3434
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11693
Cat. No. | Product Name | ||
---|---|---|---|
L7000 | 活性脂质化合物库 | 385 compounds | |
385 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L2620 | 神经退行性疾病化合物库 | 2154 compounds | |
2154 种与神经退行性疾病相关的化合物,可用于高通量和高内涵筛选; | |||
L3980 | DNA损伤/修复库Plus | 667 compounds | |
667 种 DNA 损伤/修复靶向、结构新颖的化合物; | |||
L1510 | 核受体化合物库 | 531 compounds | |
531 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2191 | 抗乳腺癌化合物库 | 1939 compounds | |
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究; | |||
L3800 | NF-κB 通路分子库 | 729 compounds | |
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2550 | 谷氨酰胺代谢化合物库 | 565 compounds | |
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选; | |||
L4300 | Wnt/Hedgehog/Notch 通路化合物库 | 237 compounds | |
237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。 | |||
L4100 | TGF-β/Smad靶点化合物库 | 184 compounds | |
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L3500 | 组蛋白修饰化合物库 | 469 compounds | |
469 个组蛋白修饰相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L3100 | 造血毒性小分子库 | 101 compounds | |
101 种生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L5900 | 血脑屏障通透化合物库 | 509 compounds | |
509 个 CNS-Penetrant 生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L4510 | 抗寄生虫库 | 419 compounds | |
419 种具有抗寄生虫活性的小分子化合物; | |||
L6750 | 活血化瘀中药单体库 | 580 compounds | |
580种来源于常见活血化瘀中药的单体化合物,是药物开发、药理研究等领域的有效工具。 | |||
L7700 | 神经再生化合物库 | 524 compounds | |
524 种神经再生相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L7900 | 成骨分子库 | 317 compounds | |
317 种成骨相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8110 | 细胞重编程化合物库 | 1813 compounds | |
1813 种重编程信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选 | |||
L7500 | 凝血与抗凝化合物库 | 144 compounds | |
144 个化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6740 | 抗结直肠癌中药单体化合物库 | 382 compounds | |
382 种抗结直肠癌相关的中药单体集合,是药物开发、药理研究的有效工具; | |||
L6730 | 抗病毒中药单体化合物库 | 268 compounds | |
268 种具有抗病毒活性的中药单体集合,是药物开发、药理研究的有效工具; | |||
L2196 | 抗卵巢癌化合物库 | 1867 compounds | |
1867 种与卵巢癌相关的化合物,可以用于抗卵巢癌药物研发和药理研究 | |||
L2194 | 抗结直肠癌化合物库 | 1545 compounds | |
1545 种与结直肠癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L2521 | 糖酵解化合物库 | 555 compounds | |
555 种糖酵解相关的活性化合物,可用于高通量和高内涵筛选 | |||
L2193 | 抗肝癌化合物库 | 1787 compounds | |
1787 种与肝癌相关的化合物,可以用于抗肝癌药物研发和药理研究; | |||
L3200 | 自噬库 | 1248 compounds | |
1248 种细胞自噬相关的生物活性小分子化合物的特有集合,用于自噬相关的研究,用于高通量、高内涵筛选; | |||
L9850 | 口服活性化合物库 | 2427 compounds | |
2427 种口服活性化合物独特集合,可用于高通量筛选和高内涵筛选 | |||
L3900 | DNA 损伤和修复分子库 | 910 compounds | |
910 个与 DNA 损伤和修复紧密相关的化合物集合,是高通量筛选,高内涵筛选的良好载体; | |||
L3400 | 临床期小分子药物库 | 3404 compounds | |
3404 个临床期化合物集合,可用于高通量筛选和高内涵筛选; | |||
L2130 | 抗癌细胞代谢库 | 1268 compounds | |
1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合,用于肿瘤相关的研究以及抗肿瘤药物的筛选,用于高通量、高内涵筛选; | |||
L5200 | 抗代谢疾病化合物库 | 1544 compounds | |
1544 个代谢疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L9200 | 药物功能重定位化合物库 | 4630 compounds | |
4630 种全球上市药物和临床药物的独特集合,可用于高通量筛选和高内涵筛选,是老药新用、新的药物靶点筛选和细胞诱导的有效工具。 | |||
L1120 | AMPK靶向分子库 | 80 compounds | |
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选; | |||
L4700 | 免疫/炎症分子化合物库 | 4720 compounds | |
4720 种具有抗炎症活性的化合物的特有集合,可用于高通量筛选和高内涵筛选; | |||
L2120 | 抗癌临床化合物库 | 2545 compounds | |
2545 个具有抗癌活性小分子的独特集合,可用于高通量高内涵筛选。 | |||
L4600 | 植物来源化合物库 | 3048 compounds | |
3048 个植物来源天然产物的独特集合,来自277类植物的精心之选; | |||
L4800 | 血管生成库 | 1353 compounds | |
1353 个高潜力的抑制或促进血管生成的小分子集合,可用于药物靶点开发、血管生成机理研究的高通量筛选,高内涵筛选; | |||
L3700 | JAK-STAT 化合物库 | 252 compounds | |
252 个 JAK/STAT 靶点相关的小分子化合物的独特集合,用于高通量、高内涵筛选; | |||
L2700 | 肾上腺素能受体化合物库 | 193 compounds | |
193 种特异靶向肾上腺素受体的生物活性小分子化合物的集合,是相关疾病药物筛选的有效工具; | |||
L5510 | 肝脏毒性化合物库 | 1001 compounds | |
1001 个肝脏毒性化合物的特有集合,可用于高通量、高内涵筛选,是毒理学研究的良好工具; | |||
L5500 | 毒性化合物库 | 262 compounds | |
262 个细胞毒性化合物的特有集合,可用于高通量、高内涵筛选。 | |||
L7110 | 抗高血压化合物库 | 678 compounds | |
678 种高血压相关的小分子,用于高通量和高内涵筛选; | |||
L8500 | HIF-1化合物库 | 1336 compounds | |
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究; | |||
L8100 | 细胞周期化合物库 | 677 compounds | |
677 种细胞周期相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L1520 | 膜蛋白靶向化合物库 | 4175 compounds | |
L2510 | 脂代谢化合物库 | 492 compounds | |
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选; | |||
L6810 | 中药单体化合物库 | 2755 compounds | |
2755 种中药来源的单体化合物,是药物开发、药理研究等领域的有力工具; | |||
L4150 | 新颖已知活性精选库 | 989 compounds | |
989 种百里挑一的活性化合物; | |||
L9700 | 内质网应激化合物库 | 193 compounds | |
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选; | |||
L1110 | 微管靶向化合物库 | 142 compounds | |
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选; | |||
L1310 | 细胞骨架化合物库 | 759 compounds | |
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选; | |||
L2400 | 内分泌激素分子库 | 784 compounds | |
784 种与内分泌系统相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2530 | 小鼠代谢化合物库 | 218 compounds | |
218 种小鼠代谢化合物的集合,可用于高通量筛选和高内涵筛选; | |||
L3510 | 甲基化化合物库 | 128 compounds | |
128 种甲基化相关的化合物,可以用于高通量和高内涵筛选; | |||
L2800 | 5-羟色胺分子库 | 268 compounds | |
268 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L2910 | 抗氧化化合物库 | 1314 compounds | |
氧化应激(Oxidative Stress,OS)是指体内氧化与抗氧化作用失衡的一种状态。氧化应激导致活性氧(ROS)大量积累,氧化程度超出抗氧化物的清除能力,从而引起氧化损伤,氧化应激损伤是许多疾病发生的基础,不同程度的氧化应激造成的细胞效应与心脑血管疾病、神经退行性病变、炎症和肿瘤密切相关。抗氧化剂是一类能够对抗氧化应激,降低氧化损伤的一类化合物。 TargetMol 抗氧化化合物库是1314 种对氧化应激具有抑制作用的小分子特有集合,是研究氧化应激的有用工具,可以用于高通量筛选和高内涵筛选。 | |||
L4500 | 抗真菌库 | 252 compounds | |
252 个抗真菌活性化合物的独特集合,包含作用于真菌相关靶点的化合物和临床中用于真菌类疾病的药物,是相关疾病药物筛选的有效工具。 | |||
L3410 | 临床前化合物库 | 701 compounds | |
701 种临床前小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6230 | 苗药化合物库 | 534 compounds | |
