Orthanilamide

Name: Orthanilamide
Brand: TargetMol
SKU: T2187
Price: 123 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.96%

货号 T2187Cas号 3306-62-5

别名 邻氨基苯磺酰胺, O-Sulfanilamide, Benzenesulfonamide, 2-Aminobenzenesulfonamide

Orthanilamide (Orthanilamide) 是一种碳酸酐酶 IX 抑制剂。

Orthanilamide

一键复制产品信息

很棒

纯度: 99.96%

货号 T2187 别名 邻氨基苯磺酰胺, O-Sulfanilamide, Benzenesulfonamide, 2-AminobenzenesulfonamideCas号 3306-62-5

Orthanilamide (Orthanilamide) 是一种碳酸酐酶 IX 抑制剂。

规格	价格	库存
50 mg	¥ 123	现货
100 mg	¥ 163	现货
500 mg	¥ 359	现货
1 g	¥ 518	现货
5 g	¥ 1,260	现货
1 mL x 10 mM (in DMSO)	¥ 138	现货

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产品介绍

Orthanilamide AI Summary

Orthanilamide exhibits bioactivity as an inhibitor of various carbonic anhydrase (CA) enzymes with differing potencies. It shows significant inhibition against human carbonic anhydrase II (Ki = 295.0 nM) and notable activity against human carbonic anhydrase IX (Ki = 33.0 nM). It also demonstrates inhibitory effects on human carbonic anhydrase I (Ki = 45400.0 nM) and bovine carbonic anhydrase IV (Ki = 1310.0 nM). Additionally, Orthanilamide has been observed to inhibit helicobacter pylori recombinant carbonic anhydrase (Ki = 426.0 nM) and exhibits selectivity for different CA isoforms, suggesting potential application as a multi-target CA inhibitor with therapeutic implications..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.
别名	邻氨基苯磺酰胺, O-Sulfanilamide, Benzenesulfonamide, 2-Aminobenzenesulfonamide

化学信息

分子量	172.2
分子式	C₆H₈N₂O₂S
CAS No.	3306-62-5
Smiles	NC1=CC=CC=C1S(N)(=O)=O
密度	1.427g/cm3
颜色	Yellow
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 45 mg/mL (261.32 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (29.04 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.8072 mL	29.0360 mL	58.0720 mL	290.3600 mL
5 mM	1.1614 mL	5.8072 mL	11.6144 mL	58.0720 mL
10 mM	0.5807 mL	2.9036 mL	5.8072 mL	29.0360 mL
20 mM	0.2904 mL	1.4518 mL	2.9036 mL	14.5180 mL
50 mM	0.1161 mL	0.5807 mL	1.1614 mL	5.8072 mL
100 mM	0.0581 mL	0.2904 mL	0.5807 mL	2.9036 mL