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Anti-Phospho-ASK1 (Thr845) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ASK1 (Thr845)。Anti-Phospho-ASK1 (Thr845) Polyclonal Antibody 可用于 WB。
Anti-Phospho-ASK1 (Thr845) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ASK1 (Thr845)。Anti-Phospho-ASK1 (Thr845) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-ASK1 (Thr845) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ASK1 (Thr845). Anti-Phospho-ASK1 (Thr845) Polyclonal Antibody can be used in WB. |
别名 | p-ASK1 (Thr845), p-ASK1 (T845), Mitogen-activated protein kinase kinase kinase 5, MEKK5, MEKK 5, MEK kinase 5, MAPKKK5, MAPK/ERK kinase kinase 5, MAP3K5, M3K5, ASK1 (p-Thr845), ASK1 (p-T845), ASK-1, ASK1, Apoptosis signal-regulating kinase 1 |
Ig Type | IgG |
交叉反应 | Human |
应用 | |
推荐剂量 | WB: 1:1000-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | mitogen-activated protein kinase kinase kinase 5(MAP3K5) Homo sapiens Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by Re |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human ASK1 around the phosphorylation site of Thr845 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 155 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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