534种苗族特色药材的天然产物分子,可用于高通量和高内涵筛选 | |||
L8400 | 血液病分子库 | 514 compounds | |
514 种造血系统疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8700 | 铁死亡化合物库 | 779 compounds | |
779 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选; | |||
L8300 | 染色质修饰分子库 | 250 compounds | |
250 种染色质化学修饰相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L9830 | 抗帕金森病化合物库 | 857 compounds | |
857 种帕金森病相关的化合物集合,可用于高通量和高内涵筛选; | |||
L9820 | β-内酰胺类化合物库 | 97 compounds | |
97 种β-内酰胺类化合物的集合,可以用于高通量和高内涵筛选; | |||
L9840 | 抗阿尔茨海默症化合物库 | 986 compounds | |
986 种阿尔茨海默症相关的化合物集合,可用于高通量和高内涵筛选; | |||
L4710 | 非甾体类抗炎化合物库 | 530 compounds | |
530 种非甾体类的抗炎相关化合物,可用于高通量和高内涵筛选; | |||
L6210 | 藏药化合物库 | 747 compounds | |
747 种藏药来源的天然产物分子集合,可以用于高通量和高内涵筛选; | |||
L2610 | 神经递质受体化合物库 | 1513 compounds | |
1513 种与神经递质受体相关的化合物,用于高通量、高内涵筛选; | |||
L5400 | 抗心血管疾病化合物库 | 1408 compounds | |
1408 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L1900 | 抗糖尿病库 | 683 compounds | |
683 种生物活性小分子化合物; | |||
L2501 | 人内源代谢化合物库 Plus | 1283 compounds | |
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。 | |||
L1500 | GPCR靶点分子库 | 1940 compounds | |
1940 种与 G 蛋白及其耦联受体相关的生物活性小分子化合物,所有小分子都具有良好的生物和药理活性,部分是 FDA 批准的上市药物; | |||
L9700 | 内质网应激化合物库 | 193 compounds | |
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选; | |||
L1110 | 微管靶向化合物库 | 142 compounds | |
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选; | |||
L1310 | 细胞骨架化合物库 | 759 compounds | |
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选; | |||
L4020 | NO PAINS 化合物库 | 9384 compounds | |
TargetMol NO PAINS 化合物库包含 9384 个剔除了PAINS 的小分子活性化合物,可用于新药研发,信号通路研究,老药新用等研究。 | |||
L1800 | 抗感染化合物库 | 2938 compounds | |
2938 种具有抗感染活性的化合物的特有集合,包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性; | |||
L2140 | 癌细胞分化化合物库 | 406 compounds | |
406 个诱导肿瘤细胞分化化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2192 | 抗胰腺癌化合物库 | 2238 compounds | |
2238 种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L2900 | 氧化还原化合物库 | 1264 compounds | |
1264 个活性化合物,已经验证具有一定的抗氧化活性,包括 ROS 清除剂、iNOS、eNOS、及抗氧化的天然产物,是研究疾病机理以及药物研究的优良载体 | |||
L4900 | 心血管毒性化合物库 | 131 compounds | |
131 种心血管毒性化合物的独特集合,可用于毒理学研究; | |||
L6300 | 药食同源库 | 1290 compounds | |
1290 个药食同源化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6710 | 中药抗炎分子库 | 1246 compounds | |
1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具; | |||
L7200 | 钙通道分子库 | 140 compounds | |
140 种钙通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L9300 | 大环化合物库 | 210 compounds | |
210 种活性已知的大环化合物,用于高通量、高内涵筛选; | |||
L9000 | 细胞凋亡化合物库 | 1760 compounds | |
1760 种与凋亡相关的生物活性小分子化合物的特有集合,多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选; | |||
L8200 | 抗衰老化合物库 | 3279 compounds | |
3279 个抗衰老化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2630 | 神经元分化化合物库 | 672 compounds | |
672 种与神经元分化相关的化合物,可以用于神经系统疾病药物研发 | |||
L2195 | 抗前列腺癌化合物库 | 2070 compounds | |
2070 种与前列腺癌相关的化合物,可以用于高通量和高内涵筛选 | |||
L4520 | 抗菌活性库 | 904 compounds | |
904 种具有抗菌活性的化合物,是抗菌药物研发的有力工具; | |||
L8000 | 干细胞分化化合物库 | 1197 compounds | |
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选; | |||
L5300 | 线粒体靶向库 | 812 compounds | |
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究; | |||
L7100 | 抗肥胖化合物库 | 2247 compounds | |
2247 个抗肥胖化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2100 | 抗癌化合物库 | 7234 compounds | |
7234 种肿瘤相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L4000 | 经典已知活性库 | 14439 compounds | |
14439 个已知活性化合物的集合,可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认; | |||
D7800 | 新颖已知活性库 | 8118 compounds | |
提高成功率:新增8118种已知活性化合物,提高实验成功率。 | |||
L2180 | 抗肿瘤库Plus | 1468 compounds | |
1468 种抗肿瘤相关、结构新颖的化合物; | |||
L1380 | 转录因子库 | 695 compounds | |
695 种转录因子靶向、结构新颖的化合物; | |||
L1710 | 抗COVID-19化合物库 | 1133 compounds | |
1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选; | |||
L3300 | 组胺&褪黑色素化合物库 | 153 compounds | |
153 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L9420 | 外泌体相关化合物库 | 76 compounds | |
76 种外泌体相关的化合物,可以用于高通量和高内涵筛选; | |||
L8600 | 泛素化化合物库 | 210 compounds | |
210 种泛素化相关的小分子,用于高通量和高内涵筛选; | |||
L8710 | 铜死亡化合物库 | 400 compounds | |
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究 | |||
L9860 | 抗抑郁症化合物库 | 1163 compounds | |
1163 种与抑郁症相关的化合物,可以用于高通量和高内涵筛选 | |||
L6820 | 烟草单体化合物库 | 747 compounds | |
747种烟草单体化合物的独特集合,可用于高通量筛选和高内涵筛选 | |||
L2560 | 代谢化合物库 | 2320 compounds | |
2320 种代谢途径相关的化合物,可用于高通量和高内涵筛选。 | |||
L9810 | 抗纤维化化合物库 | 1180 compounds | |
1180 种潜在的抗纤维化分子,是研究纤维化的有效工具,可以用于高通量筛选和高内涵筛选; | |||
L2190 | 抗肺癌化合物库 | 1702 compounds | |
1702 种与肺癌相关的化合物,可以用于抗肺癌药物研发和药理研究; | |||
L1200 | 表观遗传库 | 953 compounds | |
953 种表观遗传学研究相关的生物活性小分子的特有集合,用于表观遗传学研究及其相关的检测和高通量、高内涵筛选; | |||
L1720 | 核苷类化合物库 | 334 compounds | |
334 种核苷类化合物,包括核苷酸、核苷酸类似物及衍生物等,适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发; | |||
L6220 | 蒙药化合物库 | 950 compounds | |
950 种蒙药来源的天然产物分子集合,可以用于高通量和高内涵筛选; | |||
L8720 | 细胞焦亡化合物库 | 1066 compounds | |
1066 种细胞焦亡相关的化合物,可以用于细胞焦亡相关研究。 | |||
L2170 | 肿瘤免疫治疗小分子化合物库 | 449 compounds | |
449 种靶向肿瘤免疫治疗靶点的小分子,可用于高通量和高内涵筛选,是研究肿瘤免疫治疗的有力工具; | |||
L9600 | 多肽分子库 | 791 compounds | |
791 种多肽类分子,可用于多肽药物开发及信号转导通路和作用机制研究; | |||
L6720 | 抗COVID-19中药单体库 | 1147 compounds | |
根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂,收集了1147 种相关中药来源的单体化合物,可用于高通量和高内涵筛选,是抗新冠病毒药物研发的良好工具; | |||
L2600 | 神经信号分子库 | 2540 compounds | |
2540 种CNS 相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L1700 | 抗病毒库 | 1040 compounds | |
1040 种具有抗病毒活性的化合物的特有集合,是筛选新型抗病毒药的有效工具;可用于高通量筛选和高内涵筛选; | |||
L2160 | 抗癌活性化合物库 | 3188 compounds | |
3188 种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选; | |||
