Name: KRPEP-2D acetate
Brand: TargetMol
SKU: TP2358
Price: 443 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 443

现货

5 mg

¥ 1,170

现货

10 mg

¥ 1,750

现货

25 mg

¥ 2,890

现货

50 mg

¥ 4,130

现货

100 mg

¥ 5,590

现货

200 mg

¥ 7,530

现货

生物活性

产品描述	KRPEP-2D acetate was identified as a K-Ras(G12D) selective inhibitory peptide against the G12D mutant of K-Ras, which is a key member of the Ras protein family and an attractive cancer therapeutic target.
靶点活性	KRas (G12D):1.6 nM
体外活性	KRpep-2d展现出强大的非共价K-Ras(G12D)抑制作用，对于野生型（WT）K-Ras和K-Ras(G12C)突变体具有选择性，在无细胞酶活性（IC50 = 1.6 nM）和基于细胞的测定中均有效。

化学信息

分子量	2621.06
分子式	C₁₁₀H₁₈₆N₄₄O₂₇S₂
Smiles	CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)NC(CSSCC(C(=O)N3CCCC3C(=O)NC(C(=O)NC(C(=O)N1)CC4=CC=C(C=C4)O)CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)[NH-])C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N)C(C)C)CC(=O)O)CC5=CC=C(C=C5)O)CO.[Ac].CC(=O)O
密度	no data available
Sequence	Ac-Arg-Arg-Arg-Arg-Cys-Pro-Leu-Tyr-Ile-Ser-Tyr-Asp-Pro-Val-Cys-Arg-Arg-Arg-Arg (Cys5-Cys15)
Sequence Short	RRRRCPLYISYDPVCRRRR (C5-C15)

储存&溶解度

存储	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.

KRPEP-2D acetate