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- 2000种与肝癌相关的化合物，可以用于抗肝癌药物研发和药理研究；
- 通路靶点包含PI3K/Akt/mTOR，EGFR, FGFR，Met等；
- 部分化合物已上市或进入临床期；
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
抗肝癌化合物库
Anti-Liver Cancer Compound Library
很棒在全球范围内，肝癌占癌症死亡率第三位。肝癌的主要病因包括乙肝、丙肝、酒精性脂肪性肝炎和非酒精性脂肪性肝炎（NASH）。许多细胞信号通路与肝癌的发生有关，如 PI3K/Akt/mTOR 信号通路，表皮生长因子受体(EGFR)、血管内皮生长因子受体(VEGFR)等 TargetMol 抗肝癌化合物库收集了 2000 种与肝癌相关的化合物，包括已经报道具有肝癌治疗作用的化合物，以及靶向肝癌相关靶点潜在治疗肝癌的化合物，是抗肝癌药物研发的良好工具。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
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抗肝癌化合物库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
SCI 文献
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化合物库组成
Apoptosis
Autophagy
NF-κB
PI3K
VEGFR
Reactive Oxygen Species
EGFR
Wnt/beta-catenin
mTOR
Akt
p38 MAPK
GSK-3
AMPK
ERK
Endogenous Metabolite
STAT
FGFR
JAK
Raf
CDK
Antibacterial
c-Met/HGFR
PDGFR
Ras
TGF-beta/Smad
Src
FLT
MEK
JNK
COX
MAPK
c-Kit
IκB/IKK
TNF
DNA-PK
DNA/RNA Synthesis
HER
ATM/ATR
S6 Kinase
Parasite
Dehydrogenase
HIV Protease
IL Receptor
Antibiotic
Ferroptosis
Caspase
RIP kinase
ALK
Bcr-Abl
Aurora Kinase
PDK
Mitophagy
Tyrosine Kinases
c-RET
Potassium Channel
NOD
Antifungal
Antioxidant
PKC
IGF-1R
PD-1/PD-L1
PPAR
PARP
Cytochromes P450
Kras
Calcium Channel
Influenza Virus
PI4K
Pim
Rho
IRAK
NO Synthase
ROS
Casein Kinase
Microtubule Associated
PKA
MMP
HDAC
Topoisomerase
Trk receptor
NOD-like Receptor (NLR)
HCV Protease
Mitochondrial Metabolism
Isocitrate Dehydrogenase (IDH)
Lipoxygenase
Nrf2
c-Fms
Virus Protease
Nucleoside Antimetabolite/Analog
Chk
Bcl-2 Family
5-HT Receptor
TAM Receptor
FAK
Interleukin
AChR
Syk
HIF/HIF Prolyl-Hydroxylase
Proteasome
HBV
ROCK
PDE
PTEN
Epigenetic Reader Domain
TLR
p53
NOS
Estrogen/progestogen Receptor
SIK
HSV
Antiviral
SARS-CoV
Beta Amyloid
Sodium Channel
Tyrosinase
Tie-2
Phosphatase
Adrenergic Receptor
E1/E2/E3 Enzyme
Antifection
Prostaglandin Receptor
GABA Receptor
Histone Methyltransferase
Adenosine Receptor
NADPH
Histamine Receptor
CSF-1R
Cholinesterase (ChE)
MNK
P-gp
HSP
Ephrin Receptor
ASK
MELK
Reverse Transcriptase
PLK
HIF
SGK
MLK
Carbonic Anhydrase
Transferase
Integrin
DYRK
RAAS
TOPK
Estrogen Receptor/ERR
Serine Protease
TRP/TRPV Channel
Aryl Hydrocarbon Receptor
DNA Alkylation
Cannabinoid Receptor
ATPase
Chloride channel
DNA Alkylator/Crosslinker
BACE
Glutathione Peroxidase
GTPase
c-Myc
Glucocorticoid Receptor
LDL
Gamma-secretase
Glucosidase
Opioid Receptor
CCR
CaMK
PGE Synthase
Porcupine
LRRK2
Sirtuin
transporter
KLF
Discoidin Domain Receptor (DDR)
Anti-infection
ROS Kinase
ADC Cytotoxin
BTK
Mdm2
Proton pump
RAR/RXR
DHFR
Dopamine Receptor
IFNAR
Histone Demethylase
Cholecystokinin Receptor
Hck
Serine/threonin kinase
Leukotriene Receptor
PYK2
RANKL/RANK
MAO
Drug Metabolite
DPP-4
Hedgehog/Smoothened
Somatostatin
cAMP
Lipid
Beta-Secretase
Free radical scavengers
Histone Acetyltransferase
Pyroptosis
RSV
GST
Retinoid Receptor
Aromatase
Phospholipase
NADPH-oxidase
HMG-CoA Reductase
S1P Receptor
Kinesin
Melanin-concentrating Hormone Receptor (MCHR)
Adenylyl Cyclase
NPC1L1
ROR
NEDD8
Arginase
YAP
LTR
Reductase
Na+/Ca2+ Exchanger
PERK
