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TargetMol | Compound Library

疼痛相关化合物库现货

Pain-Related Compound Library

产品编号 L2690

疼痛是一种与实际或潜在的组织损伤相关的不愉快的感觉和情绪情感体验,或与此相似的经历 ;作为六大生命体征之一,疼痛与呼吸、脉搏、血压、体温等同样重要,反映了身体的健康状态。疼痛按持续时间分为急性疼痛、慢性疼痛;按照病因分为伤害性疼痛和神经病理性疼痛;按感受系统分类表层疼痛、深层疼痛;还可根据来源分为内脏痛和体表痛。 疼痛的产生机制是一个复杂的过程,涉及多个层面,包括生理、心理和神经生物学方面,疼痛主要的机制包括:痛觉感受器的激活,痛觉感受器是分布在皮肤、内脏、骨骼肌和关节等部位的专门感知有害刺激的感觉神经末梢。致痛物质的释放:当组织损伤时,会释放多种致痛物质,如组胺、缓激肽、5-羟色胺、乙酰胆碱、前列腺素等,这些物质能激活痛觉感受器。此外还包括神经信号传导、中枢调控、心理因素等等 TargetMol收集了2780种疼痛相关活性化合物及靶向疼痛相关靶点的化合物,可用于疼痛相关研究。

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。

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产品编号 L2690

疼痛相关化合物库
规格
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 2780种疼痛相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
  • 结构多样,具有良好的细胞渗透性;
  • 详细的说明书,化合物结构、靶点信息、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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Library Customization | TargetMol 化合物库组成

5-HT Receptor
COX
Calcium Channel
Potassium Channel
Histamine Receptor
Sodium Channel
Autophagy
GABA Receptor
Apoptosis
AChR
TRP/TRPV Channel
Dopamine Receptor
p38 MAPK
ERK
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Opioid Receptor
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Raf
Adrenergic Receptor
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Antibacterial
JNK
MAPK
Ras
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MEK
iGluR
Parasite
Akt
TNF
S6 Kinase
P450
CDK
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Reactive Oxygen Species
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Lipoxygenase
Endothelin Receptor
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PPAR
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Casein Kinase
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Wnt/beta-catenin
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MRP
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transporter
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UGT
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ACK
HSP
STING
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GST
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NADPH-oxidase
DNA Methyltransferase
Protease-activated Receptor
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PD-1/PD-L1
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Apelin receptor
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GluCls
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RXFP receptor
DAPK
BMI-1
cholecystokinin
Microtubule Associated
HIF/HIF Prolyl-Hydroxylase
CFTR
Imidazoline Receptor
Kinesin
S1P Receptor

Keywords