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Anti-Phospho-MLKL (Ser358) Antibody (4T982) 是一种 Mouse 抗体,靶向 Phospho-MLKL (Ser358)。Anti-Phospho-MLKL (Ser358) Antibody (4T982) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
Anti-Phospho-MLKL (Ser358) Antibody (4T982) 是一种 Mouse 抗体,靶向 Phospho-MLKL (Ser358)。Anti-Phospho-MLKL (Ser358) Antibody (4T982) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,165 | 5日内发货 | |
100 μL | ¥ 1,975 | 5日内发货 | |
200 μL | ¥ 2,790 | 5日内发货 |
产品描述 | Anti-Phospho-MLKL (Ser358) Antibody (4T982) is a Mouse antibody targeting Phospho-MLKL (Ser358). Anti-Phospho-MLKL (Ser358) Antibody (4T982) can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
Ig Type | IgG |
克隆号 | 4T982 |
交叉反应 | (predicted:Human) |
应用 | |
推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
亚细胞定位 | Cytoplasm. Cell membrane. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction. |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Protein G purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015]. |
免疫原 | KLH conjugated Synthesised monomethylpeptide: human MLKL around the phosphorylation site of Ser358 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Necroptosis,SARS Coronavirus,Other Kinases |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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