Name: β-Endorphin (1-27) (human) acetate
Brand: TargetMol
SKU: T38193L
Price: 546 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 546

现货

5 mg

¥ 1,220

现货

10 mg

¥ 1,810

现货

25 mg

¥ 2,880

现货

50 mg

¥ 3,910

现货

100 mg

¥ 5,250

现货

200 mg

¥ 6,900

现货

产品介绍

生物活性

产品描述	β-Endorphin (1-27) (human) acetate, existing in the hypophysis cerebri and hypothalamus, exhibits antinociception activity. β-Endorphin (1-27) (human) acetate is an agonist of opioid receptor, showing preferred affinity for μ-opioid receptor and δ-opioid
体外活性	β-Endorphin (1-27) (human) acetate 通过抑制痛觉传导和减少伤害感受器的激活来施展镇痛效应。该化合物还与高敏感性疼痛时的阿片受体结合，并在脊髓水平上抑制物质P的释放，阻断初级感觉神经元上的痛觉传导。此外，β-Endorphin (1-27) (human) acetate 激活位于中枢神经系统内的内源性镇痛系统[1]。
别名	β-Endorphin (1-27) (human) acetate(76622-84-9 Free base)

化学信息

分子量	3082.52
分子式	C₁₄₁H₂₂₁N₃₃O₄₂S
Smiles	CCC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C1CCCN1C(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(CNC(CNC(C(N)CC2=CC=C(O)C=C2)=O)=O)=O)CC3=CC=CC=C3)=O)CCSC)=O)C(O)C)=O)CO)=O)CCC(O)=O)=O)CCCCN)=O)CO)=O)CCC(N)=O)=O)C(O)C)=O)=O)CC(C)C)=O)C(C)C)=O)C(O)C)=O)CC(C)C)=O)CC4=CC=CC=C4)=O)CCCCN)=O)CC(N)=O)=O)C)=O)C(NC(C(NC(C(NC(C(NC(C(NC(C(O)=O)CC5=CC=C(O)C=C5)=O)C)=O)CC(N)=O)=O)CCCCN)=O)C(CC)C)=O)C.CC(O)=O
Sequence	DL-Tyr-Gly-Gly-DL-Phe-DL-Met-DL-xiThr-DL-Ser-DL-Glu-DL-Lys-DL-Ser-DL-Gln-DL-xiThr-DL-Pro-DL-Leu-DL-Val-DL-xiThr-DL-Leu-DL-Phe-DL-Lys-DL-Asn-DL-Ala-DL-xiIle-DL-xiIle-DL-Lys-DL-Asn-DL-Ala-DL-Tyr
Sequence Short	YGGFMXSEKSQXPLVXLFKNAXXKNAY