L4010 | 已知活性化合物库 | 22555 compounds | |
22555 个已知活性化合物的集合,可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0502 |
Zinc pyrithione
吡硫锌,OM-1563,吡啶硫酮锌 |
Proton pump; Antibacterial; Antifungal | Membrane transporter/Ion channel; Microbiology/Virology |
Zinc pyrithione (OM-1563) 通过阻断质子泵破坏膜转运,具有抗真菌和细菌作用。 | |||
T71875 |
OM-137
|
||
OM137 is an inhibitor of Aurora kinases. which is growth inhibitory to cultured cells when applied at high concentration and potentiates the growth inhibitory effects of subnanomolar concentrations of paclitaxel. | |||
T12301 | OM-189 | Thrombin | Proteases/Proteasome |
OM-189 is a selective inhibitor of synthetic thrombin. | |||
T23634 |
Adecypenol
OM-3223,OM3223,OM 3223,Antibiotic OM 3223 |
||
Adecypenol is a unique adenosine deaminase inhibitor. It shows effective inhibitory activity against calf intestinal adenosine deaminase. | |||
T62869 |
OM-1700
|
||
OM-1700 是一种 tankyrase 的有效抑制剂,作用于 tankyrase 1 (IC50: 127 nM) 和 tankyrase 2 (IC50: 14 nM)。OM-1700 能够抑制结肠癌细胞系的生长,抑制 COLO 320DM 细胞 (GI50: 650 nM)。 | |||
T71367 |
OM-4842
|
||
OM-4842 is a platelet aggregation inhibitor from Streptomyces. | |||
T63508 |
OM-153
|
||
OM-153 是 tankyrase 的有效抑制剂,能够作用于 tankyrase 1 (IC50: 13 nM) 和 tankyrase 2 (IC50: 2 nM),且对 COLO 320DM 中的 WNT/β-连环蛋白信号传导和增殖具有抑制作用。 | |||
T40393 |
OM99-2
OM99-2 |
||
OM99-2 is an eight-residue peptidomimetic with a high affinity for human brain memapsin 2, exhibiting a Ki value of 9.58 nM. This compound represents a significant advancement in the development of BACE1 inhibitors and holds potential for the study of Alzheimer's disease. | |||
T124003 |
Antibiotic OM 173?2
|
||
Antibiotic OM 173?2 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124003,CAS号为 88293-10-1。 | |||
T40165 |
OM99-2 TFA
OM99-2 TFA |
||
OM99-2 TFA is an eight-residue peptidomimetic compound, functioning as a tight-binding inhibitor of human brain memapsin 2. It exhibits a high affinity for the target with a Ki value of 9.58 nM, making it a promising candidate in the development of BACE1 inhibitors. Due to its potential, OM99-2 presents opportunities for further research in the field of Alzheimer's disease. | |||
T22534 |
8-Hydroxy-DPAT hydrobromide
7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐,8-OH-DPAT hydrobromide |
5-HT Receptor | GPCR/G Protein; Neuroscience |
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) 是一种选择性5-HT1A 激动剂,pIC50为 8.19。它对 5-HT1结合位点的亚型有近 1000 倍的选择性。 | |||
T1522 |
Iopromide
碘普罗胺,Iopromidum,Ultravist |
Others | Others |
Iopromide (Iopromidum) 是用于血管内的低渗透、非离子造影剂。 | |||
T0023 |
Valethamate bromide
Ediposin,Epidozin,戊沙溴铵,Epidosin,Resitan |
Others | Others |
Valethamate bromide (Resitan) 是快速作用的抗胆碱能解痉和肌萎缩剂,是一种酯,能够改善宫颈扩张加速分娩。 | |||
T6897 |
Monomethyl auristatin E
一甲基澳瑞他汀E,Vedotin,MMAE |
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Monomethyl auristatin E (MMAE) 是海兔毒素 10 的合成衍生物,是一种抗有丝分裂剂,通过阻断微管蛋白的聚合来抑制细胞分裂,并且还具有抑制抗体-药物偶联物的活性。 | |||
T76975 |
Tomaralimab
OPN-305 |
TLR | Immunology/Inflammation |
Tomaralimab (OPN-305) 是一种人源化的靶向 TLR2 的 IgG4 单克隆抗体。Tomaralimab 可用于研究骨髓增生异常综合征 (MDS) 。 | |||
T77771 |
Compound 10w
|
Others | Others |
Compound 10w,一种取代吡唑并[1,5-a]嘧啶酰胺化合物,是一种ZSTK474 类似物,对 HeLa细胞显示出抗癌活性。 | |||
T33828 |
O-Succinylhomoserine
O-琥珀酰-L-高丝氨酸,O-Succinyl-L-homoserine |
Others | Others |
O-Succinylhomoserine (O-Succinyl-L-homoserine) 是大肠杆菌合成胱硫醚的中间体。 | |||
T77912 |
Tz-Thalidomide
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
Tz-Thalidomide 是一种四嗪修饰的 Thalidomide(E3连接酶配体),对 BRD4 具有一定的亲和力。 | |||
T20626 |
Esomeprazole
|
Proton pump; Cysteine Protease | Membrane transporter/Ion channel; Proteases/Proteasome |
Esomeprazole 是奥美拉唑(omeprazole) 的S-异构体,抑制溶酶体半胱氨酸蛋白酶legumain,防止癌症转移。它是一种质子泵抑制剂(PPI)。 | |||
T8891 |
Homo-VK-II-36
Homo-V-II-36 |
Others | Others |
Homo-VK-II-36 (Homo-V-II-36) 是一种卡维地洛类似物,其作用是通过 RyR2 通道抑制储存超载诱导的钙释放。 | |||
T19733 |
Prometryn
Caparol,Gesagard,Mercazin,扑草净 |
Others | Others |
Prometryn (Mercazin) 是一种除草剂,可提高棉花产量。 | |||
T6286 |
RGFP966 (E-isomer)
|
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
RGFP966 是一种 HDAC3 抑制剂,IC50 为 0.08 μM,比其他 HDAC 选择性高 200 倍以上。 | |||
T7454 |
4-Bromo-3-hydroxybenzoic acid
|
Decarboxylase; Endogenous Metabolite | Metabolism; Others |
4-Bromo-3-hydroxybenzoic acid 是一种组氨酸脱羧酶抑制剂,是一种 Brocresine 的代谢产物,对大鼠胎儿和大鼠胃HDC 的IC50均为 1 mM。它还能够在体外抑制猪肾脏和大鼠胃粘膜中的芳香族 L-氨基酸脱羧酶,两种酶的IC50均为 1 mM。 | |||
T5882 |
3-Bromopyruvic acid
Hexokinase II Inhibitor II, 3-BP,3-溴丙酮酸,Bromopyruvic acid |
Apoptosis; Hexokinase; Autophagy | Apoptosis; Autophagy; Metabolism |
3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) 是己糖激酶 II 抑制剂,是针对肝癌细胞的一种抗肿瘤剂。 | |||
T11758 |
KI696 isomer
|
Nrf2 | Immunology/Inflammation |
KI696 isomer 是 KI696 的异构体,是一种亲和力较低的探针,可用于研究免疫和代谢疾病。 | |||
T40030 |
Thalidomide 4'-ether-alkylC2-amine hydrochloride
halidomide-linker 6 |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) 包含基于 Thalidomide 的 cereblon 配体和 linker,是合成的 E3 连接酶配体-linker 偶联物,可应用于 PROTAC 技术。 | |||
T13612 |
Chromafenozide
2'-叔丁基-5-甲基-2'-(3,5-二甲基苯甲酰基)色满-6-甲酰肼,环虫酰肼,ANS118 |
Others | Others |
Chromafenozide (ANS118) 是一种鳞翅目昆虫的杀虫剂,能高效地控制多种鳞翅目害虫。 | |||
T18831 |
Thalidomide-propargyl
|
Others; Ligand for E3 Ligase | Others; PROTAC |
Thalidomide-propargyl 是一种基于 Thalidomide 的 Cereblon 配体,可用于募集 CRBN 蛋白。它能够利用 linker 与靶蛋白配体连接,得到含 IMiD 的 PROTAC。 | |||
T35805 |
C16 Sphingomyelin (d18:1/16:0)
Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin |
Endogenous Metabolite | Metabolism |
C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) 是磷脂双层膜的磷脂类化合物,可用于研究生物膜的活性。 | |||
T38398 |
Abrucomstat
