphatase, placen<... |
Human | P. pastoris (Yeast) |
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. | |||
TMPY-04925 |
CD8 beta Protein, Human, Recombinant, Biotinylated
LY3,LYT3,CD8b molecule,P37,LEU2,CD8 β,CD8B1 |
Human | HEK293 Cells |
CD8 beta Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1. | |||
TMPY-00539 |
GSTA1 Protein, Human, Recombinant (His)
glutathione S-transferase alpha 1,GTH1,GST2,glu... |
Human | HEK293 Cells |
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adeno... | |||
TMPY-02227 |
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)
白细胞介素,interleukin 1, beta,白介素,interleukin 1, β,IL-1... |
Rat | E. coli |
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is Q63264-1. | |||
TMPY-03945 |
Latent TGF beta 1 Protein, Rat, Recombinant (His)
TGF β1,transforming growth factor, β1,transforming growth fa... |
Rat | HEK293 Cells |
Latent TGF beta 1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P17246. | |||
TMPY-02445 |
IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant
interleukin 1, beta,IL-1 β,白介素,interleukin 1, β,白细胞... |
Rhesus | E. coli |
IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P48090. | |||
TMPY-00767 |
Cystatin C Protein, Human, Recombinant (His)
ARMD11,cystatin C |
Human | HEK293 Cells |
Cystatin C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is A0A0K0K1J1. | |||
TMPY-03467 |
IFN-beta Protein, Mouse, Recombinant
Ifb,IFN-β,interferon, beta 1, fibroblast,干扰素,IFNB,I... |
Mouse | HEK293 Cells |
IFN-beta Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.3 kDa and the accession number is P01575. | |||
TMPY-00006 |
GRO beta/CXCL2 Protein, Human, Recombinant
GROb,MIP-2a,CINC-2a,GRO β/CXCL2,MIP2,MGSA-b,GRO2,MIP2A,SCYB2... |
Human | E. coli |
GRO beta/CXCL2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is A0A024RDD9. | |||
TMPY-02159 |
Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His)
Integrin alpha 5 β1,Integrin α5 β 1,integrin, α5 (fibronecti... |
Human | HEK293 Cells |
Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 192 kDa and the accession number is P08648&P05556-1. | |||
TMPY-01686 |
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His)
β-2 microglobulin,beta-2 microglobulin |
Human | HEK293 Cells |
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P61769. | |||
TMPY-04643 |
Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)
integrin, α5 (fibronectin receptor, α polypeptide),integrin,... |
Mouse | HEK293 Cells |
Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is NP_032428.2&NP_067334.1. | |||
TMPY-01049 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant
IL-1 beta,interleukin 1, beta,IL-1B,interl... |
Human | E. coli |
IL-1 beta/IL-1F2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 kDa and the accession number is P01584. | |||
TMPJ-01468 |
pro-Beta NGF Protein, Human, Recombinant
β-NGF,NGF,NGFB,Beta-NGF,Beta-Nerve Growth ... |
Human | E. coli |
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration. | |||
TMPY-02568 |
IL-1 beta/IL-1F2 Protein, Canine, Recombinant
interleukin 1, beta,IL-1 β,interleukin 1, β |
Canine | E. coli |
IL-1 beta/IL-1F2 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.6 kDa and the accession number is Q28292. | |||
TMPY-00720 |
Contactin 1 Protein, Human, Recombinant (His)
contactin 1,F3,GP135,MYPCN |
Human | HEK293 Cells |
Contactin 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 110 kDa and the accession number is A0A024R104. | |||
TMPY-04211 |
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
transforming growth factor, β1,TGF β1,transforming growth fa... |
Cynomolgus | HEK293 Cells |
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa. | |||
TMPJ-01467 |
Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)
Oncostatin-M,OSM |
Human | E. coli |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac... | |||
TMPY-00608 |
TGF beta 1 Protein, Rat/Mouse, Recombinant
transforming growth factor, beta 1,transforming gro... |
Mouse,Rat | HEK293 Cells |
TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa. | |||
TMPY-05717 |
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
Integrin alpha V β8,Integrin α V β 8 |
Human | HEK293 Cells |
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This m... | |||
TMPY-02153 |
TNF beta Protein, Human, Recombinant
LT,TNF β,TNFSF1,肿瘤坏死因子,TNFB,lymphotoxin alpha,lymphotoxin α |
Human | E. coli |
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRS... | |||
TMPY-00314 |
Influenza B (B/Yamagata/16/1988) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
Influenza B | Baculovirus Insect Cells |
Influenza B (B/Yamagata/16/1988) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa. | |||
TMPY-06247 |
TGF beta 3 Protein, Human, Recombinant (hFc)
TGF-beta 3,ARVD,TGF β3,TGF-β3,TGF-beta3,tr... |
Human | HEK293 Cells |
TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is P10600-1. | |||
TMPY-02205 |
Beta-Catenin Protein, Human, Recombinant (His & GST)
catenin beta 1,armadillo,CTNNB,MRD19,catenin β1,β-C... |
Human | Baculovirus Insect Cells |
