烟草单体化合物库

产品编号 L6820 Tobacco Monomer Library

库化合物信息 Excel SDF

人类种植和使用烟草已有数千年历史，其应用范围从用于宗教仪式和医疗实践，到现代社会中令人上瘾的烟草产品；尽管烟草通常与吸烟相关，但在草药学和医学中，烟草也展示出一些药用价值。在全球范围内，人们已经利用烟草植物的各个部分来治疗不同的疾病，如镇静作用：烟草在传统草药学中被用作镇静剂，可用于缓解焦虑和紧张情绪；抗生素效应：具有对抗细菌和真菌的作用。烟草中的一些单体成分如绿原酸（Chlorogenic acid）是一种活性膳食多酚，具有抗糖尿病、抗癌、抗肥胖、保护神经和抗高血压的特性；阿魏酸（Ferulic Acid）是烟草植物中的主要酚酸，被广泛应用于制药、食品和化妆品行业，具有抗炎和抗氧化作用，可改善多种病理生理状况。

TargetMol收集并构建了烟草单体化合物库，涵盖了烟草及烟雾中的各种天然产物，包括但不限于生物碱类、黄酮类、萜类等多种结构类型。这些天然产物的丰富性为研究提供了多样性的分子结构和功能，旨在为科学家提供一个有效的工具，可用于研究烟草中的单体成分在特定疾病模型中的作用机制，为疾病治疗提供新思路，寻找具有潜在治疗效果的新药物候选物，为新型药物研发提供有益的启示；探索烟草中的天然产物对人体健康的潜在影响，包括抗氧化、抗炎症等方面的生理效应。

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

规格
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

特别折扣等您来询!

如果上述化合物库无法满足您的需求，您可发送邮件至tech@targetmol.com咨询我们的技术专员，为您量身定制专属化合物库！

咨询化合物库

产品描述

750种烟草单体化合物的独特集合，可用于高通量筛选和高内涵筛选；
提供产品的分子结构、生物活性、靶点通路等生物学信息，为筛选提供理论方向和研究基础；
结构多样，含黄酮类、生物碱类、萜类在内的多种化合物类型，拥有详细的分类信息
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

TargetMol的化合物可以高度定制！ 了解更多

包装和存储

干粉或者DMSO溶液置于带二维码的储存管中，或排列于96孔板/384孔板；
蓝冰运输

文件下载

化合物库操作手册 (1.89 MB) TargetMol化合物库目录 (13.2 MB) 获取化合物库Excel和SDF列表文件

客户使用化合物库发表的文献

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..

10. Blood. 2021, 137(11): 1478-1490. 11. Nucleic Acids Research. 2021. 12. Nature Communications. 2023, 14(1): 7574. 13. Advanced Science. 2020, 7(16): 2000925. 14. Angewandte Chemie. 2021. 15. Acta Pharmaceutica Sinica B. 2022. 16. Protein & Cell. 2021, 12(11): 877-888. 17. Bone Research. 2023, 11(1): 54. 18. Pharmacology & Therapeutics. (2021): 107930. 19. Nature Communications. 2021, 12(1): 1-12. 20. Journal of Cell Biology. 2022, 221(5): e202112024.

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化合物库组成

Endogenous Metabolite (331)

Apoptosis (65)

Antibacterial (61)

Autophagy (36)

Antifungal (30)

Reactive Oxygen Species (28)

Antioxidant (27)

NF-κB (19)

COX (18)

Parasite (16)

Influenza Virus (15)

DNA/RNA Synthesis (12)

P450 (12)

Anti-infection (12)

Antibiotic (12)

TNF (11)

Tyrosinase (11)

PPAR (11)

AChR (10)

GABA Receptor (10)

Dehydrogenase (9)

Calcium Channel (9)

Ferroptosis (8)

TRP/TRPV Channel (8)

HIV Protease (7)

Nrf2 (7)

p38 MAPK (7)

5-HT Receptor (7)

IL Receptor (6)

Virus Protease (6)

Akt (6)

AMPK (6)

Mitophagy (6)

iGluR (5)

BCL (5)

PKC (5)

MMP (5)

Beta Amyloid (5)

PARP (5)

PI3K (5)

AChE (5)

HSV (4)

Interleukin (4)

ROS (4)

HBV (4)

Caspase (4)

NO Synthase (4)

ERK (4)

NADPH (4)

Mitochondrial Metabolism (3)

Sirtuin (3)

HIF/HIF Prolyl-Hydroxylase (3)

EGFR (3)

Cannabinoid Receptor (3)

Lipoxygenase (3)

HIF (3)

Antifection (3)

Monoamine Oxidase (3)

Adrenergic Receptor (3)

MAO (3)

JNK (3)

Adenosine Receptor (3)

PDE (3)

Wnt/beta-catenin (3)

Aminopeptidase (2)

P-gp (2)

HDAC (2)

ATP Citrate Lyase (2)

Transferase (2)

Prostaglandin Receptor (2)

FGFR (2)

DNA (2)

Estrogen/progestogen Receptor (2)

Phospholipase (2)

Phosphatase (2)

IκB/IKK (2)

GST (2)

Nucleoside Antimetabolite/Analog (2)

RAAS (2)

GluR (2)

Aryl Hydrocarbon Receptor (2)

Opioid Receptor (2)

Thrombin (2)

Imidazoline Receptor (2)

NMDAR (2)

Glucosidase (2)

NOS (2)

NOD-like Receptor (NLR) (1)

Arginase (1)

LTR (1)

CFTR (1)

Amino Acids and Derivatives (1)

p53 (1)

ATPase (1)

PDK (1)

Lipase (1)

AhR (1)

ROS Kinase (1)

MEK (1)

CYP19A1 (1)

S6 Kinase (1)

DHFR (1)

NPC1L1 (1)

Potassium Channel (1)

Proton pump (1)

Platelet aggregation (1)

Syk (1)

Transaminase (1)

NOD (1)

Microtubule Associated (1)

Carbonic Anhydrase (1)

HMG-CoA Reductase (1)

Sodium Channel (1)

MTH1 (1)

STAT (1)

Immunology/Inflammation related (1)

Norepinephrine (1)

Glucokinase (1)

Xanthine Oxidase (1)

VEGFR (1)

Chloride channel (1)

FAAH (1)

Topoisomerase (1)

Cysteine Protease (1)

Hexokinase (1)

PAFR (1)

DNA gyrase (1)

Drug Metabolite (1)

CDK (1)

Gamma-secretase (1)

Androgen Receptor (1)

Serine/threonin kinase (1)

Histamine Receptor (1)

Progesterone Receptor (1)

Factor Xa (1)

Free radical scavengers (1)

Fas/FasL (1)

Trk receptor (1)

SARS-CoV (1)

HSP (1)

Antiviral (1)

TGF-beta/Smad (1)

Acyltransferase (1)

PKA (1)

MAPK (1)

PGE Synthase (1)

Estrogen Receptor/ERR (1)

Serotonin Transporter (1)

Stearoyl-CoA Desaturase (SCD) (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty