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p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer.

p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 483 | 待询 | |
| 5 mg | ¥ 1,383 | 待询 | |
| 10 mg | ¥ 2,283 | 待询 | |
| 25 mg | ¥ 3,183 | 待询 |
| 产品描述 | p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer. |
| 体外活性 | p53 has been described as 'the guardian of the genome' because of its role in conserving stability by preventing genome mutation. p53 has many mechanisms of anticancer function and plays a role in apoptosis, genomic stability, and inhibition of angiogenesis. In its anti-cancer role, p53 works through several mechanisms: It can activate DNA repair proteins when DNA has sustained damage. It can induce growth arrest by holding the cell cycle at the G1/S regulation point on DNA damage recognition. It can initiate apoptosis, the programmed cell death if DNA damage proves to be irreparable [1][2][3]. |
| 分子量 | 1066.3 |
| 分子式 | C41H67N11O14S4 |
| 密度 | no data available |
| Sequence | H-DL-Lys-DL-Tyr-DL-Met-DL-Cys-DL-Asn-DL-Ser-DL-Ser-DL-Cys-DL-Met-OH |
| 存储 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度信息 | DMSO: ≥53.3 mg/mL, Sonication is recommended. |
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