Beta-Catenin Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 113 kDa and the accession number is P35222-1. | |||
TMPY-00413 |
Latent TGF beta 2 Protein, Mouse, Recombinant (His)
Tgfb-2,Tgf-beta2,TGF-beta 2,Tgf-β2,TGFB2,T... |
Mouse | HEK293 Cells |
TGF beta 2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090. | |||
TMPY-03878 |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone... |
Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-01999 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His)
IL-1,IL1-β,白介素,IL1-BETA,白细胞介素,IL1F2,IL-1B,interleuk... |
Human | E. coli |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.3 kDa and the accession number is P01584. | |||
TMPY-00831 |
IFN-beta Protein, Human, Recombinant (hFc)
IFNB,IFN-β,Interferon beta,interferon, beta |
Human | HEK293 Cells |
IFN-beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is A0A7R8GV38. | |||
TMPY-01355 |
Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)
G-α-h,HEL-S-45,TGC,transglutaminase 2,TG2,GNAH,G-AL... |
Human | Baculovirus Insect Cells |
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which... | |||
TMPY-03102 |
IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc)
interleukin 18 receptor accessory protein,IL-18R β/IL-18RAP |
Rhesus | HEK293 Cells |
IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.4 kDa and the accession number is XP_001108108.1. | |||
TMPY-02650 |
Alkaline phosphatase Protein, Human, Recombinant (His)
IAP,alkaline phosphatase, intestinal |
Human | HEK293 Cells |
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is P09923. | |||
TMPY-02603 |
STAT6 Protein, Human, Recombinant (His)
STAT6C,IL-4-STAT,STAT6B,signal tr... |
Human | Baculovirus Insect Cells |
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators... | |||
TMPY-00828 |
Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
MPS2,IDS,SIDS,iduronate 2-sulfatase |
Human | HEK293 Cells |
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an... | |||
TMPY-00500 |
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
transforming growth factor, beta 1,TGF β1,Tgfb-1,TG... |
Mouse | HEK293 Cells |
Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202. | |||
TMPY-02134 |
IL-1 beta/IL-1F2 Protein, Mouse, Recombinant
Il-1b,IL-1beta,白细胞介素,interleukin 1, β,interleukin 1... |
Mouse | E. coli |
IL-1 beta/IL-1F2 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P10749. | |||
TMPJ-00254 |
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
Latency-associated peptide,TGF-beta-3,Transforming ... |
Human,Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regu... | |||
TMPJ-00261 |
TGF beta 2 Protein, Mouse/Rat, Recombinant
transforming growth factor β-2,BSC-1 cell growth inhibitor,G... |
Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n... | |||
TMPK-00639 |
Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His)
GCAP,ALP-1,Alkaline Phosphatase,ALPPL2,PLAP-like,AL... |
Rat | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) is expressed in HEK293... | |||
TMPY-06034 |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
FLG,CD331,N-SAM,HBGFR,HRTFDS,BFGFR,OGD,KAL2,fibroblast growt... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.8 kDa and the accession number is H9FRD4. | |||
TMPY-05716 |
Integrin alpha V beta 3 Protein, Human, Recombinant (His)
Integrin α V β 3,Integrin alpha V β3 |
Human | HEK293 Cells |
Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. | |||
TMPY-01446 |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)
IL-18Rbeta,CD218b,IL-18R β/IL-18RAP,IL-18Rβ,ACPL,IL... |
Human | HEK293 Cells |
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is O95256-1. | |||
TMPJ-00249 |
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TGF-Beta-1,TGFB1,Transforming Growth Factor β-1,Lat... |
Human | HEK293 Cells |
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family... | |||
TMPY-03219 |
VISTA Protein, Human, Recombinant (His)
DD1α,V-set immunoregulatory receptor,SISP1,DD1alpha,B7-H5,PP... |
Human | HEK293 Cells |
VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1. | |||
TMPY-02638 |
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
transforming growth factor, beta 1,转化生长因子,transform... |
Human,Rhesus,Cynomolgus,Canine | CHO Cells |
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.8 kDa and the accession number is A0A499FJK2. | |||
TMPY-03120 |
Prostaglandin D2 Synthase Protein, Human, Recombinant (His)
PDS,L-PGDS,PGDS,PGDS2,LPGDS,PGD2,prostaglandin D2 s... |
Human | HEK293 Cells |
Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222. | |||
TMPY-00130 |
VISTA Protein, Mouse, Recombinant (hFc)
VISTA,V-set immunoregulatory receptor,Dies1,PD-1H |
Mouse | HEK293 Cells |
VISTA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.5 kDa and the accession number is A0A171EBK7. | |||
TMPJ-00258 |
TGF beta 2 Protein, Human, Recombinant
Glioblastoma-derived T-cell suppressor factor,TGF-β-2,Transf... |
Human | HEK293 Cells |
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be... | |||
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