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Anti-Phospho-MLKL (Ser358) Antibody (4T982)

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Anti-Phospho-MLKL (Ser358) Antibody (4T982)
产品编号 TMAB-01455

Anti-Phospho-MLKL (Ser358) Antibody (4T982) 是一种 Mouse 抗体,靶向 Phospho-MLKL (Ser358)。Anti-Phospho-MLKL (Ser358) Antibody (4T982) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-Phospho-MLKL (Ser358) Antibody (4T982)

Anti-Phospho-MLKL (Ser358) Antibody (4T982)

Rating icon 还可以
Anti-Phospho-MLKL (Ser358) Antibody (4T982)
产品编号 TMAB-01455

Anti-Phospho-MLKL (Ser358) Antibody (4T982) 是一种 Mouse 抗体,靶向 Phospho-MLKL (Ser358)。Anti-Phospho-MLKL (Ser358) Antibody (4T982) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MLKL (Ser358) Antibody (4T982) is a Mouse antibody targeting Phospho-MLKL (Ser358). Anti-Phospho-MLKL (Ser358) Antibody (4T982) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
4T982
交叉反应
(predicted:Human)
应用
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm. Cell membrane. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015].
抗原信息
免疫原
KLH conjugated Synthesised monomethylpeptide: human MLKL around the phosphorylation site of Ser358
抗原种属
Human
基因ID
Uniprot ID
研究领域
Necroptosis,SARS Coronavirus,Other Kinases
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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