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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TMPRSS2 Polyclonal Antibody

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货号 TMAB-13615

Anti-TMPRSS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TMPRSS2。Anti-TMPRSS2 Polyclonal Antibody 可用于 WB,ELISA。

Anti-TMPRSS2 Polyclonal Antibody

Anti-TMPRSS2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13615

Anti-TMPRSS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TMPRSS2。Anti-TMPRSS2 Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-TMPRSS2 Polyclonal Antibody is a Rabbit antibody targeting TMPRSS2. Anti-TMPRSS2 Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WBELISA
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane and Secreted. Activated by cleavage and secreted.
组织特异性Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors (1,2). The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease, which is mainly expressed in the mouse prostate and kidney, and is also expressed in the human small intestine, prostate, colon, stomach and salivary gland (3,4). TMPRSS2 contains several domains, including a serine protease domain of the S1 family, a scavenger receptor cysteine-rich domain of group A, an LDL receptor class A domain and a transmembrane domain (3). TMPRSS2 is expressed as a full length form and a cleaved protease domain (5) and its expression is increased by androgenic hormones. TMPRSS2 is also expressed in prostate carcinoma, suggesting that it may play a role in prostate carcinogenesis (6).
抗原信息
免疫原
Recombinant Protein: human TMPRSS2 protein
抗原种属
Human
基因名称
TMPRSS2
基因ID
7113
蛋白名称
Transmembrane protease serine 2
Uniprot ID
O15393
功能
Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland.
化学信息
分子量Theoretical: 54 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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