3-Nitroxypropanol,3-NOP |
Others | Others |
Abrucomstat (3-NOP) 作为一种酶抑制剂,可减少瘤胃产甲烷作用。 | |||
T22761 |
EIT hydrobromide
2-Ethyl-2-thiopseudourea hydrobromide,S-Ethylisothiourea hydrobromide,S-乙基硫酸乙烯溴化氢 |
NOS | Immunology/Inflammation |
EIT hydrobromide (S-Ethylisothiourea hydrobromide) 是一种iNOS 抑制剂。 | |||
T12081 |
MMAF-OMe
Monomethyl auristatin F methyl ester |
||
MMAF-OMe (Monomethyl auristatin F methyl ester) 是一种抗微管蛋白剂,能够抑制 MDAMB435/5T4,MDAMB361DYT2,MDAMB468 和 Raji (5T4-) 这四种肿瘤细胞,IC50值分别为 0.056 nM,0.166 nM,0.183 nM 和 0.449 nM。它也是ADC 细胞毒素。 | |||
T37742 |
N-hexanoyl-DL-Homoserine lactone
C6-HSL |
Antibiotic | Microbiology/Virology |
N-hexanoyl-DL-Homoserine lactone (C6-HSL) 是从双壳类幼虫培养物中分离出来的,可降解细菌,可抑制植物病原真菌 B. cinerea 诱导的病变。N-hexanoyl-DL-Homoserine lactone 参与细菌间的N-酰基-高丝氨酸内酯 (AHL) 群体感应 (QS) 系统。 | |||
T0264 |
Zomepirac sodium salt
Zomepirac Sodium,佐美酸钠,McN-2783-21-98 |
PGE Synthase; PDE | Immunology/Inflammation; Metabolism |
Zomepirac sodium salt (McN-2783-21-98) 是前列腺素合成酶抑制剂。它是一种非甾体抗炎药,但能够导致免疫介导的肝损伤。 | |||
T2707 |
Pifithrin-α hydrobromide
Pifithrin hydrobromide,Pifithrin-α (PFTα) HBr,Pifithrin-α,PFTα,PFTα hydrobromide |
Ferroptosis; Aryl Hydrocarbon Receptor; p53 | Apoptosis; Immunology/Inflammation |
Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) 是一种 p53 抑制剂,可抑制 p53 反应基因的 p53 依赖性反式激活。它也是芳烃受体的激动剂。 | |||
T13789 |
N-dodecanoyl-L-Homoserine lactone
C12-HSL,十二烷酰-L-高丝氨酸内酯 |
Others | Others |
N-dodecanoyl-L-Homoserine lactone (C12-HSL) 是群体感应 (QS) 信号分子的一种。它适配体可用于阻止群体感应,并能够阻碍铜绿假单胞菌 (Pseudomonas aeruginosa) 生物膜的形成。 | |||
T7206L |
2-Iminobiotin hydrobromide
2-亚氨基生物素,Guanidinobiotin,2-亚氨基生物素盐酸盐 |
NOS; NO Synthase | Immunology/Inflammation |
2-Iminobiotin hydrobromide (Guanidinobiotin) 是生物素 (维生素 H 或 B7) 类似物。它是一种可逆的 NO 合酶抑制剂,可作用于小鼠 iNOS(Ki:21.8 μM)和大鼠 n-cNOS(Ki:37.5 μM)。它和低温环境均可以保护人类神经细胞,使其免受缺氧诱导的细胞损伤。 | |||
T7003 |
Leucomethylene blue mesylate
N3,N3,N7,N7-四甲基-10H-吩噻嗪-3,7-二胺二甲磺酸盐,TRx0237 mesylate,TRx0237 (LMTX) mesylate,Methylene blue leuco base mesylate salt,Leucomethylene Blue Dimesylate |
Beta Amyloid; Microtubule Associated | Cytoskeletal Signaling; Neuroscience |
Leucomethylene blue mesylate (TRx0237 mesylate) 是一种 Methylene blue (亚甲基蓝)的还原形式, 亚甲基蓝是一种化学指示剂和生物染色剂。它是一种具有口服活性的二代 tau 蛋白聚集的抑制剂 (Ki=为0.12 μM),可用于阿尔兹海默症的研究。 | |||
T22375 |
N-hexanoyl-L-Homoserine lactone
己酰-L-高丝氨酸内酯,C6-HSL |
Others; Antibacterial | Microbiology/Virology; Others |
N-hexanoyl-L-Homoserine lactone (C6-HSL) 是一种可扩散信号分子,参与控制基因表达、影响细胞代谢和群体感应。 | |||
T16684 |
Puromycin aminonucleoside
维生素E醋酸酯,NSC 3056 |
Apoptosis; Proteasome; Aminopeptidase; Antibacterial; Antibiotic | Apoptosis; Metabolism; Microbiology/Virology; Proteases/Proteasome; Ubiquitination |
Puromycin aminonucleoside (NSC-3056) 是一种氨基核苷类抗生素,是嘌呤霉素类似物。它可逆抑制二肽基肽酶和胞浆丙氨酸氨基肽酶。它通过以氧化应激依赖性方式调节 ZO-1 来增加足细胞通透性。它诱导细胞凋亡 。 | |||
T21463 |
Temozolomide Acid
TMZA,3,4-二氢-3-甲基-4-氧代咪唑并[5,1-D]-1,2,3,5-四嗪-8-甲酰胺酸 |
Others | Others |
Temozolomide Acid (TMZA) 是 temozolomide (TMZ) 的代谢物。TMZ 在体外具有抗癌活性。TMZ 是一种口服烷化剂,用于治疗多形性胶质母细胞瘤 (GBM) 和星形细胞瘤。 | |||
T11593 |
I-OMe-Tyrphostin AG 538
I-OMe-AG 538 |
IGF-1R; PI3K | PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
I-OMe-Tyrphostin AG 538是一种特异性 IGF-1R 抑制剂和 PI5P4Kα的 ATP 竞争性抑制剂(IC50:1 µM)。I-OMe-Tyrphostin AG 538可抑制 IGF-1R 介导的信号传导,并对营养缺乏的 PANC1细胞具有优先细胞毒性。 | |||
T14960 |
Chroman 1
|
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
Chroman 1 是高效的的ROCK 选择性抑制剂,对 ROCK2 (IC50=1 pM) 的抑制作用强于 ROCK1 (IC50=52 pM) 。它对MRCK 也有抑制作用,IC50为 150 nM。 | |||
T21685 |
CCT 031374 hydrobromide
|
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
CCT 031374 hydrobromide 是一种 TCF/β-catenin 抑制剂,具有抗肿瘤活性。 | |||
T39585 |
Ziftomenib
KO-539 |
Histone Methyltransferase | Chromatin/Epigenetic |
Ziftomenib (KO-539) 是一种具有抗肿瘤活性的 menin-MLL 相互作用抑制剂,可以用于研究白血病。 | |||
T2495 |
Lomeguatrib
罗米鲁曲,PaTrin-2 |
DNA Methyltransferase; DNA Alkylation | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Lomeguatrib (PaTrin-2) 是修饰鸟嘌呤碱基,是MGMT 有效抑制剂,可抑制 DNA 修复蛋白 O(6)-烷基鸟嘌呤-DNA 烷基转移酶 (MGMT) 的活性。在非细胞体系和 MCF-7 细胞体系中,IC50值分别为 9 nM 和约 6 nM。 | |||
T4477 |
Domatinostat tosylate
4SC-202 tosylate,4SC-202 |
Apoptosis; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair |
Domatinostat tosylate (4SC-202) 是一种 I 型 HDAC 抑制剂,能够抑制 HDAC1、HDAC2和 HDAC3 的活性,IC50值分别为 1.20 μM、1.12 μM 和 0.57 μM。它也抑制组蛋白赖氨酸特异性脱甲基酶1 的活性。 | |||
T27632 |
Isomazole
|
PDE | Metabolism |
Isomazole 是一种可口服的具有钙敏特性的新型磷酸二酯酶(PDE)抑制剂,对PDE3 和 PDE4 有抑制作用。 | |||
T13210 |
Trombodipine
PCA-4230 |
Antibiotic | Microbiology/Virology |
Trombodipine (PCA-4230) 是一种血小板聚集抑制剂,具有抗血栓活性,对单核细胞增生李斯特菌具有保护作用。 | |||
TP1106L |
α-Factor Mating Pheromone, yeast acetate
Mating Factor α acetate,α-Factor Mating Pheromone, yeast acetate(59401-28-4 free base) |
Others | Others |
α-Factor Mating Pheromone, yeast acetate (Mating Factor α acetate)(59401-28-4 free base) 是由酿酒酵母α细胞分泌的13个氨基酸的肽。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T69058 |
OM173-αA
|
||
OM173-αA is a quinone bacterial metabolite that inhibits the growth of the bacteria M. gallisepticum, M. pneumoniae, and S. aureus. OM173-αA also inhibits the growth of the plant pathogenic fungus P. oryzae and several species of Trichophyton. | |||
T16542 |
Piromidic acid
吡咯酸,吡乙酸三氮萘 |
Antibacterial; Antibiotic | Microbiology/Virology |
Piromidic acid 是一种抗菌剂。它对革兰氏阴性菌和葡萄球菌具有活性,可研究肠道,泌尿和胆道感染。 | |||
T4877 |
L-Homocystine
|
Endogenous Metabolite | Metabolism |
L-Homocystine 是一种 L-homocysteine 的氧化物。其中 L-homocysteine 是抗血栓因子、血管舒张损害剂、促炎因子,也是研究心血管疾病发生机制的内质网应激反应的诱导剂。 | |||
T5244 |
Aminomalonic acid
2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate |
Others; Endogenous Metabolite | Metabolism; Others |
Aminomalonic acid (Aminomalonate) 是氨基内源性代谢产物,在体外能作为来源 Leukemia 5178Y/AR 和小鼠胰腺的 L- 天冬酰胺合成酶的高效抑制剂 (Leukemia 5178Y/AR:Ki= 0.0023 M,小鼠胰腺:Ki= 0.0015 M)。它有潜力用作区分黑素瘤转移的不同阶段生物标志物。 | |||
TN1482 |
Chamaechromone
|
P450; HBV | Metabolism; Microbiology/Virology |
Chamaechromone 是从 Stellera chamaejasme L. 的根中分离出来的天然产物。 Chamaechromone 具有抗 HBV 和杀虫活性。 | |||
TQ0215 |
Salinomycin sodium salt
盐霉素钠,Sodium salinomycin,Salinomycin sodium |
Apoptosis; Wnt/beta-catenin; Antibacterial; Antibiotic; Autophagy | Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Stem Cells |
Salinomycin sodium salt (Sodium salinomycin) 是钾离子载体抗生素,是作用于 Wnt/Fzd/LRP 复合物的Wnt/β-catenin 信号传导抑制剂,能阻断 Wnt 诱导的 LRP6 磷酸化,导致 LRP6 蛋白降解。它选择性抑制人肿瘤干细胞。 | |||
T7027 |
EURYCOMANONE
东革阿里提取物,Pasakbumin A |
Others | Others |
Eurycomanone (Pasakbumin A) 能够抑制雌激素生成过程中磷酸二酯酶和芳香酶的活性,促进精子生成。它对 HepG2 细胞具有细胞毒性,能够上调 p53 和 Bax 以及下调 Bcl-2 ,诱导细胞凋亡。它具有抗癌活性,在浓度范围内以剂量依赖性方式抑制 A549 肺癌细胞增殖 从 5 到 20 微克/毫升。 | |||
T8247 |
(+)-Aromadendrene
|
Anti-infection | Microbiology/Virology |
(+)-Aromadendrene 是一种天然产物,对革兰氏阳性菌和革兰氏阴性菌具有显着的抗菌活性。 | |||
TN6967 |
(R)-Isomucronulatol
(-)-Isomucronulatol,2H-1-Benzopyran-7-ol |
Apoptosis | Apoptosis |
(R)-Isomucronulatol (2H-1-Benzopyran-7-ol) 是一种可从黄芪、刺槐、虎杖和甘草叶片中提取得到的类黄酮,抑制BMSCs 在TNF-α微环境中的增殖和凋亡。(R)-Isomucronulatol 具有潜在的抗炎活性。 | |||
TN7163 |
Methyl 4-bromopyrrole-2-carboxylate
4-Bromo-2-(methoxycarbonyl)-1H-pyrrole,methyl 4-bromo-1H-pyrrole-2-carboxylate,4-溴-1H-吡咯-2-羧酸甲酯 |
Others | Others |
Methyl 4-bromopyrrole-2-carboxylate (4-Bromo-2-(methoxycarbonyl)-1H-pyrrole) 是一种海洋来源的天然产物,存在于 Lissodendoryx sp.。 | |||
TN7180 |
2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)-
4-(5-溴-1H-吲哚-3-基)嘧啶-2-胺,Meridianin C |
Others | Others |
2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)- (Meridianin C)是一种海洋来源的天然产物,存在于Aplidium meridianum。 | |||
TN7155 |
Methyl 3-bromo-4,5-dihydroxybenzoate
Methyl 3,4-dihydroxy-5-bromobenzoate,3-bromo-4,5-dihydroxybenzoic acid methyl ester |
Others | Others |
Methyl 3-bromo-4,5-dihydroxybenzoate (3-bromo-4,5-dihydroxybenzoic acid methyl ester) 是一种海洋来源的天然产物,存在于 Rhodomela confervoides。 | |||
TN7196 |
5,6-dibromo-1H-indole-3-carboxylic acid
5,6-dibromo-1H-indole-3-carboxylicAcid,5,6-二溴-1H-吲哚-3-羧酸,ZINC4219119 |
Others | Others |
5,6-dibromo-1H-indole-3-carboxylic acid (5,6-dibromo-1H-indole-3-carboxylicAcid) 是一种海洋来源的天然产物,存在于 Smenospongia sp.。 | |||
TN1785 |
Isomagnolone
|
Others | Others |
Isomagnolone 是一种分离自八角茴香中的天然产物,具有抗炎作用。 | |||
TN7192 |
7-Bromoquinazoline-2,4(1H,3H)-Dione
7-Bromo-2,4(1H,3H)-quinazolinedione,7-溴喹唑啉-(2,4)二酮,7-Bromo-1H-quinazoline-2,4-dione,7-bromoquinazoline-2,4-diol |
Others | Others |
7-Bromoquinazoline-2,4(1H,3H)-Dione (7-Bromo-2,4(1H,3H)-quinazolinedione) 是一种海洋来源的天然产物,发现于 Pyura sacciformis。 | |||
T0086 |
Galanthamine hydrobromide
Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏 |
AChR; AChE | Neuroscience |
Galanthamine hydrobromide (Galantamine hydrobromide) 是一种长效的中枢活性 AChE 抑制剂,IC50为 410 nM。它是神经元烟碱型 ACh 受体的变构增强剂,IC50值为 0.35 µM,可用于阿尔茨海默症的研究。 | |||
T3804 |
Neomangiferin
Mangiferin 7-glucoside,新芒果苷 |
Phosphatase | Metabolism |
Neomangiferin (Mangiferin 7-glucoside) 是一种天然的 C-glucosyl xanthone,分离自干燥的Anemarrhena asphodeloides 的根茎中。它能够减轻大鼠高脂饮食诱导的非酒精性脂肪性肝病 (NAFLD)。 | |||
T6212 |
Combretastatin A4
CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09 |
Microtubule Associated | Cytoskeletal Signaling |
Combretastatin A4 (CA4) 是一种微管靶向剂,可结合 β-tubulin,Kd 值为 0.4 μM。 | |||
T19808 |
5-Bromo-5-nitro-1,3-dioxane
Bronidox,5-溴-5-硝基-1,3-二噁烷,5-溴-5-硝基-1,3-二恶烷 |
Others; Antibacterial; Antifungal | Microbiology/Virology; Others |
5-Bromo-5-nitro-1,3-dioxane (Bronidox) 是一种抗菌化合物,可通过必需蛋白硫醇的氧化抑制酶活性并随后抑制微生物的生长。它有抗革兰氏阳性和革兰氏阴性细菌,以及抗真菌活性。 | |||
T1235 |
Lincomycin hydrochloride monohydrate
洁霉素盐酸盐,林可霉素,Lincomycin hydrochloride hydrate |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Lincomycin hydrochloride monohydrate (Lincomycin hydrochloride hydrate) 是一种窄谱抗生素, 具有与红霉素相似的效力, 对革兰氏阳性球菌的作用效果很好, 主要抑制细菌细胞蛋白质的合成。 | |||
T12564 |
Prudomestin
3,5,7-Trihydroxy-4',8-dimethoxyflavone,3,5,7-三羟基-8,4'-二甲氧基黄酮 |
Xanthine Oxidase | Metabolism |
Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) 是一种分离自 Prunus domestica 心材中,具有很强的黄嘌呤氧化酶(XO)抑制活性(IC50≈6 µM)。 | |||
T3786 |
Tomatine
lycopersicin,番茄素,番茄碱 |
Apoptosis; Proteasome | Apoptosis; Proteases/Proteasome; Ubiquitination |
Tomatine (lycopersicin) 是从番茄植物中发现的一种糖苷生物碱。它促进神经母细胞瘤细胞中核凋亡诱导因子的上调,还抑制20S 蛋白酶体活性。它以 RIP1 激酶和 caspase 非依赖性的方式引发神经毒性。 | |||
T8641 |
Vancomycin
|
Antibacterial; Antibiotic; Autophagy | Autophagy; Microbiology/Virology |
Vancomycin 是一种糖肽类抗生素,可以通过改变细胞膜的渗透性并选择性地抑制核糖核酸的合成以发挥抗菌活性。Vancomycin 可以用于治疗所有抗生素均无效的严重感染。 | |||
TN7028 |
Eurycomanol 2-O-β-D-glucopyranoside
|
Others | Others |
Eurycomanol 2-O-β-D-glucopyranoside是一种天然化合物,属于二萜类,提取于东革阿里。 | |||
TN3575 |
(±)-Cannabichromene
Cannabichromene,大麻色原烯,Cannabichrome |
Cannabinoid Receptor | GPCR/G Protein |
(±)-Cannabichromene 是一种发现于大麻的 2,2-dimethyl-2H-chromene 衍生物。 | |||
T3859 |
Isomucronulatol
7,2'-Dihydroxy-3',4'-dimethoxyisoflavan,7,2'-二羟基-3',4'-二甲氧基异黄烷,异短尖剑豆酚 |
Others | Others |
Isomucronulatol (7,2'-Dihydroxy-3',4'-dimethoxyisoflavan) 是一种黄酮类化合物,分离自 A. membranaceus 根。它在体外对 LPS 刺激产生的 IL-12 p40 有抑制作用,具有潜在的抗炎作用。 | |||
T8109 |
d-Neomenthol
(1S,2S,5R)-2-Isopropyl-5-Methylcyclohexanol,(1S,2S,5R)-(+)-新薄荷醇,(+)-Neomenthol |
Others | Others |
d-Neomenthol ((+)-Neomenthol) 是一种天然产物。 | |||
T67731 |
Holomycin
N-Demethylthiolutin |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Holomycin (N-Demethylthiolutin) 是二硫代吡咯酮类的次级代谢产物。 HolomycinHolomycin 是一种抗生素次级代谢物,是天然产光杆菌galatheae S2753形成生物膜所必需的,也是一种广谱抗生素。holomycin 通过其烯-二硫基团促进S2753的生物膜形成。 Holomycin 具有抗肿瘤活性,可参与 RNA 合成。 | |||
TN7209 |
3-bromopyrrole-2,5-dione
ZINC13379821,3-溴-1H-吡咯-2,5-二酮,3-Bromo-1H-pyrrole-2,5-dione |
Others | Others |
3-bromopyrrole-2,5-dione (ZINC13379821) 是一种海洋来源的天然产物,存在于 Axinella brevistyla。 | |||
TN4220 |
Homobutein
3-O-Methylbutein,2',4,4'-Trihydroxy-3-methoxychalcone |
Antioxidant; NF-κB; HDAC; Parasite; Immunology/Inflammation related | Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology; NF-κB; oxidation-reduction |
Homobutein (3-O-Methylbutein) 是 HDAC 和 NF-κB 的双重抑制剂,IC50 分别为 190 和 38 μM。 Homobutein 是一种铁螯合剂,具有抗癌、抗炎、抗寄生虫和抗氧化活性。 | |||
TN7207 |
Ethyl6-bromo-1H-indole-3-carboxylate
Ethyl 6-Bromoindole-3-carboxylate,ethyl 6-bromo-3-indolecarboxylate,ZINC13379655,6-溴吲哚-3-甲酸乙酯 |
Others | Others |
Ethyl6-bromo-1H-indole-3-carboxylate (Ethyl 6-Bromoindole-3-carboxylate) 是一种海洋来源的天然产物,存在于 Nocardiopsis sp。 | |||
T2481 |
Ascomycin
FK520,Immunomycin,子囊霉素,FR-900520 |
Phosphatase; Others; Antibiotic; Parasite; Antifungal | Metabolism; Microbiology/Virology; Others |
Ascomycin (Immunomycin) 是 Tacrolimus 的乙基类似物,具有免疫抑制特性。它也是一种大环聚酮类抗生素,具有抗疟疾、抗真菌和抗痉挛等多种生物活性。它可防止移植排斥,并具有用于各种皮肤病研究的潜力。 | |||
T3607 |
Leucomycin
吉他霉素,Kitasamycin,Leucomycin V,Turimycin |
Antibacterial; Antibiotic | Microbiology/Virology |
Leucomycin (Turimycin) 是一种由 Streptomyces kitasatoensis 产生的大环内酯类抗生素。 | |||
T3904 |
Gomisin J
|
Calcium Channel; AMPK | Chromatin/Epigenetic; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling |
Gomisin J 是在五味子中发现的小分子量木脂素,具有血管舒张活性,在非酒精性脂肪性肝病方面有研究潜力。 它通过激活 AMPK、LKB1 和 Ca2+/钙调蛋白依赖性蛋白激酶 II 以及抑制 HepG2 细胞中的胎球蛋白 A 来调节脂肪生成酶和脂肪分解酶以及炎症分子的表达,从而抑制脂质积累。 | |||
T11287 |
Filipin complex
|
Antifungal | Microbiology/Virology |
Filipin complex 是一种 28 元环戊烯大环内酯类抗真菌抗生素,由 S. filipinensis、S. avermitilis 和 S. miharaensis 产生的混合物,抑制 PRRSV 病毒进入细胞,通过与膜固醇相互作用发挥作用。 | |||
TN2268 |
Tetrahydromagnolol
|
Cannabinoid Receptor; GPR; GABA Receptor | Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
Tetrahydromagnolol 是 Magnolol 的主要代谢产物,是一种弱的GPR55受体拮抗剂。它是选择性大麻素CB2受体激动剂,EC50为 170 nM,Ki 为 416 nM,对CB2受体的选择性比 CB1 受体高 20 倍。 | |||
TN1511 |
Cleomiscosin A
|
LDL; Antioxidant; TNF | Apoptosis; Metabolism; oxidation-reduction |
Cleomiscosin A 来源于 Acer okamotoanum 的叶和树枝,对小鼠腹腔巨噬细胞的 TNF-α 分泌具有抑制活性。 Cleomiscosin A 可用于预防动脉粥样硬化病变中 LDL 氧化的研究。 | |||
T4757 |
L-Homoserine
(S)-2-氨基-4-羟基丁酸,(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID |
Others; Endogenous Metabolite | Metabolism; Others |
L-Homoserine ((S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID) 是天然存在的非蛋白丝氨酸,是合成苏氨酸、蛋氨酸和赖氨酸的共有中间体。它是氨基酸丝氨酸的更具反应性的变体。 | |||
T16338 |
Norgestimate metabolite Norelgestromin
17-Deacetyl norgestimate,17-Deacylnorgestimate,甲基孕酮 |
Drug Metabolite | Metabolism |
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) 是norgestimate 的一种活性代谢物。它是用于避孕贴片的甾体孕激素,与雌激素乙炔雌二醇结合使用。 | |||
TQ0312 |
Sphingomyelin
|
Endogenous Metabolite | Metabolism |
Sphingomyelin is a natural sphingolipid that existed in animal cell membranes. It implicates the regulation of transmembrane signaling. | |||
T5257 |
L-Homocitrulline
高瓜氨酸,Homo-L-citrulline,Homocitrulline |
Others; Endogenous Metabolite | Metabolism; Others |
L-Homocitrulline (Homocitrulline) 是一种代谢物,可在尿素循环障碍患者的尿液中大量检测到。在某些情况下,由于尿素循环的鸟氨酸供应耗尽而导致的氨甲酰磷酸酯的积累可能是 L-Homocitrulline 和高精氨酸合成增强的原因。 | |||
T14008 |
2,2,5,7,8-Pentamethyl-6-Chromanol
PMC |
Androgen Receptor | Endocrinology/Hormones |
2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) 是维生素 E (α-tocopherol) 的抗氧化部分,能够有效的调节雄激素受体 (androgen receptor) 信号,及抗前列腺癌细胞系的抗癌活性。 | |||
T6830 |
Epoxomicin
BU-4061T,BU-4061T,Aids010837,环氧酶素 |
Apoptosis; Proteasome | Apoptosis; Proteases/Proteasome; Ubiquitination |
Epoxomicin (BU-4061T,Aids010837) 是一种含环氧酮的天然产物,可穿越血脑屏障,并具有很强的抗肿瘤和抗炎活性。它是一种选择性不可逆的蛋白酶体抑制剂,抑制类胰凝乳蛋白酶的活性。 | |||
TN1742 |
Homovanillyl alcohol
高香草醇,4-羟基-3-甲氧基苯乙醇 |
TNF; Drug Metabolite | Apoptosis; Metabolism |
Homovanillyl alcohol 是羟基酪醇的生物代谢物。Hydroxytyrosol 是存在于原始橄榄油和葡萄酒中的酚类化合物。它能够保护红细胞免受氧化损伤,并对心血管具有保护作用。 | |||
T1419 |
Azithromycin hydrate
CP-62993 dihydrate,阿奇霉素二水物,Azithromycin dihydrate,阿奇霉素二水合物 |
ribosome; Antibacterial; Antibiotic; Autophagy | Autophagy; Microbiology/Virology |
Azithromycin hydrate (CP-62993 dihydrate) 是一种大环内酯抗生素,可研究细菌感染。 | |||
TN7165 |
3,6-Dibromocarbazole
3,6-Dibromo-9H-carbazole,3,6二溴咔唑 |
Others | Others |
3,6-Dibromocarbazole (3,6-Dibromo-9H-carbazole) 是一种海洋来源的天然产物,存在于Kyrtuthrix maculans。 | |||
T36818 |
Questiomycin A
|
GPR; Antibacterial | Endocrinology/Hormones; GPCR/G Protein; Microbiology/Virology |
Questiomycin A 是一种在鲜奶油中生产的抗生素,具有抗菌和抗癌活性。 Questiomycin A 抑制细胞保护性 ER 伴侣蛋白 GRP78 的表达。 | |||
TN7202 |
3-Chloro-6-Bromo Indole
6-溴-3-氯-1H-吲哚,6-bromo-3-chloro-1H-indole,3-CHLORO-6-BROMOINDOLE |
Others | Others |
3-Chloro-6-Bromo Indole (3-CHLORO-6-BROMOINDOLE) 是一种海洋来源的天然产物,存在于 Ptychodera flava。 | |||
TN7188 |
2-broMobenzene-1,3,5-triol
2-bromo-phloroglucinol,1,3,5-三羟基2-溴苯,Bromophloroglucinol,2-Bromo-1,3,5-benzenetriol |
Others | Others |
2-broMobenzene-1,3,5-triol (Bromophloroglucinol) 是一种海洋来源的天然产物,发现于 Rhabdonia verticillata。 | |||
T3672 |
Nomilin
|
MAPK | MAPK |
Nomilin 是一种柠檬苦素类化合物,从柑桔类提取物中获得,是抗肥胖症和降糖药。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00821 |
OM Protein, Human, Recombinant (His)
Oncomodulin-1,OCM,OM,OCMN,Parvalbumin Beta... |
Human | E. coli |
Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to... | |||
TMPH-03344 |
OM Protein, Rat, Recombinant (His)
|
Rat | P. pastoris (Yeast) |
