Name: Ravagalimab
Brand: TargetMol
SKU: T77143
Price: 1980 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 1,980

现货

5 mg

¥ 5,860

现货

10 mg

¥ 7,890

现货

25 mg

¥ 11,700

现货

50 mg

¥ 15,800

现货

生物活性

产品描述	Ravagalimab (ABBV-323) is a CD40 antagonist monoclonal antibody with an EC50 of 3.7 nM. Ravagalimab is being investigated for the treatment of inflammatory diseases such as Crohn’s disease and Sjögren’s syndrome (SS). Research focuses on evaluating its pharmacological activity, efficacy, and safety in patients with primary Sjögren’s syndrome (pSS), highlighting its role in immune modulation.
靶点活性	CD40:3.7 nM (EC50)
体外活性	Ravagalimab (0-100 nM，2 天) 处理原代人 B 细胞，Ravagalimab抑制了 CD86的上调，EC50 为 0.6 nM。[2]
别名	拉瓦加利单抗, ABBV-323, ABBV323
反应种属	Human
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型	Human IgG1 kappa
推荐同型对照	Human IgG1 kappa, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

分子量	145.95 kDa
CAS No.	2050816-56-1

储存&溶解度

存储	Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Ravagalimab