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Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 2

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Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 2
产品编号 TMAC-02511
别名 p-MDMX (Ser367), p-MDMX (S367), MDMX (p-Ser367), MDMX (p-S367)

Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MDMX (Ser367)。Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 可用于 WB,IHC。

Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 2

Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 2

Rating icon 还可以
Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 2
产品编号 TMAC-02511 别名 p-MDMX (Ser367), p-MDMX (S367), MDMX (p-Ser367), MDMX (p-S367)

Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MDMX (Ser367)。Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 可用于 WB,IHC。

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50 μL
¥ 1,490
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100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MDMX (Ser367) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MDMX (Ser367). Anti-Phospho-MDMX (Ser367) Polyclonal Antibody can be used in WB,IHC.
别名p-MDMX (Ser367), p-MDMX (S367), MDMX (p-Ser367), MDMX (p-S367)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from HeLa cells, treated with calyculinA (50ng/ml, 30mins), using MDM4 (Phospho-Ser367) antibody TMAC-02511. The lane on the right is treated with the synthesized peptide.
2. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using MDM4 (Phospho-Ser367) antibody TMAC-02511. The picture on the right is treated with the synthesized peptide.
应用
推荐剂量
WB: 1:500-3000; IHC: 1:50-100
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 367 (T-I-S(p)-A-P) derived from Human MDM4
抗原种属
human
Uniprot ID
化学信息
分子量Actual: 80 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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4个月前
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