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IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral) immunity before there is sufficient IgG. The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). Kappa (κ) chain, one of the two types of light chain in mammals, is encoded by the immunoglobulin kappa locus (IGK@) on chromosome 2. Only V and J segments are found in Ig light chains.
IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral) immunity before there is sufficient IgG. The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). Kappa (κ) chain, one of the two types of light chain in mammals, is encoded by the immunoglobulin kappa locus (IGK@) on chromosome 2. Only V and J segments are found in Ig light chains.
![IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]](https://cdn.targetmol.cn/group3/M00/02/B7/CgoaEWY7NkaEP17eAAAAAJQYpso835.png)
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 483 | 待询 | |
| 5 mg | ¥ 1,383 | 待询 | |
| 10 mg | ¥ 2,283 | 待询 | |
| 25 mg | ¥ 3,183 | 待询 |
| 产品描述 | IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral) immunity before there is sufficient IgG. The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). Kappa (κ) chain, one of the two types of light chain in mammals, is encoded by the immunoglobulin kappa locus (IGK@) on chromosome 2. Only V and J segments are found in Ig light chains. |
| 体外活性 | Increased levels of free Ig light chains have also been detected in various inflammatory diseases. Very recent studies have shown that Ig light chains not only activate mast cells but also dorsal root ganglia (Rijnierse, 2009)) and neutrophils (Braber and Thio (2012)), expanding their possible role as mediators in inflammatory disease. |
| 反应种属 | Human |
| 应用 | ELISA FACS Functional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 偶联 | Unconjugated |
| 分子量 | 809.9 |
| 分子式 | C37H59N7O13 |
| Smiles | C[C@@H](O)[C@H](N)C(NC(CC(O)=O)C(NC(CC1=CC=CC=C1)C(N[C@@H]([C@@H](O)C)C(NC(CC(C)C)C(N[C@H](C(N[C@H]([C@@H](C)CC)C(O)=O)=O)[C@@H](O)C)=O)=O)=O)=O)=O |
| 密度 | no data available |
| 存储 | |
| 溶解度信息 | DMSO: ≥81 mg/mL, Sonication is recommended. |
对于不同动物的给药剂量换算,您也可以参考 更多