- 全部删除
- 您的购物车当前为空
Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MDMX (Ser367)。Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 可用于 WB,IHC。
Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MDMX (Ser367)。Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-MDMX (Ser367) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MDMX (Ser367). Anti-Phospho-MDMX (Ser367) Polyclonal Antibody can be used in WB,IHC. |
别名 | p-MDMX (Ser367), p-MDMX (S367), MDMX (p-Ser367), MDMX (p-S367) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from HeLa cells, treated with calyculinA (50ng/ml, 30mins), using MDM4 (Phospho-Ser367) antibody TMAC-02511. The lane on the right is treated with the synthesized peptide. 2. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using MDM4 (Phospho-Ser367) antibody TMAC-02511. The picture on the right is treated with the synthesized peptide. |
应用 | |
推荐剂量 | WB: 1:500-3000; IHC: 1:50-100 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 367 (T-I-S(p)-A-P) derived from Human MDM4 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 80 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容