gp120/CD4
Progesterone Receptor
OCT
MRP
Antifolate
Serotonin Transporter
Cysteine Protease
Liver X Receptor
FXR
Glucokinase
IAP
Myosin
IRE1
UGT
Haspin Kinase
ABC Transporter
Monoamine Transporter
Fatty Acid Synthase
PAK
FAAH
ACK1
KSP
GluR
Thrombopoietin Receptor
DNA
DUB
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
SGLT
ATP Citrate Lyase
Wee1
BCRP
OXPHOS
Glutathione reductase
Acyltransferase
STING
Aminopeptidase
Decarboxylase
cGAS
hCE
PAI-1
Methionine Adenosyltransferase (MAT)
Hippo pathway
GPX
CRISPR/Cas9
Hydroxylase
Adenosine Deaminase
Complement System
DAPK
Gap Junction Protein
Platelet aggregation
DNA Methyltransferase
BMI-1
Sigma receptor
Thrombin
AhR
CFTR
PKM
Monoamine Oxidase
化合物库信息
| Empty | 99614-02-5 | 99-32-1 | 99-24-1 | 99105-77-8 | 99009-20-8 | 989-51-5 | 978-62-1 | 97-77-8 | 97682-44-5 | 97-53-0 | Empty |
| Ondansetron | Chelidonic acid | Methyl gallate | Sulcotrione | Pyrazoloacridine | (-)-Epigallocatechin Gallate | IMD-0354 | Disulfiram | Irinotecan | Eugenol | ||
| Empty | 973-67-1 | 96990-18-0 | 965-52-6 | 959841-49-7 | 95975-55-6 | 959551-10-1 | 958852-01-2 | 957-66-4 | 957054-30-7 | 956905-27-4 | Empty |
| 5,6,7-TRIMETHOXYFLAVONE | Momordin Ic | Nifuroxazide | (E)-Akt inhibitor-IV | Guggulsterone | NIH-12848 | GSK1059615 | Isolinderalactone | Pictilisib | PF-04217903 | ||
| Empty | 955977-50-1 | 955365-80-7 | 952021-60-2 | 951151-97-6 | 950736-05-7 | 95058-81-4 | 94805-82-0 | 946518-60-1 | 946128-88-7 | 945755-56-6 | Empty |
| PI-3065 | Adavosertib | PF 477736 | JNJ-38158471 | B-Raf IN 1 | Gemcitabine | Glycycoumarin | LY2409881 trihydrochloride | Ro 5126766 | XL019 | ||
| Empty | 945619-74-9 | 945614-12-0 | 945595-80-2 | 944842-54-0 | 944396-88-7 | 944396-07-0 | 943820-93-7 | 943540-75-8 | 943540-74-7 | 943319-70-8 | Empty |
| OPHIOPOGONIN D | Pexmetinib | AMG 900 | Decernotinib | NIBR-17 | Buparlisib | Wnt/β-catenin agonist 2 | JNJ-38877605 | JNJ-38877618 | Ponatinib | ||
| Empty | 943083-58-7 | 942918-07-2 | 942655-44-9 | 942507-42-8 | 942289-87-4 | 942183-80-4 | 941678-49-5 | 941575-71-9 | 940310-85-0 | 939805-30-8 | Empty |
| WIC1 | GSK-1070916 | JK-P3 | AZ304 | PI-828 | SCH772984 | Ruxolitinib | BIP-135 | NVP-BHG712 | EOC317 | ||
| Empty | 939681-36-4 | 938440-64-3 | 937807-66-4 | 937272-79-2 | 937270-47-8 | 937263-43-9 | 937174-76-0 | 936890-98-1 | 936446-61-6 | 936091-26-8 | Empty |
| G5-7 | KU-0063794 | Neurodazine | Pacritinib | (E/Z)-Zotiraciclib | Tucatinib | GSK-690693 | OSI-027 | NRC-2694 | Fedratinib | ||
| Empty | 936091-14-4 | 935888-69-0 | 935666-88-9 | 934826-68-3 | 934660-93-2 | 934526-89-3 | 934493-76-2 | 934389-88-5 | 934353-76-1 | 931695-79-3 | Empty |
| TG101209 | Oprozomib | AZD-1480 | Visomitin | Cobimetinib | Pilaralisib | Voxtalisib | LY-294002 hydrochloride | ENMD-2076 | ML-191 | ||
| Empty | 93-07-2 | 929007-72-7 | 92831-11-3 | 928037-13-2 | 927880-90-8 | 925705-73-3 | 925701-49-1 | 925069-34-7 | 923032-37-5 | 919936-70-2 | Empty |
| Veratric acid | DB07268 | MN-64 | Golvatinib | RAF265 | TG 100713 | KU60019 | PI-273 | Refametinib | GS87 |
Keywords
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