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顶部相关产品产品介绍化学信息储存和溶解信息计算器

1-Octadecyl Lysophosphatidic Acid

货号 T36768Cas号 52977-29-4 一键复制产品信息
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1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.

1-Octadecyl Lysophosphatidic Acid

一键复制产品信息
Rating icon 还可以
货号 T36768Cas号 52977-29-4

1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.

1-Octadecyl Lysophosphatidic Acid
规格价格库存数量
500 μg
¥ 659
35日内发货
1 mg
¥ 1,230
35日内发货
5 mg
¥ 4,870
35日内发货
10 mg
¥ 8,420
35日内发货
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产品介绍

生物活性
产品描述
1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.
化学信息
分子量424.559
分子式C21H45O6P
CAS No.52977-29-4
SmilesCCCCCCCCCCCCCCCCCCOCC(O)COP(O)(O)=O
储存&溶解度
存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息
DMSO: 10 mg/mL (23.55 mM), Sonication is recommended.
Ethanol: 10 mg/mL (23.55 mM), Sonication is recommended.
Ethanol:PBS (pH 7.2) ((1:1): 0.5 mg/mL (1.18 mM), Sonication is recommended.
DMF: 10 mg/mL (23.55 mM), Sonication is recommended.
溶液配制表
1mg5mg10mg50mg
1 mM2.3554 mL11.7769 mL23.5539 mL117.7693 mL
DMSO/Ethanol/DMF
1mg5mg10mg50mg
5 mM0.4711 mL2.3554 mL4.7108 mL23.5539 mL
10 mM0.2355 mL1.1777 mL2.3554 mL11.7769 mL
20 mM0.1178 mL0.5888 mL1.1777 mL5.8885 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

1-Octadecyl Lysophosphatidic Acid1Octadecyl Lysophosphatidic Acid1 Octadecyl Lysophosphatidic Acid
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