Aminoethyl-SS-ethylalcohol (Compound 3) is an Alkyl-Chain-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Aminoethyl-SS-propionic acid is an ADC linker compound employed in ADC synthesis [1]. It functions as a cleavable linker in the conjugation of antibodies with drugs, allowing for targeted drug delivery.
Azido-PEG3-SS-PEG3-azide is a polyethylene glycol (PEG) based linker commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
Azidoethyl-SS-PEG2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable linker for antibody-drug conjugates (ADCs)[1]. It is employed in the synthesis of ADCs, facilitating the covalent attachment of drugs to antibodies through the formation of stable amide bonds.
Hydroxy-PEG3-SS-PEG3-alcohol is a 6 unit polyethylene glycol (PEG) linker that can be cleaved. It is commonly employed in the synthesis of antibody-drug conjugates (ADCs) [1].
Mal-NH-ethyl-SS-propionic acid, a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1], plays a crucial role in the modulation of drug release from the conjugate.
Propargyl-PEG1-SS-PEG1-acid is a two-unit polyethylene glycol (PEG) linker that is cleavable and commonly employed in the synthesis of antibody-drug conjugates (ADCs) [1].
Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable linker consisting of a 1-unit polyethylene glycol (PEG) backbone, designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].
Propargyl-PEG1-SS-PEG1-propargyl refers to a cleavable di-functional polyethylene glycol (PEG) linker composed of two units. This specific linker is employed in the synthesis of antibody-drug conjugates (ADCs), where it plays a critical role in linking the antibody to the drug. [1]