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Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MKP-1 (Ser359)。Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody 可用于 IHC-P,IF(paraffin section),ELISA。
Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MKP-1 (Ser359)。Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody 可用于 IHC-P,IF(paraffin section),ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MKP-1 (Ser359). Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),ELISA. |
别名 | p-MKP-1 (Ser359), p-MKP-1 (S359), MK1 (p-Ser359), MK1 (p-S359) |
Ig Type | IgG |
交叉反应 | Human |
应用 | |
推荐剂量 | IHC-P: 1:100-300; ELISA: 1:10000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | dual specificity phosphatase 1(DUSP1) Homo sapiens The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferati |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human MKP1 around the phosphorylation site of Ser359. AA range:318-367 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 39 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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