Has some calmodulin-like activity with respect to enzyme activation and growth regulation. Binds two calcium ions. OM Protein, Rat, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 14.5 kDa and the accession number is P02631. | |||
TMPH-02816 |
OM Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
Has some calmodulin-like activity with respect to enzyme activation and growth regulation. Binds two calcium ions. | |||
TMPH-03343 |
OM Protein, Rat, Recombinant (E. coli, His)
|
Rat | E. coli |
Has some calmodulin-like activity with respect to enzyme activation and growth regulation. Binds two calcium ions. OM Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.0 kDa and the accession number is P02631. | |||
TMPY-03104 |
FGF-17 Protein, Human, Recombinant
fibroblast growth factor 17,HH20,FGF-13,FGF-17 |
Human | E. coli |
FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-13 is preferentially expressed in the embryonic brain. It interacts with FGFR3 and FGFR4. FGF-13 plays an important role in the regulation of embryonic development and as signaling mol... | |||
TMPY-03958 |
TGF alpha Protein, Human, Recombinant
transforming growth factor α,转化生长因子,transforming growth fact... |
Human | E. coli |
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (... | |||
TMPY-02521 |
HIST3H2A Protein, Human, Recombinant
histone cluster 3, H2a,MGC3165 |
Human | E. coli |
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enzymatic machinery that set them are crucial regulators that can control cellular proliferation, differentiation,... | |||
TMPY-02869 |
MMP-12 Protein, Human, Recombinant (catalytic domain)
HME,ME,MMP-12,MME,matrix metallopeptidase 12 |
Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ... | |||
TMPY-00105 |
Recombinant Protein G
|
E. coli | |
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig... | |||
TMPY-00005 |
FGF-8a Protein, Human, Recombinant
fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW... |
Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... | |||
TMPY-06983 |
IFN gamma Protein, Human, Recombinant (E. coli)
Interferon Gamma,IFN γ,IFN gamma,IFG,IFI,干扰素,Interferon γ |
Human | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-03195 |
Serum Amyloid P Protein, Human, Recombinant (His)
amyloid P component, serum,HEL-S-92n,SAP,PTX2 |
Human | HEK293 Cells |
Serum Amyloid P Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P02743. | |||
TMPK-00305 |
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,tβR-I,TGF-... |
Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. | |||
TMPK-00785 |
ANXA2 Protein, Mouse, Recombinant (His)
LIP2PAP-IV,Annexin II,LPC2DP36,LPC2D,CAL1H,Annexin A2,ANX2L4... |
Mouse | E. coli |
ANXA2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 39.6 kDa and the accession number is P07356. | |||
TMPY-05176 |
AMH Protein, Human, Recombinant (His)
MIS,anti-Mullerian hormone,MIF |
Human | HEK293 Cells |
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi... | |||
TMPY-05102 |
CD122/IL2RB Protein, Rat, Recombinant (His)
interleukin 2 receptor, β,interleukin 2 receptor, beta |
Rat | HEK293 Cells |
CD122/IL2RB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P26896. | |||
TMPY-05054 |
Notch 4 Protein, Human, Recombinant (His)
INT3,notch 4 |
Human | Baculovirus Insect Cells |
NOTCH4 (Notch Receptor 4) is a Protein Coding gene. Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance. The NOTCH4 gene is located at 6p21.3 and is involved in the development and patterning of the central nervous systems. It regulates signaling pathways associated with neuronal maturation, a process involved in the development and patterning of the central nervous system. The NOTCH4 gene has also been identified as a possibl... | |||
TMPY-04778 |
Prolactin Protein, Human, Recombinant (His)
prolactin |
Human | Baculovirus Insect Cells |
Prolactin Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24.3 kDa and the accession number is P01236. | |||
TMPY-04845 |
IL-3 Protein, Mouse, Recombinant
Il-3,白介素,PSF,HCGF,BPA,白细胞介素,MCGF,Csfmu,interleukin 3 |
Mouse | HEK293 Cells |
IL-3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.7 kDa and the accession number is P01586. | |||
TMPY-00690 |
Carbonic Anhydrase 9 Protein, Human, Recombinant (His)
Carbonic Anhydrase IX,MN,CAIX |
Human | HEK293 Cells |
Carbonic Anhydrase 9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.5 kDa and the accession number is A0A0S2Z3D0. | |||
TMPJ-00042 |
TSLP Protein, Human, Recombinant
TSLP,Thymic stromal lymphopoietin |
Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral... | |||
TMPY-03425 |
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ... |
Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... | |||
TMPY-03357 |
FGFR2 Protein, Mouse, Recombinant (hFc)
KGFR,AU043015,KGFRTr,Bek,Fgfr7,svs,fibroblast growth factor ... |
Mouse | HEK293 Cells |
FGFR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number is AAA39377.1. | |||
TMPY-00570 |
Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
ALPI,PALP,PLAP,PLAP-1,alkaline phosphatase, placental,IAP,AL... |
Human | P. pastoris (Yeast) |
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. | |||
TMPY-04329 |
Vimentin Protein, Human, Recombinant (His)
CTRCT30,HEL113,vimentin |
Human | Baculovirus Insect Cells |
Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. ... | |||
TMPY-05584 |
CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated
CD25,p55,interleukin 2 receptor, alpha,TCGFR,IL-2RA,IDDM10,I... |
Human | HEK293 Cells |
CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25 kDa and the accession number is P01589. | |||
TMPY-04529 |
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)
epidermal growth factor receptor,PIG61,ERBB1,NISBD2,ERBB,HER... |
Human | Baculovirus Insect Cells |
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1. | |||
TMPY-03284 |
IL-T4 Protein, Human, Recombinant (His)
ILT-4,MIR-10,leukocyte immunoglobulin like receptor B2,LIR-2... |
Human | HEK293 Cells |
IL-T4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is AAH36827.1. | |||
TMPY-04493 |
BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)
tumor necrosis factor receptor superfamily member 17,BCMA,CD... |
Human | HEK293 Cells |
BCMA/TNFRSF17 Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 33.3 kDa and the accession number is Q02223-1. | |||
TMPK-00782 |
PLAU/uPA Protein, Mouse, Recombinant (His & Avi)
PLAU,UPA,BDPLT5,ATF,u-PA,QPD,Urokinase,URK |
Mouse | HEK293 Cells |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC. PLAU/uPA Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.00 kDa and the accession number is P06869. | |||
TMPY-06021 |
CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His)
CD28 molecule |
Human,Cynomolgus,Rhesus | HEK293 Cells |
CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.6 kDa and the accession number is Q0PDN3. | |||
TMPY-05157 |
TGFBR2 Protein, Human, Recombinant (His)
LDS2B,FAA3,TAAD2,MFS2,TGFR-2,TGFbeta-RII,transforming growth... |
Human | Baculovirus Insect Cells |
TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173. | |||
TMPJ-00735 |
PDGF-BB Protein, Human, Recombinant
PDGF-BB,血小板源生长因子,PDGFBB |
Human | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In a... | |||
TMPJ-00235 |
TPO Protein, Human, Recombinant (His)
Megakaryocyte growth and development factor,C-mpl ligand,Thr... |
Human | HEK293 Cells |
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physi... | |||
TMPY-02031 |
B7-H3 Protein, Human, Recombinant (His)
CD276 molecule,B7-H3,4Ig-B7-H3,B7RP-2,B7H3 |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-01991 |
CD32A Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Fc fragment of IgG receptor IIa |
Cynomolgus | HEK293 Cells |
CD32A Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 22.9 kDa and the accession number is Q8SPW4. | |||
TMPY-02789 |
IL-33 Protein, Canine, Recombinant
白介素,interleukin 33,白细胞介素 |
Canine | E. coli |
IL-33 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.8 kDa and the accession number is O97863. | |||
TMPY-03915 |
IL-5 Protein, Human, Recombinant
TRF,白介素,EDF,interleukin 5,IL-5,白细胞介素 |
Human | E. coli |
IL-5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.1 kDa and the accession number is P05113. | |||
TMPY-04815 |
C1 inhibitor Protein, Rat, Recombinant (His)
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
Rat | HEK293 Cells |
C1 inhibitor Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.7 kDa and the accession number is A6HMR4. | |||
TMPY-00699 |
CD155/PVR Protein, Human, Recombinant (hFc)
poliovirus receptor,NECL5,HVED,PVS,Necl-5,TAGE4,CD155 |
Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P15151-1. | |||
TMPY-00716 |
CD89 Protein, Human, Recombinant (His)
Fc fragment of IgA receptor,CD89,XXbac-BPG230H20.5,FCAR,FcαR... |
Human | HEK293 Cells |
CD89 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is P24071-1. | |||
TMPY-03802 |
IL-17F Protein, Human, Recombinant (aa 31-163)
ML1,ML-1,IL-17F,interleukin 17F,CANDF6 |
Human | E. coli |
IL-17F Protein, Human, Recombinant (aa 31-163) is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is AAH70124.1. | |||
TMPY-05558 |
Recombinant Protein L, PE conjugated
|
E. coli | |
Recombinant Protein L, PE conjugated is expressed in E. coli expression system. | |||
TMPY-05586 |
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMIGD2,IGPR-1,transmembrane and immunoglobulin doma... |
Human | HEK293 Cells |
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu... | |||
TMPY-05779 |
Ephrin A1/EFNA1 Protein, Human, Recombinant (hFc)
EPLG1,TNFAIP4,ECKLG,LERK-1,LERK1,EFL1,EFNA1,B61,ephrin-A1 |
Human | HEK293 Cells |
Ephrin A1/EFNA1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.08 kDa and the accession number is P20827-1. | |||
TMPY-00863 |
IL-6 Protein, Human, Recombinant
BSF2,白细胞介素,HSF,IL-6,IFNB2,interleukin 6,HGF,Interleukin-6,白介... |
Human | E. coli |
IL-6 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 20.95 kDa and the accession number is P05231. | |||
TMPY-00949 |
VEGFR3/FLT4 Protein, Human, Recombinant (His)
VEGFR-3,PCL,FLT41,VEGF Receptor 3,VEGFR3,FLT-4,fms related t... |
Human | HEK293 Cells |
VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is P35916-1. | |||
TMPY-00841 |
IL-13RA2 Protein, Human, Recombinant (His)
CT19,interleukin 13 receptor, alpha 2,CD213A2,interleukin 13... |
Human | HEK293 Cells |
IL-13RA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q14627. | |||
TMPY-00167 |
HER2/ERBB2 Protein, Human, Recombinant
HER-2/neu,erb-b2 receptor tyrosine kinase 2,HER2,HERV7Q,HERV... |
Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 70 kDa and the accession number is P04626-1. | |||
TMPK-01074 |
CD163 Protein, Human, Recombinant (His & Avi)
CD163,HbSR,RM3/1,MM130,CD163 molecule,GHI/61,sCD163,SCARI1,M... |
Human | HEK293 Cells |
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation. CD163 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 111.4 kDa and th... | |||
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