Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a vital compound involved in energy storage and metabolism within living organisms. It plays a crucial role in supplying metabolic energy for driving pumps and acts as a coenzyme in cellular processes. Additionally, ATP dipotassium functions as a significant endogenous signaling molecule contributing to immunity and inflammation. 在相同实验条件下,摩尔浓度相同的化合物盐形式与游离态具有相同的生物活性,但盐形式 ATP disodium trihydrate 的水溶性和稳定性通常比游离态更好。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 10,600 | 待询 |
ATP dipotassium 的其他形式现货产品:
产品描述 | ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a vital compound involved in energy storage and metabolism within living organisms. It plays a crucial role in supplying metabolic energy for driving pumps and acts as a coenzyme in cellular processes. Additionally, ATP dipotassium functions as a significant endogenous signaling molecule contributing to immunity and inflammation. |
体外活性 | ATP dipotassium (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs[3]. ATP dipotassium (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner[4]. ATP dipotassium promotes neutrophil chemotaxis in vitro[4]. |
体内活性 | ATP dipotassium (50 mg/kg; i.p.) protects mice against bacterial infection in vivo[4]. ATP dipotassium induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo[4]. Animal Model: Four-week-old Kunming mice (18-22 g)[4]Dosage: 50 mg/kg Administration: Intraperitoneal injection, before bacterial ( E. coli ) challenge Result: Protected mice from bacterial infection. |
别名 | 腺苷三磷酸二钾盐, Adenosine5'-triphosphatedipotassium |
分子量 | 546.28 |
分子式 | C10H16KN5O13P3 |
CAS No. | 42373-41-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
ATP dipotassium 42373-41-1 ATP 腺苷三磷酸二钾盐 Adenosine5'-triphosphatedipotassium Inhibitor inhibitor inhibit